Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats.

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

1979 • 7,240 citations

The Effect of Insulin on the Disposal of Intravenous Glucose: Results from Indirect Calorimetry and Hepatic and Femoral Venous Catheterization

1981 • 1,728 citations

Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus.

1985 • 1,147 citations

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus.

1981 • 628 citations

Regulation of Splanchnic and Peripheral Glucose Uptake by Insulin and Hyperglycemia in Man

1983 • 517 citations

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.

1984 • 481 citations

Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release.

1983 • 466 citations

The Effect of Insulin Treatment on Insulin Secretion and Insulin Action in Type II Diabetes Mellitus

1985 • 464 citations

Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes

1985 • 461 citations

Insulin Resistance is a Prominent Feature of Insulin-dependent Diabetes

1982 • 365 citations

Glucose Toxicity for Human Endothelial Cells in Culture: Delayed Replication, Disturbed Cell Cycle, and Accelerated Death

1985 • 299 citations

New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus

1983 • 266 citations

Insulin Treatment Reverses the Insulin Resistance of Type II Diabetes Mellitus

1982 • 219 citations

Insulin Sensitivity and Insulin Binding to Monocytes in Maturity-Onset Diabetes

1979 • 189 citations

The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus

1985 • 125 citations

The Glucose Uptake of Human Adipose Tissue in Obesity

1971 • 118 citations

Effect of Fasting and Streptozotocin Diabetes on Insulin Binding and Action in the Isolated Mouse Soleus Muscle

1979 • 109 citations

Development of insulin resistance in normal dogs following alloxan-induced insulin deficiency

1977 • 89 citations

A Comparison of the Relative Effects of Obesity and Non-insulin-dependent Diabetes Mellitus on In Vivo Insulin-stimulated Glucose Utilization

1984 • 87 citations

Reversal of insulin resistance in type I diabetes after treatment with continuous subcutaneous insulin infusion.

1983 • 83 citations

Correction of hyperglycemia with phloridzin restores the glucagon response to glucose in insulin-deficient dogs: implications for human diabetes.

1985 • 60 citations

Lack of in Vivo Insulin Resistance in Controlled Insulin-Dependent, Type I, Diabetic Patients*

1984 • 50 citations

Improved Insulin Sensitivity in Patients with Type I Diabetes Mellitus After CSII

1985 • 48 citations

Impaired Insulin Action in Rats with Non-insulin-dependent Diabetes

1984 • 47 citations

Improved In Vivo Insulin Effect During Continuous Subcutaneous Insulin Infusion in Patients with IDDM

1984 • 46 citations

Hepatic and peripheral insulin resistance following streptozotocin-induced insulin deficiency in the dog

1985 • 45 citations

Abnormalities of Insulin Responses After Ambient and Previous Exposure to Glucose in Streptozocin-diabetic and Dexamethasone-treated Rats: Role of Hyperglycemia and Increased B-Cell Demands

1986 • 44 citations

Insulin release, insulin sensitivity, and glucose intolerance.

1980 • 39 citations

Effects of Feeding States on Lipid Radioactivity in Liver, Muscle and Adipose Tissue after Injection of Labelled Glucose in the Rat

1970 • 38 citations

Effect of insulin on renal potassium metabolism

1987 • 33 citations

A comparison of the relative effects of obesity and non-insulin-dependent diabetes mellitus on in vivo insulin-stimulated glucose utilization

1984 • 29 citations

Unresponsiveness to Glucose in a Streptozocin Model of Diabetes: Inappropriate Insulin and Glucagon Responses to a Reduction of Glucose Concentration

1985 • 26 citations

Improved in vivo insulin effect during continuous subcutaneous insulin infusion in patients with IDDM

1984 • 26 citations

In vivo and in vitro resistance to maximal insulin-stimulated glucose disposal in insulin deficiency

1985 • 25 citations

Impaired insulin action in rats with non-insulin-dependent diabetes

1984 • 22 citations

Acute- and Late-Phase Insulin Secretion and Glucose Tolerance in Mild Alloxan Diabetes in Dogs

1976 • 17 citations

Department of Medicina, Faculdade de Medicina da Universidade de Sao Paulo, Brazil

1976 • 9 citations