Inhibition by MK-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Brain Dopamine and Reward

1989 • 1,899 citations

Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

1991 • 1,212 citations

The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones

1990 • 1,021 citations

Blockade of “reverse tolerance” to cocaine and amphetamine by MK-801

1989 • 484 citations

Drug reinforcement studied by the use of place conditioning in rat

1982 • 482 citations

Chemical and structural analysis of the relation between cortical inputs and tyrosine hydroxylase-containing terminals in rat neostriatum

1984 • 467 citations

The neuropharmacological basis of reward

1991 • 457 citations

Time‐dose relationships for locomotor activity effects of morphine after acute or repeated treatment

1972 • 439 citations

Climbing behavior induced by apomorphine in mice: a simple test for the study of dopamine receptors in striatum

1976 • 341 citations

Heroin reward is dependent on a dopaminergic substrate

1981 • 333 citations

Glutamatergic Control of Dopamine Release in the Rat Striatum: Evidence for Presynaptic N‐Methyl‐D‐Aspartate Receptors on Dopaminergic Nerve Terminals

1991 • 324 citations

In vivo presynaptic control of dopamine release in the cat caudate nucleus—II. Facilitatory or inhibitory influence ofl-glutamate

1986 • 290 citations

Reinforcing effects of brain microinjections of morphine revealed by conditioned place preference

1982 • 238 citations

Repeated administration of MK-801 produces sensitization to its own locomotor stimulant effects but blocks sensitization to amphetamine

1991 • 238 citations

Electrophysiological responses of neurones in the nucleus accumbens to hippocampal stimulation and the attenuation of the excitatory responses by the mesolimbic dopaminergic system

1984 • 235 citations

Place preference conditioning reveals the involvement of D1-dopamine receptors in the motivational properties of μ- and κ-opioid agonists

1987 • 189 citations

Effects of morphine on striatal dopamine metabolism: Possible mechanism of its opposite effect on locomotor activity in rats and mice

1974 • 188 citations

The effects of chlorpromazine on psychomotor stimulant self-administration in the Rhesus monkey

1972 • 186 citations

Place Conditioning: A Simple and Effective Method for Assessing the Motivational Properties of Drugs

1987 • 175 citations

Blockade of D-1 receptors by SCH 23390 antagonizes morphine- and amphetamine-induced place preference conditioning

1987 • 169 citations

Motivational effects of opioids: influence of D-1 versus D-2 receptor antagonists

1988 • 156 citations

Effects of narcotic analgesics upon the locomotor activity and brain catecholamine content of the mouse.

1971 • 149 citations

Factors affecting voluntary morphine intake in self-maintained addicted rats

1964 • 147 citations

L-name and MK-801 attenuate sensitization to the locomotor-stimulating effect of cocaine

1993 • 133 citations

Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine

1991 • 131 citations

Rapid and dissociated changes in sensitivities of different dopamine receptors in mouse brain

1975 • 123 citations

Effect of dopaminergic stimulation or blockade on morphine-withdrawal aggression

1973 • 120 citations

Dopaminergic substrates of cocaine-induced place conditioning

1986 • 116 citations

Excitatory Amino Acid Neurotransmitters in the Corticostriate Pathway: Studies Using Intracerebral Microdialysis In Vivo

1986 • 109 citations

Conditioned place preference with morphine: The effect of extinction training on the reinforcing CR

1984 • 108 citations

Paradoxical reinforcing properties of apomorphine: Effects of nucleus accumbens and area postrema lesions

1983 • 102 citations

Neural basis of psychomotor stimulant and opiate reward: Evidence suggesting the involvement of a common dopaminergic system

1986 • 102 citations

5-HT3 receptor antagonists block morphine- and nicotine-induced place-preference conditioning

1988 • 98 citations

Cyclo (leucylglcine) inhibits the development of morphine induced analgesic tolerance and dopamine receptor supersensitivity in rats

1980 • 84 citations

The Neuropharmacological Basis of Reward

1991 • 71 citations

Conditioned place preference: An evaluation of morphine's positive reinforcing properties

1984 • 70 citations

Depression of Morphine-seeking Behaviour by Dopamine Inhibition

1974 • 67 citations

Chemical Interactions in Methamphetamine Reinforcement

1968 • 66 citations

Measuring morphine's capacity to establish a place preference

1989 • 65 citations

Rotational behavior mediated by dopaminergic and nondopaminergic mechanisms after intranigral microinjection of specific mu, delta and kappa opioid agonists.

1988 • 57 citations

Morphine-induced potentiation of brain stimulation reward is enhanced by MK-801

1993 • 57 citations

The NMDA receptor antagonist MK-801 elicits conditioned place preference in rats

1993 • 55 citations

Antinarcotic Effects of Standardized Ginseng Extract G115 on Morphine

1990 • 52 citations

The dopamine D2 receptor agonists, quinpirole and bromocriptine produce conditioned place preferences

1988 • 51 citations

β-phenylethylamine-, D-amphetamine- and L-amphetamine-induced place preference conditioning in rats

1983 • 50 citations

Different effects of short- and long-term treatment with imipramine on the apomorphine- and food-induced place preference conditioning in rats

1988 • 48 citations

The noncompetitive NMDA antagonist MK-801 fails to block amphetamine-induced place conditioning in rats

1994 • 48 citations

Stimulation of Dopamine Release from Cultured Rat Mesencephalic Cells by Naturally Occurring Excitatory Amino Acids: Involvement of Both N‐Methyl‐D‐Aspartate (NMDA) and Non‐NMDA Receptor Subtypes

1990 • 39 citations

Dose-dependent conditioned place preference produced by etonitazene and morphine

1992 • 34 citations

Methylxanthines (Caffeine and Theophylline) Blocked Methamphetamine‐induced Conditioned Place Preference in Mice but Enhanced That Induced by Cocaine

1992 • 30 citations

The NMDA receptor antagonist MK-801 prevents imipramine-induced supersensitivity to quinpirole

1992 • 23 citations

Effects of ginseng total saponin on cocaine-induced hyperactivity and conditioned place preference in mice

1996 • 22 citations

A possible role of AA2 excitatory amino acid receptors in the expression of stimulant drug effects

1990 • 22 citations

Role of N-methyl-d-aspartate receptors in dopamine D1-, but not D2-, mediated changes in striatal and accumbens neurotensin systems

1992 • 17 citations