Rat Brain Norepinephrine Metabolism: Substantial Clearance Through 3,4‐Dihydroxyphenylethyleneglycol Formation

Statistical Principles in Experimental Design

1992 • 4,547 citations

Neuropsychopharmacology of monoamines and their regulatory enzymes.

1974 • 416 citations

Application of seady-state kinetics to studies of the transfer of 5-hydroxyindoleacetic acid from brain to plasma.

1967 • 308 citations

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN–II

1966 • 209 citations

Physiological control of brain norepinephrine synthesis by brain tyrosine concentration

1978 • 209 citations

The rate of formation of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate in brain as an estimate of the rate of formation of norepinephrine.

1973 • 136 citations

Effect of Probenecid on the Levels of Monoamine Metabolites in the Rat Brain

1967 • 102 citations

CORRELATION BETWEEN TYROSINE HYDROXYLASE ACTIVITY AND CATECHOLAMINE CONCENTRATION OR TURNOVER IN BRAIN REGIONS¹

1977 • 81 citations

MASS FRAGMENTOGRAPHIC DETERMINATION OF SOME ACIDIC AND ALCOHOLIC METABOLITES OF BIOGENIC AMINES IN THE RAT BRAIN

1975 • 77 citations

Regulation in the central norepinephrine neurotransmission induced in vivo by alpha adrenoceptor active drugs.

1976 • 75 citations

Rat Brain and Plasma Norepinephrine Glycol Metabolites Determined by Gas Chromatography‐Mass Fragmentography

1981 • 75 citations

Acidic and neutral metabolites of norepinephrine: their metabolism and transport from brain.

1972 • 74 citations

Selective metabolic pathways for noradrena-line in the peripheral and in the central nervous system.

1974 • 74 citations

ACCUMULATION AND DISAPPEARANCE OF NORADRENALINE AND ITS MAJOR METABOLITES SYNTHESIZED FROM INTRAVENTRICULARLY INJECTED [³H]DOPAMINE IN THE RAT BRAIN

1974 • 73 citations

Simultaneous determination of indole- and catecholamines in small brain regions in the rat using a weak cation exchange resin

1976 • 71 citations

GLYCOL SULPHATE ESTER FORMATION FROM [¹⁴C]NORADRENALINE IN BRAIN AND THE INFLUENCE OF A COMT INHIBITOR

1971 • 64 citations

Brain 3,4-dihydroxyphenylethyleneglycol levels are dependent on central noradrenergic neuron activity

1982 • 54 citations

Regional Distribution and Production Rate of 3‐Methoxy‐4‐Hydroxyphenylethyleneglycol Sulphate (MHPG‐SO₄) in Rat Brain

1981 • 51 citations

Calculation of the rate of catecholamine synthesis from the rate of conversion of tyrosine-14C to catecholamines. Effect of adrenal demedullation on synthesis rates.

1969 • 50 citations

Brain noradrenergic neuronal activity affects 3,4-dihydroxyphenylethyleneglycol (DHPG) levels

1981 • 49 citations

Central noradrenergic activity and the formation of glycol sulfate metabolites of brain norepinephrine

1976 • 40 citations

A METHOD FOR THE ASSAY OF CONJUGATED 3,4‐DIHYDROXYPHENYLGLYCOL, A MAJOR NORADRENALINE METABOLITE IN THE RAT BRAIN

1976 • 33 citations

Separation of conjugated glycol metabolites of [3H]norepinephrine in the rat brain

1974 • 18 citations

FREE 3‐METHOXY‐4‐HYDROXYPHENYLETHYLENEGLYCOL IN THE CENTRAL NERVOUS SYSTEM OF THE RAT: SEMI‐AUTOMATED FLUOROMETRIC ASSAY, TURNOVER AND EFFECTS OF DRUGS

1979 • 17 citations

A SENSITIVE FLUOROMETRIC METHOD FOR THE ESTIMATION OF 3,4‐DIHYDROXYPHENYLETHYLENE GLYCOL SULPHATE IN BRAIN TISSUE

1978 • 15 citations

3, 4 dihydroxyphenylethyleneglycol (DHPG) formation: The major route of rat brain norepinephrine metabolism

1981 • 14 citations

Effects of amphetamine, electrical stimulation and stress on endogenous MOPEG-SO4 levels in rat brain

1978 • 13 citations

Effect of probenecid on mouse brain tyrosine hydroxylase activity and catecholamines

1980 • 8 citations