Probiotics and immunity: A fish perspective

Effect of aquaculture on world fish supplies

2000 • 2,931 citations

Probiotic Bacteria as Biological Control Agents in Aquaculture

2000 • 2,172 citations

Bacterial Adherence: Adhesin-Receptor Interactions Mediating the Attachment of Bacteria to Mucosal Surfaces

1981 • 1,486 citations

The role of probiotics in aquaculture

2006 • 1,252 citations

The use of probiotics in aquaculture

1999 • 1,192 citations

Innate host defense mechanisms of fish against viruses and bacteria

2001 • 1,143 citations

Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics

2004 • 1,052 citations

Probiotics: an overview of beneficial effects.

2002 • 964 citations

Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota

2004 • 912 citations

The use of bacterial spore formers as probiotics: Table 1

2004 • 912 citations

Lactobacilli Differentially Modulate Expression of Cytokines and Maturation Surface Markers in Murine Dendritic Cells

2002 • 895 citations

Probiotics in aquaculture: The need, principles and mechanisms of action and screening processes

2007 • 780 citations

Probiotic use in clinical practice: what are the risks?

2006 • 735 citations

Studies on Bacillus subtilis and Lactobacillus acidophilus, as potential probiotics, on the immune response and resistance of Tilapia nilotica (Oreochromis niloticus) to challenge infections

2008 • 643 citations

Control of luminous Vibrio species in penaeid aquaculture ponds

1998 • 628 citations

A humanized gnotobiotic mouse model of host–archaeal–bacterial mutualism

2006 • 624 citations

Immunity to bacteria in fish

1999 • 583 citations

Monostrain, multistrain and multispecies probiotics—A comparison of functionality and efficacy

2004 • 580 citations

Antimicrobial substance from a human Lactobacillus strain

1987 • 577 citations

Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation

2006 • 574 citations

Fish nutrition in practice

1993 • 551 citations

The Probiotic Bacterium Lactobacillus casei Induces Activation of the Gut Mucosal Immune System through Innate Immunity

2006 • 504 citations

The use and selection of probiotic bacteria for use in the culture of larval aquatic organisms

2000 • 492 citations

Use of probiotics to control furunculosis in rainbow trout, Oncorhynchus mykiss (Walbaum)

2002 • 485 citations

Effects of a probiotic bacterium on black tiger shrimp Penaeus monodon survival and growth

1998 • 477 citations

Probiotics in aquaculture: Challenges and outlook

2008 • 473 citations

Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures

2000 • 460 citations

Cytokines and innate immunity of fish

2001 • 459 citations

Probiotics. The other half of the antibiotics story

1974 • 432 citations

Immune enhancement in rainbow trout (Oncorhynchus mykiss) by potential probiotic bacteria (Lactobacillus rhamnosus)

2003 • 426 citations

Use of Carnobacterium sp. as a probiotic for Atlantic salmon (Salmo salar L.) and rainbow trout (Oncorhynchus mykiss, Walbaum)

2000 • 419 citations

A probiotic strain of Vibrio alginolyticus effective in reducing diseases caused by Aeromonas salmonicida, Vibrio anguillarum and Vibrio ordalii

1995 • 405 citations

Inhibition of Vibrio anguillarum by Pseudomonas fluorescens AH2, a Possible Probiotic Treatment of Fish

1999 • 403 citations

Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteria

1996 • 403 citations

Control of pathogenic Vibrio spp. by Bacillus subtilis BT23, a possible probiotic treatment for black tiger shrimp Penaeus monodon

2003 • 385 citations

The viability of probiotic bacteria as a factor influencing the immune response in rainbow trout Oncorhynchus mykiss

2004 • 376 citations

Innate immune responses in rainbow trout (Oncorhynchus mykiss, Walbaum) induced by probiotics

2006 • 350 citations

Techniques for microbial control in the intensive rearing of marine larvae

1999 • 344 citations

Interaction of lactic acid bacteria with the gut immune system

2002 • 335 citations

Immune responses in rainbow trout Oncorhynchus mykiss induced by a potential probiotic bacteria Lactobacillus rhamnosus JCM 1136

2004 • 334 citations

Prebiotics, probiotics and human gut microbiology

1999 • 332 citations

Lactic acid bacteria and their effect on the immune system.

