The origin of Gaussian distributions of synaptic potentials

Quantal components of the end‐plate potential

1954 • 2,182 citations

Spontaneous subthreshold activity at motor nerve endings

1952 • 1,820 citations

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

1992 • 1,792 citations

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release.

1979 • 1,408 citations

Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells

1992 • 809 citations

A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle

1987 • 786 citations

Quantal components of unitary EPSCs at the mossy fibre synapse on CA3 pyramidal cells of rat hippocampus.

1993 • 729 citations

Release of secretory products during transient vesicle fusion

1993 • 582 citations

Quantal analysis of synaptic potentials in neurons of the central nervous system.

1990 • 578 citations

SOME FEATURES OF THE SUBMICROSCOPIC MORPHOLOGY OF SYNAPSES IN FROG AND EARTHWORM

1955 • 576 citations

Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: a patch‐clamp study.

1990 • 545 citations

Capacitance measurements reveal stepwise fusion events in degranulating mast cells

1984 • 506 citations

Quantitation of junctional and extrajunctional acetylcholine receptors by electron microscope autoradiography after (125)I-α-bungarotoxin binding at mouse neuromuscular junctions

1976 • 398 citations

The end‐plate potential in mammalian muscle

1956 • 383 citations

Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ

1992 • 373 citations

A study of spontaneous miniature potentials in spinal motoneurones

1963 • 327 citations

The number of transmitter molecules in a quantum: an estimate from iontophoretic application of acetylcholine at the neuromuscular synapse.

1975 • 325 citations

Biophysical Aspects of Neuro-muscular Transmission

1956 • 312 citations

Synaptic vesicles immunoisolated from rat cerebral cortex contain high levels of glutamate

1989 • 297 citations

Activation and desensitization of glutamate-activated channels mediating fast excitatory synaptic currents in the visual cortex

1992 • 268 citations

Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse

1993 • 264 citations

Exocytosis

1990 • 260 citations

Post‐synaptic potentiation: interaction between quanta of acetylcholine at the skeletal neuromuscular synapse.

1975 • 259 citations

Final steps in exocytosis observed in a cell with giant secretory granules.

1987 • 255 citations

Localization of active spots within the neuromuscular junction of the frog

1956 • 232 citations

Multimodal Distribution of Frog Miniature Endplate Potentials in Adult, Denervated, and Tadpole Leg Muscle

1974 • 210 citations

Short-Term and Long-Term Plasticity and Physiological Differentiation of Crustacean Motor Synapses

1986 • 192 citations

Synaptic transmission and its duplication by focally applied acetylcholine in parasympathetic neurons in the heart of the frog

1971 • 189 citations

Studies on sympathetic B and C neurons and patterns of preganglionic innervation

1965 • 182 citations

Intrinsic Quantal Variability Due to Stochastic Properties of Receptor-Transmitter Interactions

1992 • 181 citations

Temporal coincidence between synaptic vesicle fusion and quantal secretion of acetylcholine.

1985 • 163 citations

Studies in Neurophysiology

1979 • 152 citations

Spontaneous potentials at sympathetic nerve endings in smooth muscle

1962 • 138 citations

Neurotransmitter vesicles

1983 • 137 citations

Glutamate in rat brain cortex synaptic vesicles: influence of the vesicle isolation procedure

1986 • 128 citations

Quantal components of the synaptic potential in the ciliary ganglion of the chick

1964 • 127 citations

Intracellular recordings from ganglia of the thoracic sympathetic chain of the guinea‐pig

1969 • 125 citations

Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction.

1990 • 122 citations

The formation of synapses in regenerating mammalian striated muscle

1974 • 121 citations

Membrane structure at synaptic junctions in area CA1 of the rat hippocampus

1986 • 120 citations

The characteristics of synaptic currents and responses to acetylcholine of rat submandibular ganglion cells

1981 • 119 citations

Characteristics of transmitter release at regenerating frog neuromuscular junctions

1974 • 115 citations

The formation of synapses in reinnervated mammalian striated muscle

1973 • 113 citations

The exocytotic fusion pore modeled as a lipidic pore

1992 • 112 citations

Ultrastructural distribution of 125I-toxin F binding sites on chick ciliary neurons: synaptic localization of a toxin that blocks ganglionic nicotinic receptors

1987 • 110 citations

The formation of synapses in amphibian striated muscle during development.

1975 • 108 citations

Acetylcholine receptor site density affects the rising phase of miniature endplate currents.

