Regulatory roles of carbohydrate ligands for selectins in the homing of lymphocytes

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

2000 • 3,456 citations

A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes

1998 • 1,001 citations

The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells

1999 • 839 citations

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

1997 • 735 citations

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

1996 • 723 citations

Chemokines and the Tissue-Specific Migration of Lymphocytes

2002 • 692 citations

Lymphocyte Cc Chemokine Receptor 9 and Epithelial Thymus-Expressed Chemokine (Teck) Expression Distinguish the Small Intestinal Immune Compartment

2000 • 620 citations

Chemokines in Immunity

2001 • 431 citations

Gata-3 Induces T Helper Cell Type 2 (Th2) Cytokine Expression and Chromatin Remodeling in Committed Th1 Cells

2000 • 390 citations

Neutrophil-neutrophil interactions under hydrodynamic shear stress involve L-selectin and PSGL-1. A mechanism that amplifies initial leukocyte accumulation of P-selectin in vitro.

1996 • 353 citations

Targeted Gene Disruption Demonstrates That P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is Required for P-Selectin–Mediated but Not E-Selectin–Mediated Neutrophil Rolling and Migration

1999 • 327 citations

The α(1,3)fucosyltransferases FucT-IV and FucT-VII Exert Collaborative Control over Selectin-Dependent Leukocyte Recruitment and Lymphocyte Homing

2001 • 315 citations

Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor γδ+ gut intraepithelial lymphocytes

2001 • 291 citations

Structure of the O-Glycans in GlyCAM-1, an Endothelial-derived Ligand for L-selectin

1995 • 291 citations

Specialized Contributions by α(1,3)-Fucosyltransferase-IV and FucT-VII during Leukocyte Rolling in Dermal Microvessels

2000 • 261 citations

Sulfotransferases of Two Specificities Function in the Reconstitution of High Endothelial Cell Ligands for L-selectin

1999 • 260 citations

Identification of a Major Carbohydrate Capping Group of the L-selectin Ligand on High Endothelial Venules in Human Lymph Nodes as 6-Sulfo Sialyl Lewis X

1998 • 246 citations

P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

2002 • 241 citations

A Novel, High Endothelial Venule–Specific Sulfotransferase Expresses 6-Sulfo Sialyl Lewisx, an L-Selectin Ligand Displayed by CD34

1999 • 221 citations

Binding of Glycosulfopeptides to P-selectin Requires Stereospecific Contributions of Individual Tyrosine Sulfate and Sugar Residues

2000 • 204 citations

P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

2002 • 196 citations

6'-Sulfated Sialyl Lewis x Is a Major Capping Group of GlyCAM-1

1994 • 191 citations

The fucosyltransferase FucT-VII regulates E-selectin ligand synthesis in human T cells.

1996 • 178 citations

P-Selectin Glycoprotein Ligand 1 (Psgl-1) Is a Physiological Ligand for E-Selectin in Mediating T Helper 1 Lymphocyte Migration

2000 • 162 citations

Sulfation of L-Selectin Ligands by an HEV-Restricted Sulfotransferase Regulates Lymphocyte Homing to Lymph Nodes

2001 • 161 citations

A Novel P-Selectin Glycoprotein Ligand-1 Monoclonal Antibody Recognizes an Epitope Within the Tyrosine Sulfate Motif of Human PSGL-1 and Blocks Recognition of Both P- and L-Selectin

1998 • 160 citations

Molecular Cloning and Characterization of anN-Acetylglucosamine-6-O-sulfotransferase

1998 • 157 citations

Expression of the α(1,3)Fucosyltransferase Fuc-TVII in Lymphoid Aggregate High Endothelial Venules Correlates with Expression of L-Selectin Ligands

1996 • 146 citations

Activation of Human Leukocytes Reduces Surface P-Selectin Glycoprotein Ligand-1 (PSGL-1, CD162) and Adhesion to P-Selectin In Vitro

2000 • 126 citations

Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: evidence for selectin-dependent and independent mechanisms

2000 • 124 citations

L-selectin–mediated Leukocyte Adhesion In Vivo: Microvillous Distribution Determines Tethering Efficiency, But Not Rolling Velocity

1999 • 122 citations

L-selectin binds to P-selectin glycoprotein ligand-1 on leukocytes: interactions between the lectin, epidermal growth factor, and consensus repeat domains of the selectins determine ligand binding specificity.

1996 • 121 citations

Reconstitution of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of α1→3 fucosyltransferase VII and newly cloned GlcNAcβ:6-sulfotransferase cDNA

1999 • 120 citations

Fuc-Tvii Is Required for T Helper 1 and T Cytotoxic 1 Lymphocyte Selectin Ligand Expression and Recruitment in Inflammation, and Together with Fuc-Tiv Regulates Naive T Cell Trafficking to Lymph Nodes

2001 • 118 citations

Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer.