2001 • 328 citations

Microbes versus microbes: immune signals generated by probiotic lactobacilli and their role in protection against microbial pathogens

2002 • 324 citations

Bacillus subtilis AB1 controls Aeromonas infection in rainbow trout (Oncorhynchus mykiss, Walbaum)

2007 • 319 citations

Dietary administration of the probiotic, Lactobacillus plantarum, enhanced the growth, innate immune responses, and disease resistance of the grouper Epinephelus coioides

2009 • 312 citations

Functional Genomic and Metabolic Studies of the Adaptations of a Prominent Adult Human Gut Symbiont, Bacteroides thetaiotaomicron, to the Suckling Period

2006 • 308 citations

Risks associated with the use of chemicals in pond aquaculture

1999 • 304 citations

Growth improvement by probiotic in European sea bass juveniles (Dicentrarchus labrax, L.), with particular attention to IGF-1, myostatin and cortisol gene expression

2006 • 303 citations

Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract

2002 • 297 citations

Immune modulation and expression of cytokine genes in rainbow trout Oncorhynchus mykiss upon probiotic feeding

2006 • 292 citations

Dietary probiotic supplementation enhances natural killer cell activity in the elderly: an investigation of age-related immunological changes.

2001 • 289 citations

Dietary administration of Lactobacillus delbrüeckii and Bacillus subtilis, single or combined, on gilthead seabream cellular innate immune responses

2005 • 282 citations

Oral administration of yeast, Saccharomyces cerevisiae, enhances the cellular innate immune response of gilthead seabream (Sparus aurata L.)

2002 • 281 citations

Microbial Ecology of the Gastrointestinal Tract of Fish and the Potential Application of Prebiotics and Probiotics in Finfish Aquaculture

2005 • 277 citations

Selection and Identification of Autochthonous Potential Probiotic Bacteria from Turbot Larvae (Scophthalmus maximus) Rearing Units

2004 • 277 citations

Protection of rainbow trout (Oncorhynchus mykiss) from furunculosis by Lactobacillus rhamnosus

2001 • 275 citations

The intestines of carnivorous fish: structure and functions and the relations with diet.

1997 • 260 citations

Effect of probiotics, Enteroccus faecium, on tilapia (Oreochromis niloticus) growth performance and immune response

2008 • 260 citations

Review of probiotics available to modify gastrointestinal flora

1999 • 252 citations

Probiotic Bacteria: Legislative Framework—Requirements to Evidence Basis1,

2007 • 246 citations

Induction by a Lactic Acid Bacterium of a Population of CD4⁺T Cells with Low Proliferative Capacity That Produce Transforming Growth Factor β and Interleukin-10

2001 • 244 citations

Role of viability of probiotic strains in their persistence in the gut and in mucosal immune stimulation

2004 • 244 citations

Monospecies and multispecies probiotic formulations produce different systemic and local immunostimulatory effects in the gilthead seabream (Sparus aurata L.)

2008 • 237 citations

Enhancement of the immune response and protection induced by probiotic lactic acid bacteria against furunculosis in rainbow trout (Oncorhynchus mykiss)

2007 • 235 citations

Lactic acid bacteria increase the resistance of turbot larvae,Scophthalmus maximus,against pathogenic vibrio

1994 • 234 citations

Differential immunomodulatory properties of Bifidobacterium logum strains: relevance to probiotic selection and clinical applications

2007 • 233 citations

Effect of treatment with probiotics as water additives on tilapia (Oreochromis niloticus) growth performance and immune response

2009 • 230 citations

Enhanced innate immune parameters in Labeo rohita (Ham.) following oral administration of Bacillus subtilis

2007 • 228 citations

Identification of strong interleukin‐10 inducing lactic acid bacteria which down‐regulate T helper type 2 cytokines

2005 • 225 citations

Modulation of Nonspecific Mechanisms of Defense by Lactic Acid Bacteria: Effective Dose

1999 • 220 citations

Use of a probiotic to control lactococcosis and streptococcosis in rainbow trout, Oncorhynchus mykiss (Walbaum)

2005 • 220 citations

Competition for attachment of aquaculture candidate probiotic and pathogenic bacteria on fish intestinal mucus

2004 • 218 citations

Changes in intestinal microbiota and humoral immune response following probiotic administration in brown trout (Salmo trutta)

2007 • 217 citations

Effect of dietary supplementation of probiotic and vitamin C on the immune response of Indian major carp, Labeo rohita (Ham.)

