Alpha-Phenyl-Tert-Butyl-Nitrone (PBN) Attenuates Hydroxyl Radical Production During Ischemia-Reperfusion Injury of Rat Brain: An EPR Study

The American Journal of Physiology

1899 • 5,863 citations

Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts

1986 • 2,052 citations

Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex

1978 • 876 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

Oxidants and the central nervous system: some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?

1989 • 471 citations

Ascorbate free radical as a marker of oxidative stress: An EPR study

1993 • 360 citations

Ascorbic acid in the brain

1993 • 289 citations

Detection of free radicals during brain ischemia and reperfusion by spin trapping and microdialysis

1992 • 190 citations

Protection against oxidative damage to CNS by α-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel series of nonlipid free radical scavengers

1991 • 183 citations

Protection from cerebral ischemic injury in gerbils with the spin trap agent N-tert-butyl-α-phenylnitrone (PBN)

1990 • 135 citations

In vivo spin trapping of free radicals generated in brain, spleen, and liver during γ radiation of mice

1986 • 111 citations

Generation and recycling of radicals from phenolic antioxidants

1990 • 92 citations

Distribution of spin-trapping compounds in rat blood and brain: In vivo microdialysis determination

1993 • 80 citations

The Free Radical Trapping Agent N-Tert.-Butyl-α-Phenylnitrone (PBN) Attenuates Cerebral Ischaemic Injury in Gerbils

1991 • 76 citations

Protective effect of a new anti-oxidant on the rat brain exposed to ischemia-reperfusion injury: Inhibition of free radical formation and lipid peroxidation

1991 • 46 citations

Spin traps inhibit formation of hydrogen peroxide via the dismutation of superoxide: implications for spin trapping the hydroxyl free radical

1991 • 20 citations

A continuous in vivo model of ischemia/reperfusion induced free radical formation in the cerebral spinal fluid (CSF) of pigs using spin-trapping agents and electron paramagnetic resonance (EPR) techniques

1990 • 13 citations

Reactions of copper(II)-N-polycarboxylate complexes with hydrogen peroxide in the presence of biological reductants: ESR evidence for the formation of hydroxyl radical.

1992 • 4 citations