Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats.

Methods of Enzymatic Analysis

1975 • 20,446 citations

The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM

1988 • 2,463 citations

The Effect of Insulin on the Disposal of Intravenous Glucose: Results from Indirect Calorimetry and Hepatic and Femoral Venous Catheterization

1981 • 1,728 citations

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus.

1985 • 1,147 citations

Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats.

1987 • 792 citations

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus.

1981 • 628 citations

Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release.

1983 • 466 citations

Insulin Resistance is a Prominent Feature of Insulin-dependent Diabetes

1982 • 365 citations

Correlation between muscle glycogen synthase activity and in vivo insulin action in man.

1984 • 340 citations

A microfluorometric method for the determination of free fatty acids in plasma

1983 • 336 citations

An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects.

1988 • 292 citations

Kinetics of glucose disposal in whole body and across the forearm in man.

1987 • 268 citations

Effect of insulin on the distribution and disposition of glucose in man.

1985 • 259 citations

Glucose Transport Is Rate Limiting for Skeletal Muscle Glucose Metabolism in Normal and STZ-Induced Diabetic Rats

1988 • 208 citations

Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism.

1987 • 189 citations

Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus.

1988 • 169 citations

A (3H)2-Deoxyglucose Method for Comparing Rates of Glucose Metabolism and Insulin Responses Among Rat Tissues In Vivo: Validation of the Model and the Absence of an Insulin Effect on Brain

1984 • 166 citations

In vivo insulin sensitivity in the rat determined by euglycemic clamp

1983 • 155 citations

Correction of chronic hyperglycemia with vanadate, but not with phlorizin, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic skeletal muscle.

1989 • 117 citations

Glucose Storage Is a Major Determinant of in Vivo “Insulin Resistance” in Subjects with Normal Glucose Tolerance

1986 • 113 citations

Rate-limiting steps for insulin-mediated glucose uptake into perfused rat hindlimb

1986 • 109 citations

Estimation of the Pentose Cycle Contribution to Glucose Metabolism in Tissue in Vivo^*

1967 • 104 citations

In vivo glucose metabolism in the awake rat: Tracer and insulin clamp studies

1987 • 102 citations

Effect of dietary protein on in vivo insulin action and liver glycogen repletion

1989 • 97 citations

Quantitative analysis of glycogen repletion by nuclear magnetic resonance spectroscopy in the conscious rat.

1987 • 91 citations

A Comparison of the Relative Effects of Obesity and Non-insulin-dependent Diabetes Mellitus on In Vivo Insulin-stimulated Glucose Utilization

1984 • 87 citations

No accumulation of glucose in human skeletal muscle during euglycemic hyperinsulinemia

1988 • 85 citations

Muscle Glycogen Synthesis and Disposition of Infused Glucose in Humans With Reduced Rates of Insulin-Mediated Carbohydrate Storage

1988 • 64 citations

Glucose transport is rate limiting for skeletal muscle glucose metabolism in normal and STZ-induced diabetic rats

1988 • 61 citations

Insulin increases the maximum velocity for glucose uptake without altering the Michaelis constant in man. Evidence that insulin increases glucose uptake merely by providing additional transport sites.

1982 • 56 citations

Normalization of Insulin Sensitivity With Lithium in Diabetic Rats

1989 • 55 citations

Pathway of glycogen synthesis from glucose in hepatocytes maintained in primary culture.

1985 • 53 citations

The role of ATP and glucose 6-phosphate in the regulation of glycogen synthetase D phosphatase

1972 • 41 citations

Comparison of Insulin-mediated and Glucose-mediated Glucose Disposal in Patients with Insulin-dependent Diabetes Mellitus and in Nondiabetic Subjects

1985 • 41 citations

Adipocyte glycogen synthase and pyruvate dehydrogenase in obese and type II diabetic subjects

1986 • 40 citations

Glucose and fructose 6-phosphate cycle in humans

1986 • 35 citations

Glucose-6-phosphate stimulation of human muscle glycogen synthase phosphatase

1988 • 30 citations

A comparison of the relative effects of obesity and non-insulin-dependent diabetes mellitus on in vivo insulin-stimulated glucose utilization

1984 • 29 citations

Glucose 6-phosphate effects on deoxyglucose, glucose and methylglucose transport in rat adipocytes. Evidence for intracellular regulation of sugar transport by glucose metabolites

1984 • 26 citations

Normalization of insulin sensitivity with lithium in diabetic rats

1989 • 19 citations

Comparison of insulin-mediated and glucose-mediated glucose disposal in patients with insulin-dependent diabetes mellitus and in nondiabetic subjects

1985 • 13 citations