2007 • 216 citations

Probiotic effect of lactic acid bacteria in the feed on growth and survival of fry of Atlantic cod (Gadus morhua)

1997 • 214 citations

Use of live and dead probiotic cells in tilapia Oreochromis niloticus

2006 • 213 citations

Divergent Patterns of Colonization and Immune Response Elicited from Two IntestinalLactobacillusStrains That Display Similar Properties In Vitro

2002 • 213 citations

Probiotics in aquaculture: importance and future perspectives

2008 • 210 citations

Early treatment with Lactobacillus delbrueckii strain induces an increase in intestinal T-cells and granulocytes and modulates immune-related genes of larval Dicentrarchus labrax (L.)

2009 • 205 citations

Protective effects and mechanisms of a probiotic bacterium Lactobacillus rhamnosus against experimental Edwardsiella tarda infection in tilapia (Oreochromis niloticus)

2006 • 203 citations

Effects of the probiotic,Lactobacillus acidophilus, on the growth performance, haematology parameters and immunoglobulin concentration in African Catfish (Clarias gariepinus, Burchell 1822) fingerling

2009 • 200 citations

Effects of supplementing the feed to Atlantic cod (Gadus morhua) fry with lactic acid bacteria and immuno-stimulating peptides during a challenge trial with Vibrio anguillarum

1998 • 199 citations

Prospects of using marine actinobacteria as probiotics in aquaculture

2008 • 199 citations

Production of the antibacterial substance by Bacillus sp. strain NM 12, an intestinal bacterium of Japanese coastal fish

1998 • 191 citations

The development of probiotics for the control of multiple bacterial diseases of rainbow trout, Oncorhynchus mykiss (Walbaum)

2007 • 189 citations

The effect of three strains of lactic bacteria on the production rate of rotifers, Brachionus plicatilis, and their dietary value for larval turbot, Scophthalmus maximus

1991 • 188 citations

Bacterial flora associated with a trophic chain consisting of microalgae, rotifers and turbot larvae: Influence of bacteria on larval survival

1989 • 182 citations

Administration of Probiotic Strain to Improve Sea Bream Wellness during Development

2004 • 182 citations

Probiotics for humans

1992 • 181 citations

Use of dead probiotic cells to control furunculosis in rainbow trout, Oncorhynchus mykiss (Walbaum)

2003 • 179 citations

Growth and survival of Atlantic salmon (Salmo salar) fry given diets supplemented with fish protein hydrolysate and lactic acid bacteria during a challenge trial with Aeromonas salmonicida

1995 • 173 citations

Health effects of probiotics and prebiotics A literature review on human studies

2001 • 172 citations

Gilthead seabream (Sparus aurata L.) innate immune response after dietary administration of heat-inactivated potential probiotics

2005 • 167 citations

Effect of Low pH on the Ability of Lactobacillus acidophilus to Survive and Adhere to Human Intestinal Cells

1988 • 165 citations

Disease Control in Shrimp Aquaculture with Probiotic Bacteria

1999 • 164 citations

A Review of the Functionality of Probiotics in the Larviculture Food Chain

2007 • 164 citations

Lactic acid bacterium potently induces the production of interleukin-12 and interferon-γ by mouse splenocytes

1999 • 164 citations

An evaluation of two probiotic bacterial strains, Enterococcus faecium SF68 and Bacillus toyoi, for reducing edwardsiellosis in cultured European eel, Anguilla anguilla L.

2002 • 161 citations

Untitled

1997 • 161 citations

Protection of rainbow trout (Oncorhynchus mykiss) from lactococcosis by probiotic bacteria

2007 • 159 citations

Saccharomyces boulardiistimulates sIgA production and the phagocytic system of gnotobiotic mice

2000 • 158 citations

The gut-associated lymphoid tissue (GALT) of carp (Cyprinus carpio L.): An immunocytochemical analysis

1993 • 154 citations

Chapter 1 Understanding the Mechanisms by Which Probiotics Inhibit Gastrointestinal Pathogens

2009 • 154 citations

Cytokine expression in leucocytes and gut cells of rainbow trout, Oncorhynchus mykiss Walbaum, induced by probiotics

