A Spin Trap, N-tert-Butyl-α-phenylnitrone Extends the Life Span of Mice

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples

1977 • 8,468 citations

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design

1976 • 2,290 citations

A new murine model of accelerated senescence

1981 • 855 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

Dietary Restriction in Mice Beginning at 1 Year of Age: Effect on Life-Span and Spontaneous Cancer Incidence

1982 • 757 citations

Oxidative DNA damage and senescence of human diploid fibroblast cells.

1995 • 697 citations

Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory

1988 • 243 citations

Protection against oxidative damage to CNS by α-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel series of nonlipid free radical scavengers

1991 • 183 citations

Free radicals and reperfusion-induced arrhythmias: protection by spin trap agent PBN in the rat heart.

1987 • 179 citations

Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-α-phenylnitrone (PBN)

1990 • 135 citations

Spin-trappers and vitamin E prolong endurance to muscle fatigue in mice

1990 • 118 citations

The Spin-Trap N-tert-α-Phenylbutylnitrone Prolongs the Life Span of the Senescence-Accelerated Mouse

1995 • 110 citations

Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task

1989 • 107 citations

Age‐Related Regional Changes in Hydroxyl Radical Stress and Antioxidants in Gerbil Brain

1993 • 93 citations

Evidence that nitric oxide modulates drinking behaviour

1992 • 84 citations

Alpha-Phenyl-Tert-Butyl-Nitrone (PBN) Attenuates Hydroxyl Radical Production During Ischemia-Reperfusion Injury of Rat Brain: An EPR Study

1993 • 74 citations

Nitric oxide formation during light-induced decomposition of phenyl N-tert-butylnitrone

1993 • 68 citations

Protective activity of the spin trap tert-bytyl-α-phenyl nitrone (PBN) in reperfused rat heart

1992 • 40 citations

The Effect of PhenylTert-Butyl Nitrone (Pbn) on Ccl₄-Induced Rat Liver Injury Detected by Proton Magnetic Resonance Imaging (Mri)in vivoand Electron Microscopy (Em)

1990 • 32 citations

Protective Effects of Spin-Trapping Agents on Adriamycin-Induced Cardiotoxicity in Isolated Rat Atria

1991 • 30 citations

In vivo or in vitro administration of the nitrone spin-trapping compound, n-tert-butyl-α-phenylnitrone, (PBN) reduces age-related deficits in striatal muscarinic receptor sensitivity

1995 • 28 citations

Multiple mechanisms for inhibition of low density lipoprotein oxidation by novel cyclic nitrone spin traps.

1994 • 27 citations

alpha-Lipoic acid protects against hemolysis of human erythrocytes induced by peroxyl radicals.

1994 • 20 citations

Age differences in the effects of water deprivation on activity, water loss and survival of rats

1970 • 7 citations