Neurotransmitter release and synaptic vesicle recycling

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

Quantal components of the end‐plate potential

1954 • 2,182 citations

EVIDENCE FOR RECYCLING OF SYNAPTIC VESICLE MEMBRANE DURING TRANSMITTER RELEASE AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 2,122 citations

Spontaneous subthreshold activity at motor nerve endings

1952 • 1,820 citations

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1985 • 1,425 citations

Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter release.

1979 • 1,408 citations

Co‐operative action of calcium ions in transmitter release at the neuromuscular junction

1967 • 1,326 citations

The separation of synaptic vesicles from nerve-ending particles (‘synaptosomes’)

1964 • 1,213 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

1983 • 1,162 citations

The statistical nature of the acetylcholine potential and its molecular components

1972 • 960 citations

A 38,000-dalton membrane protein (p38) present in synaptic vesicles.

1985 • 856 citations

TURNOVER OF TRANSMITTER AND SYNAPTIC VESICLES AT THE FROG NEUROMUSCULAR JUNCTION

1973 • 835 citations

Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse

1981 • 704 citations

Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.

1986 • 671 citations

SYNAPSES IN THE CENTRAL NERVOUS SYSTEM

1956 • 612 citations

SOME FEATURES OF THE SUBMICROSCOPIC MORPHOLOGY OF SYNAPSES IN FROG AND EARTHWORM

1955 • 576 citations

Coexistence of peptides and classical neurotransmitters

1983 • 559 citations

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections.

1983 • 555 citations

Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes.

1983 • 535 citations

Functional changes in frog neuromuscular junctions studied with freeze-fracture

1974 • 516 citations

The cytoskeletal architecture of the presynaptic terminal and molecular structure of synapsin 1.

1989 • 500 citations

Transmitter leakage from motor nerve endings

1977 • 443 citations

Synapsin I bundles F-actin in a phosphorylation-dependent manner

1987 • 409 citations

The fine structure of the neuromuscular junction of the frog

1960 • 396 citations

Vesicle hypothesis of the release of quanta of acetylcholine.

1980 • 364 citations

Advances in Cytopharmacology

1973 • 345 citations

Protein phosphorylation in the nervous system

1984 • 329 citations

Biophysical Aspects of Neuro-muscular Transmission

1956 • 312 citations

Characterization of synapsin I binding to small synaptic vesicles.

1986 • 304 citations

DEPLETION OF VESICLES FROM FROG NEUROMUSCULAR JUNCTIONS BY PROLONGED TETANIC STIMULATION

1972 • 296 citations

Effect of lanthanum ions on function and structure of frog neuromuscular junctions

1971 • 259 citations

Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils.

1986 • 246 citations

Ca2+-dependent recycling of synaptic vesicles at the frog neuromuscular junction.

1980 • 231 citations

A MOLECULAR DESCRIPTION OF NERVE TERMINAL FUNCTION

1983 • 229 citations

Differential effect of alpha-latrotoxin on exocytosis from small synaptic vesicles and from large dense-core vesicles containing calcitonin gene-related peptide at the frog neuromuscular junction.

1988 • 221 citations

Activation of protein kinase C augments evoked transmitter release

1987 • 217 citations

New instruments which facilitate rapid freezing at 83 K and 6 K

1982 • 211 citations

Synapsin I in Nerve Terminals: Selective Association with Small Synaptic Vesicles

1984 • 205 citations

Antagonism of the paralysis produced by botulinum toxin in the rat

1977 • 202 citations

Vesicle recycling and transmitter release

1979 • 195 citations

Estimates of quantal content during 'chemical potentiation' of transmitter release

1979 • 193 citations

Protein phosphorylation in the nervous system.

1985 • 177 citations

Synapsin I: an actin-bundling protein under phosphorylation control.

1987 • 176 citations

Nicotine‐evoked disassembly of cortical actin filaments in adrenal chromaffin cells

1986 • 171 citations

Synapsin I: A synaptic vesicle-associated neuronal phosphoprotein

1986 • 168 citations

Temporal coincidence between synaptic vesicle fusion and quantal secretion of acetylcholine.

1985 • 163 citations

LES COMPARTIMENTS D'ACETYLCHOLINE DE L'ORGANE ELECTRIQUE DE LA TORPILLE ET LEURS MODIFICATIONS PAR LA STIMULATION

1972 • 156 citations

Freeze-fracture studies of frog neuromuscular junctions during intense release of neurotransmitter. I. Effects of black widow spider venom and Ca2+-free solutions on the structure of the active zone.

