Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma.

Parental imprinting of the mouse insulin-like growth factor II gene

1991 • 1,773 citations

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

1990 • 1,650 citations

Relaxation of imprinted genes in human cancer

1993 • 792 citations

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1993 • 710 citations

Genomic imprinting: review and relevance to human diseases.

1990 • 621 citations

Rhabdomyosarcoma: A clinicopathological study and classification of 39 cases

1958 • 561 citations

Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism

1985 • 555 citations

Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma

1993 • 546 citations

Genomic imprinting determines methylation of parental alleles in transgenic mice

1987 • 480 citations

Parental legacy determines methylation and expression of an autosomal transgene: A molecular mechanism for parental imprinting

1987 • 478 citations

Uniparental paternal disomy in a genetic cancer-predisposing syndrome

1991 • 432 citations

Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome

1993 • 427 citations

Degree of methylation of transgenes is dependent on gamete of origin

1987 • 407 citations

Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma.

1993 • 373 citations

Embryological and molecular investigations of parental imprinting on mouse chromosome 7

1991 • 314 citations

Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping

1987 • 273 citations

A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting.

1989 • 260 citations

Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors.

1990 • 242 citations

Molecular differential pathology of rhabdomyosarcoma

1989 • 225 citations

Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation

1987 • 202 citations

Polymerase chain reaction (PCR) for detection of APal polymorphism at the insulin like growth factor II gene (IGF2)

1991 • 105 citations

Genomic imprinting and embryonal tumours

1989 • 88 citations