2006 • 153 citations

Effects of a Bacterial Inoculum in Channel Catfish Ponds

1998 • 153 citations

Effects of administration of probiotic strains on GALT of larval gilthead seabream: Immunohistochemical and ultrastructural studies

2006 • 152 citations

Enhanced resistance of rainbow trout, Oncorhynchus mykiss (Walbaum), against Yersinia ruckeri challenge following oral administration of Bacillus subtilis and B. licheniformis (BioPlus2B)

2003 • 148 citations

Influence of probiotic feeding duration on disease resistance and immune parameters in rainbow trout

2009 • 146 citations

In vivo imaging and genetic analysis link bacterial motility and symbiosis in the zebrafish gut

2007 • 145 citations

Evaluation of Immunomodulatory Effects of Lactic Acid Bacteria in Turbot (Scophthalmus maximus)

2002 • 144 citations

Effect of heat-inactivated fish and non-fish derived probiotics on the innate immune parameters of a teleost fish (Sparus aurata L.)

2006 • 141 citations

Evidence for the competitive exclusion of Aeromonas salmonicida from fish with stress‐inducible furunculosis by a fluorescent pseudomonad

1993 • 139 citations

Immunostimulation in the rainbow trout (Oncorhynchus mykiss) following intraperitoneal administration of Ergosan

2002 • 138 citations

Effect of dietary administration of probiotics on growth and intestine functionality of juvenile Senegalese sole (Solea senegalensis, Kaup 1858)

2008 • 134 citations

Immunological importance of the second gut segment of carp. I. Uptake and processing of antigens by epithelial cells and macrophages

1989 • 130 citations

Validation of a food frequency questionnaire for nutritional calcium intake assessment in Italian women

2002 • 126 citations

Adhering heat-killed human Lactobacillus acidophilus, strain LB, inhibits the process of pathogenicity of diarrhoeagenic bacteria in cultured human intestinal cells.

1993 • 125 citations

Trial of probiotics to prevent the vertebral column compression syndrome in rainbow trout (Oncorhynchus mykiss Walbaum)

2005 • 124 citations

Effect of Probiotics, Yeast, Vitamin E and Vitamin C Supplements on Performance and Immune Response of Laying Hen During High Environmental Temperature

2007 • 123 citations

Microbial intervention for better fish health in aquaculture: the Indian scenario

2007 • 119 citations

Response to soy: T‐cell‐like reactivity in the intestine of Atlantic salmon, Salmo salar L.

2007 • 116 citations

Enhancement of resistance to vibriosis in rainbow trout, Oncorhynchus mykiss (Walbaum), by oral administration of Clostridium butyricum bacterin

1995 • 115 citations

Adhesion to sole, Solea senegalensis Kaup, mucus of microorganisms isolated from farmed fish, and their interaction with Photobacterium damselae subsp. piscicida

2005 • 113 citations

Gnotobiotic Mouse Immune Response Induced byBifidobacteriumsp. Strains Isolated from Infants

2007 • 112 citations

Effects of two closely related probiotics on respiratory burst activity of Senegalese sole (Solea senegalensis, Kaup) phagocytes, and protection against Photobacterium damselae subsp. piscicida

2009 • 110 citations

Screening of Intestinal Microflora for Effective Probiotic Bacteria

2001 • 105 citations

Efficacy of in-feed probiotics againstAeromonas bestiarumandIchthyophthirius multifiliisskin infections in rainbow trout (Oncorhynchus mykiss, Walbaum)

2008 • 104 citations

Effect of the oral administration of Lactobacillus brevis subsp. coagulans on interferon-alpha producing capacity in humans.

1996 • 101 citations

Comparative study between probiotic bacterium Arthrobacter XE-7 and chloramphenicol on protection of Penaeus chinensis post-larvae from pathogenic vibrios

2005 • 100 citations

The adjuvant effect of yogurt on production of gamma-interferon by con a-stimulated human peripheral blood lymphocytes

1986 • 99 citations

A Probiotic <i>Lactobacillus</i> Strain Can Acquire Vancomycin Resistance during Digestive Transit in Mice

2007 • 98 citations

Assessing the use of a dietary probiotic/prebiotic as an enhancer of spinefoot rabbitfish Siganus rivulatus survival and growth

