Intracellular copper transport in cultured hepatoma cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Absorption, transport, and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin.

1985 • 1,331 citations

Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

1985 • 1,042 citations

Transcriptional regulation of the mouse metallothionein-I gene by heavy metals.

1981 • 601 citations

Overexpression of Metallothionein Confers Resistance to Anticancer Drugs

1988 • 600 citations

The Role of Glutathione in Copper Metabolism and Toxicity

1989 • 568 citations

Chemistry and Biochemistry of Metallothionein

1987 • 536 citations

Distinct metal-binding configurations in metallothionein.

1985 • 313 citations

Molecular Biology of Metallothionein Gene Expression

1987 • 214 citations

Nutritional and Physiological Significance of Metallothionein

1987 • 204 citations

Involvement of Metallothionein in the Hepatic Metabolism of Copper

1987 • 161 citations

Ultraviolet radiation-induced metallothionein-I gene activation is associated with extensive DNA demethylation

1983 • 159 citations

Crab metallothionein. Primary structures of metallothioneins 1 and 2.

1982 • 131 citations

Toxicological Significance of Metallothionein

1987 • 118 citations

In Vivo and in Vitro binding of platinum to metallothionein

1984 • 107 citations

Nucleotide sequence and expression of a Drosophila metallothionein.

1985 • 100 citations

Metallothionein Induction as a Potent Means of Radiation Protection in Mice

1987 • 71 citations

Copper transfer between Neurospora copper metallothionein and type 3 copper apoproteins

1982 • 65 citations

Metal binding sites of rat liver Cu-thionein

1982 • 62 citations

Promotion of radioresistance by metallothionein induction prior to irradiation

1987 • 58 citations

Nature of copper compounds in liver supernate and bile of rats: studies with 67 Cu

1973 • 52 citations

Resistance to copper toxicity of cultured hepatoma cells. Characterization of resistant cell lines.

1986 • 43 citations

Urinary metallothionein and tissue metal levels of rats injected with cadium, mercury, lead, copper or zinc

1983 • 40 citations

Studies on the metabolism of rat liver copper-metallothionein

1985 • 40 citations

Yeast copper-thionein can reconstitute the Japanese-lacquer-tree (Rhus vernicifera) laccase from the Type 2-copper-depleted enzyme via a direct copper(I)-transfer mechanism

1983 • 36 citations

Reconstitution of stellacyanin as a case of direct Cu(I) transfer between yeast copper thionein and ‘blue’ copper apoprotein

1983 • 34 citations

Transport and intracellular distribution of copper in a human hepatoblastoma cell line, HepG2

1986 • 31 citations

Protective Function of Metallothionein against Certain Anticancer Agents

1987 • 19 citations

Zinc-induced resistance to alkylating agents: Lack of correlation between cell survival and metallothionein content

1982 • 15 citations