Interferon-γ reduces tumor-induced Ia− macrophage-mediated suppression: role of prostaglandin E2, Ia, and tumor necrosis factor-α

Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses.

1987 • 490 citations

Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity.

1982 • 481 citations

Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activities.

1984 • 386 citations

Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.

1989 • 349 citations

Tumor necrosis factor stimulates interleukin-1 and prostaglandin E2 production in resting macrophages

1986 • 344 citations

A simple method for quantitative, semiquantitative, and qualitative assay of protein

1978 • 245 citations

Enhancement of antigen- and mitogen-induced human T lymphocyte proliferation by tumor necrosis factor-alpha.

1988 • 221 citations

Interferons as macrophage-activating factors. III. Preferential effects of interferon-gamma on the interleukin 1 secretory potential of fresh or aged human monocytes.

1985 • 217 citations

Serum-free in vitro bioassay for the detection of tumor necrosis factor

1986 • 195 citations

Interferon-gamma reduces macrophage-suppressive activity by inhibiting prostaglandin E2 release and inducing interleukin 1 production.

1984 • 166 citations

Interferon-gamma: A Review

1989 • 156 citations

Synergistic activation of human monocytes by granulocyte-macrophage colony-stimulating factor and IFN-gamma. Increased TNF-alpha but not IL-1 activity.

1988 • 139 citations

Immunomodulatory properties of recombinant murine and human tumor necrosis factor.

1988 • 128 citations

Tumor necrosis factor α in autoimmunity: pretty girl or old witch?

1992 • 128 citations

Production of colony-stimulating factor by tumor cells and the factor-mediated induction of suppressor cells.

1988 • 112 citations

Suppressor cell activity in tumor-bearing mice. I. Dualistic inhibition by suppressor T lymphocytes and macrophages.

1978 • 111 citations

Inhibition of Interferon-Gamma May Suppress Allograft Reactivity by T Lymphocytes in Vitro and in Vivo

1985 • 94 citations

Injection of mice with antibody to interferon enhances the growth of transplantable murine tumors.

1983 • 94 citations

Prostaglandin E2-Mediated Inactivation of Various Killer Lineage Cells by Tumor-Bearing Host Macrophages

1988 • 91 citations

Comparative effects of tumor necrosis factor-alpha and IL-1 beta on mitogen-induced T cell activation.

1988 • 81 citations

Tumor necrosis factor-alpha as a proliferative signal for an IL-2-dependent T cell line: strict species specificity of action.

1989 • 74 citations

Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons.

1985 • 73 citations

Prostaglandin E2 inhibits human T-cell proliferation after crosslinking of the CD3-Ti complex by directly affecting T cells at an early step of the activation process

1987 • 70 citations

Mononuclear phagocytes; physiology and pathology

1986 • 68 citations

Suppressor Cell Activity in Tumor-Bearing Mice

1978 • 68 citations

Interferon‐γ is not an antiviral, but a growth‐promoting factor for t lymphocytes

1988 • 63 citations

Characterization of immunosuppressive functions of murine peritoneal macrophages induced with various agents

1992 • 57 citations

Enhancing effect of IFN-gamma on helper T cell activity and IL 2 production.

1985 • 49 citations

Differential Tumor Necrosis Factor Production by Human Monocyte Subsets

1990 • 46 citations

Switching on the macrophage-mediated suppressor mechanism by tumor cells to evade host immune surveillance.

1980 • 44 citations

Tumor growth increases la− macrophage synthesis of tumor necrosis factor-α and prostaglandin E2: changes in macrophage suppressor activity

1993 • 37 citations

Shifts in macrophage (Mφ) surface phenotypes during tumor growth: Association of Mac-2+ and Mac-3+ Mφ with immunosuppressive activity

1987 • 35 citations

Effect of prostaglandin E2 on the γ-interferon induction of antigen-presenting ability in P388D1 cells and on IL-2 production by T-cell hybridomas

1985 • 35 citations

Characterization of Macrophage Subsets Regulating Murine Natural Killer Cell Activity

1990 • 31 citations

Changes in Macrophage Populations: Phenotypic Differences between Normal and Tumor-Bearing Host Macro phages

1989 • 30 citations

Prostaglandin E2 Production by Mac-2+ Macrophages: Tumor-Induced Population Shift

1987 • 27 citations

Variations in Macrophage Antigen Phenotype: A Correlation Between Ia Antigen Reduction and Immune Dysfunction During Tumor Growth

1986 • 27 citations

Regulation of macrophage suppression and cytotoxicity by interferon role of Ia-bearing macrophages.

1982 • 25 citations

Down-Regulation of Macrophage I-A Expression in Tumor-Bearing Mice

1990 • 24 citations

Tumor-induced alteration in macrophage accessory cell activity on autoreactive T cells

1989 • 23 citations

Tumor modulation of autoreactivity: Decreased macrophage and autoreactive T cell interactions

1990 • 20 citations

Human IFN-gamma up-regulates IL-2 receptors in mitogen-activated T lymphocytes.

1990 • 19 citations

Down-regulation of interleukin 1 production by macrophages of sarcoma-bearing mice.

1987 • 18 citations

Monoclonal antibodies against murine IFN-gamma abrogate in vivo tumor immunity against RSV-induced murine sarcomas.

1987 • 18 citations

In vitro immune blastogenesis during contact sensitivity in tumor-bearing mice

1978 • 17 citations

Down-regulation of cytotoxic T lymphocyte development by a minor stimulating locus-induced suppressor cascade that involves Lyt-1+ suppressor T cells, IA- macrophages, and their factors.

1988 • 14 citations

Tumor-Induced Variations in a High Molecular Weight Inhibitory Monokine

1989 • 8 citations

Deleted Work

1955 • 0 citations

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