1979 • 155 citations

Freeze-fracture studies of frog neuromuscular junctions during intense release of neurotransmitter. II. Effects of electrical stimulation and high potassium.

1979 • 146 citations

Effects of stimulation of the chorda tympani in bursts on submaxillary responses in the cat

1982 • 137 citations

Synaptophysin (p38) at the frog neuromuscular junction: its incorporation into the axolemma and recycling after intense quantal secretion.

1988 • 134 citations

Actin in the nervous system

1985 • 129 citations

Redistribution of synaptophysin and synapsin I during alpha-latrotoxin-induced release of neurotransmitter at the neuromuscular junction.

1990 • 122 citations

Is an acetylcholine transport system responsible for nonquantal release of acetylcholine at the rodent myoneural junction?

1985 • 117 citations

The specific effect of potassium on transmitter release by motor nerve terminals and its inhibition by calcium

1973 • 102 citations

Specific localization of the alpha-latrotoxin receptor in the nerve terminal plasma membrane.

1984 • 96 citations

Acetylcholine compartments in mouse diaphragm. Comparison of the effects of black widow spider venom, electrical stimulation, and high concentrations of potassium.

1978 • 95 citations

Destabilization of actin filaments as a requirement for the secretion of catecholamines from permeabilized chromaffin cells

1986 • 94 citations

The effects of prolonged repetitive stimulation in hemicholinium on the frog neuromuscular junction.

1975 • 94 citations

The effect of α-latrotoxin on the neurosecretory PC12 cell line: Studies on toxin binding and stimulation of transmitter release

1983 • 84 citations

Exocytosis and membrane recycling

1981 • 83 citations

Studies on α‐Latrotoxin Receptors in Rat Brain Synaptosomes: Correlation Between Toxin Binding and Stimulation of Transmitter Release

1982 • 83 citations

Pattern of presynaptic nerve activity can determine the type of neurotransmitter regulating a postsynaptic event

1984 • 82 citations

Mechanism of action of α-latrotoxin: the presynaptic stimulatory toxin of the black widow spider venom

1986 • 80 citations

Effects of black widow spider venom and Ca2+ on quantal secretion at the frog neuromuscular junction.

1986 • 80 citations

αLatrotoxin of the black widow spider venom opens a small, non-closing cation channel

1986 • 75 citations

Miniature endplate potential frequency and amplitude determined by an extension of Campbell's theorem

1985 • 73 citations

Transfer of synaptic vesicle antigens to the presynaptic plasma membrane during exocytosis.

1981 • 72 citations

Measurement of quantal secretion induced by ouabain and its correlation with depletion of synaptic vesicles.

1985 • 68 citations

Use of black widow spider venom to study the release of neurotransmitters.

1979 • 67 citations

Localization of synapsin I at the frog neuromuscular junction

1988 • 66 citations

Purification of the putative alpha-latrotoxin receptor from bovine synaptosomal membranes in an active binding form.

1985 • 63 citations

The effect of potassium on exocytosis of transmitter at the frog neuromuscular junction.

1988 • 61 citations

Coated vesicles and pits during enhanced quantal release of acetylcholine at the neuromuscular junction

1987 • 58 citations

Calcium and neuronal function

1988 • 52 citations

Immunohistochemical localization of a synaptic-vesicle antigen in a cholinergic neuron under conditions of stimulation and rest

1982 • 45 citations

Fluctuation analysis of nonideal shot noise. Application to the neuromuscular junction.

1986 • 40 citations

The phorbol ester, 12-O-tetradecanoyl-phorbol-13-acetate, enhances the evoked quanta release of acetylcholine at the frog neuromuscular junction

1987 • 38 citations

Effect of alpha‐latrotoxin on the frog neuromuscular junction at low temperature.

1988 • 33 citations

The relationship of pinocytosis and synaptic vesicles at the frog neuromuscular junction

1984 • 27 citations

Putting together the neuronal cytoskeleton

1987 • 15 citations

Coated vesicle morphology and sub-populations at the neuromuscular junction

1984 • 6 citations

Resting Calcium Levels and Evoked Release at the Neuromuscular Junction

1986 • 3 citations