2000 • 102 citations

Sialobiology and other novel forms of glycosylation

1999 • 100 citations

Modification of P-selectin glycoprotein ligand-1 with a natural killer cell-restricted sulfated lactosamine creates an alternate ligand for L-selectin

2000 • 93 citations

Human N-Acetylglucosamine-6-O-Sulfotransferase Involved in the Biosynthesis of 6-Sulfo Sialyl Lewis X: Molecular Cloning, Chromosomal Mapping, and Expression in Various Organs and Tumor Cells

1998 • 90 citations

6′-Sulfo Sialyl Lex but Not 6-Sulfo Sialyl Lex Expressed on the Cell Surface Supports L-selectin-mediated Adhesion

1996 • 88 citations

Important contributions of P-selectin glycoprotein ligand-1-mediated secondary capture to human monocyte adhesion to P-selectin, E-selectin, and TNF-alpha-activated endothelium under flow in vitro.

1998 • 85 citations

A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cells

1993 • 82 citations

The First Total Synthesis of 6-Sulfo-de-N-acetylsialyl Lewisx Ganglioside: A Superior Ligand for Human L-Selectin

1999 • 75 citations

Important Contributions of P-Selectin Glycoprotein Ligand-1-Mediated Secondary Capture to Human Monocyte Adhesion to P-Selectin, E-Selectin, and TNF-α-Activated Endothelium Under Flow In Vitro

1998 • 71 citations

Fucosyltransferase VII-Deficient Mice with Defective E-, P-, and L-Selectin Ligands Show Impaired CD4+ and CD8+ T Cell Migration into the Skin, but Normal Extravasation into Visceral Organs

2002 • 69 citations

Regulation of selectin binding activity by cyclization of sialic acid moiety of carbohydrate ligands on human leukocytes

1999 • 68 citations

Specificities ofN-Acetylglucosamine-6-O-sulfotransferases in Relation to L-selectin Ligand Synthesis and Tumor-associated Enzyme Expression

2002 • 61 citations

Distinct Sulfation Requirements of Selectins Disclosed Using Cells That Support Rolling Mediated by All Three Selectins under Shear Flow

2002 • 51 citations

Human T-Cell Leukemia Virus-1 Encoded Tax Protein Transactivates α1→3 Fucosyltransferase Fuc-T VII, Which Synthesizes Sialyl Lewis X, a Selectin Ligand Expressed on Adult T-Cell Leukemia Cells

1997 • 44 citations

P- and E-Selectins Recognize Sialyl 6-Sulfo Lewis X, the Recently Identified L-Selectin Ligand

2000 • 40 citations

Importance of L-selectin–dependent leukocyte–leukocyte interactions in human whole blood

2000 • 35 citations

Transcriptional Regulation of Expression of Carbohydrate Ligands for Cell Adhesion Molecules in the Selectin Family

2001 • 31 citations

Cutting Edge: Internalization of Transduced E-Selectin by Cultured Human Endothelial Cells: Comparison of Dermal Microvascular and Umbilical Vein Cells and Identification of a Phosphoserine-Type Di-leucine Motif

2002 • 30 citations

Studies on Selectin Blockers. 4. Structure−Function Relationships of Sulfated Sialyl Lewis X Hexasaccharide Ceramides toward E-, P-, and L-Selectin Binding

1997 • 30 citations

Variant type of sialyl Lewis X antigen expressed on adult T cell leukemia cells is associated with skin involvement.

1994 • 29 citations

Impaired Mucosal Immunity in L-Selectin-Deficient Mice Orally Immunized with aSalmonellaVaccine Vector

2001 • 29 citations

Human α(1,3)-Fucosyltransferase IV (FUTIV) Gene Expression Is Regulated by Elk-1 in the U937 Cell Line

2000 • 27 citations

Species-specific expression of sialosyl-Lex on polymorphonuclear leukocytes (PMN), in relation to selectin-dependent PMN responses

1994 • 25 citations

Glycobiology of Sialyl 6-Sulfo Lewis x, a New Carbohydrate Ligand for Selectins.

1999 • 13 citations

The α1 → 3 Fucosylation at the Penultimate GlcNAc Catalyzed by Fucosyltransferase VII Is Blocked by Internally Fucosylated Residue in Sialosyl Long-Chain Poly-LacNAc: Enzymatic Basis for Expression of Physiological E-Selectin Epitope

1998 • 13 citations

Especially Polymorphonuclear Leukocytes, but also Monomorphonuclear Leukocytes, Roll Spontaneously in Venules of Intact Rat Skin: Involvement of E-Selectin

2002 • 12 citations

NMR analysis of novel ganglioside GM4 analogues containing de‐N‐acetyl and lactamized sialic acid: probes for searching new ligand structures for human L‐selectin

2002 • 5 citations