1980 • 101 citations

Fidia Research Foundation neuroscience award lectures

1987 • 99 citations

Fine structural distribution of acetylcholine receptors at developing mouse neuromuscular junctions

1983 • 96 citations

Neurotransmitter release and synaptic vesicle recycling

1990 • 95 citations

Origin of adenosine released from rat vas deferens by nerve stimulation

1982 • 88 citations

Acetylcholine‐induced current fluctuations and fast excitatory post‐synaptic currents in rabbit sympathetic neurones.

1983 • 87 citations

Spontaneous synaptic activity in sympathetic ganglion cells of the frog

1963 • 86 citations

On the quantal release of the transmitter at a sympathetic synapse

1963 • 81 citations

The formation of synapses in reinnervated and cross‐reinnervated striated muscle during development

1974 • 80 citations

The structure and function of cholinergic synaptic vesicles

1984 • 79 citations

Histograms of the unitary evoked potential of the mouse diaphragm show multiple peaks

1982 • 71 citations

Events leading to the opening and closing of the exocytotic fusion pore have markedly different temperature dependencies. Kinetic analysis of single fusion events in patch-clamped mouse mast cells

1992 • 69 citations

Small noradrenergic storage vesicles isolated from rat vas deferens--biochemical and morphological characterization.

1980 • 68 citations

Relation between subsynaptic receptor blockade and response to quantal transmitter at the mouse neuromuscular junction.

1981 • 65 citations

Estimation of Parameters for a Model of Transmitter Release at Synapses

1976 • 61 citations

Post‐natal development of ganglia in the lower lumbar sympathetic chain of the rat.

1984 • 58 citations

Solubilization and Partial Purification of a Presynaptic Membrane Protein Ensuring Calcium‐Dependent Acetylcholine Release from Proteoliposomes

1986 • 55 citations

Is the quantum of transmitter release composed of subunits? A critical analysis in the mouse and frog

1981 • 55 citations

Some properties of excitatory junction currents recorded from submucosal arterioles of guinea‐pig ileum.

1984 • 49 citations

Small mode miniature end plate potentials are increased and evoked in fatigued preparations and in high Mg2+ saline

1978 • 49 citations

A statistical model indicates that miniature end-plate potentials and unitary evoked end-plate potentials are composed of subunits

1981 • 47 citations

Confocal microscopy reveals coordinated calcium fluctuations and oscillations in synaptic boutons.

1993 • 46 citations

Release of acetylcholine by Xenopus oocytes injected with mRNAs from cholinergic neurons.

1991 • 46 citations

Free and bound acetylcholine in frog muscle.

1982 • 44 citations

Subunit composition of the spontaneous miniature end‐plate currents at the mouse neuromuscular junction.

1988 • 44 citations

Spontaneous multiquantal release at synapses in guinea‐pig hypogastric ganglia: evidence that release can occur in bursts.

1978 • 42 citations

Acetylcholine receptor-like molecules are found in both synaptic and extrasynaptic clusters on the surface of neurons in the frog cardiac ganglion

1989 • 41 citations

Space and time characteristics of transmitter release at the nerve‐electroplaque junction of Torpedo.

1993 • 40 citations

Unitary, quantal and miniature gaba-activated synaptic chloride currents in cultured neurons from the rat superior colliculus

1992 • 40 citations

Confocal microscopy reveals coordinated calcium fluctuations and oscillations in synaptic boutons

1993 • 40 citations

Reversible effect of depolarization by K-propionate on sub-miniature endplate potential to bell-miniature endplate potential ratios, on miniature endplate potential frequencies and amplitudes, and on synaptic vesicle diameters and densities in frog neuromuscular junctions

1988 • 26 citations

Subunits in quantal transmission at the mouse neuromuscular junction: Tests of peak intervals in amplitude distributions

1986 • 26 citations

Quantal and subquantal GABAergic transmissions in cultured rat hippocampal neurons

1993 • 14 citations

Frequency modulation of transmitter release

1993 • 14 citations

Two classes of spontaneous GABA-mediated miniature synaptic currents in cultured rat hippocampal neurons

1992 • 14 citations

The mechanism of exocytosis during secretion in mast cells.

1989 • 14 citations

Effects of stimulation on the multiquantal spontaneous synaptic potentials in guinea pig hypogastric ganglia

1981 • 7 citations

Vesicular or Quantal and Subquantal Transmitter Release

1994 • 3 citations