2007 • 96 citations

Relationship between number of bacteria and their probiotic effects

2008 • 94 citations

Immune responses and enhanced disease resistance in Chinese drum, Miichthys miiuy (Basilewsky), after oral administration of live or dead cells of Clostridium butyrium CB2

2008 • 94 citations

Probiotics and the Immune Response

2006 • 94 citations

Lactic acid bacteria, probiotics and immune system

2002 • 93 citations

Immunostimulatory activity ofBacillusspores

2008 • 90 citations

Surface Attachment Induced Production of Antimicrobial Compounds by Marine Epiphytic Bacteria Using Modified Roller Bottle Cultivation

2002 • 83 citations

Bifidobacterium Lactis sp. 420 Up-Regulates Cyclooxygenase (Cox)-1 and Down-Regulates Cox-2 Gene Expression in a Caco-2 Cell Culture Model

2005 • 79 citations

The significance of chitinolytic enzymes and lysozyme in rainbow trout (Salmo gairdneri) defence

1986 • 77 citations

Effect of Probiotic Bacteria on Induction and Maintenance of Oral Tolerance to β-Lactoglobulin in Gnotobiotic Mice

2003 • 76 citations

Partial decontamination of rotifers with ultraviolet radiation: the effect of changes in the bacterial load and flora of rotifers on mortalities in start-feeding larval turbot

1999 • 75 citations

Expression of lymphocyte antigenic determinants in developing gut-associated lymphoid tissue of the sea bass Dicentrarchus labrax (L.)

1997 • 75 citations

Isolation of Bacteriocin Producing Lactic Acid Bacteria from Fish Gut and Probiotic Activity Against Common Fresh Water Fish Pathogen Aeromonas hydrophila

2008 • 74 citations

Immune modulation by probiotic strains: Quantification of phagocytosis of Aeromonas salmonicida by leukocytes isolated from gut of rainbow trout (Oncorhynchus mykiss) using a radiolabelling assay

2006 • 73 citations

Assessment of a new synbiotic preparation in healthy volunteers: survival, persistence of probiotic strains and its effect on the indigenous flora

2003 • 73 citations

Relationship between number of bacteria and their probiotic effects

2008 • 69 citations

Immunopurification of T-cells from sea bass Dicentrarchus labrax (L.)

2000 • 66 citations

Selection of probiotics by various inhibition test methods for use in the culture of western king prawns, Penaeus latisulcatus (Kishinouye)

2007 • 60 citations

Isolation of Putative Probionts from the Intestines of Indian Major Carps

2007 • 57 citations

Immunological differences in intestine and rectum of Atlantic cod (Gadus morhua L.)

2009 • 56 citations

Effect of <i>Lactococcus lactis</i> CLFP 100 and<i> Leuconostoc mesenteroides</i> CLFP 196 on <i>Aeromonas salmonicida </i>Infection in Brown Trout <i>(Salmo trutta)</i>

2009 • 55 citations

Effect of Orally Administered Non‐Viable Lactobacillus Cells on Murine Humoral Immune Responses

2005 • 54 citations

Compartmentalisation of T cells expressing CD8α and TCRβ in developing thymus of sea bass Dicentrarchus labrax (L.)

2007 • 53 citations

Interference of Listonella anguillarum with potential probiotic microorganisms isolated from farmed gilthead seabream (Sparus aurata, L.)

2005 • 51 citations

Effect of Dietary Supplementation of Biogen® (Commercial Probiotic) on Mono-Sex Nile tilapia Oreochromis niloticus under Different Stocking Densities

2009 • 51 citations

Differential effects of two probiotic strains with different bacteriological properties on intestinal gene expression, with special reference to indigenous bacteria

2007 • 50 citations

Effect of germ-free rearing environment on gut development of larval sea bass (Dicentrarchus labrax L.)

2009 • 48 citations

Soybean meal‐induced uptake block in Atlantic salmon Salmo salar distal enterocytes

2008 • 41 citations

Pathways of bacterial contamination during egg incubation and larval rearing of turbot, Scophthalmus maximus

1994 • 41 citations

Bacteriocin activity and probiotic activity of Aeromonas media

1998 • 40 citations

Immunostimulation of larvae and juveniles of cod, Gadus morhua L.

2006 • 39 citations

Anal immunisation of carp and rainbow trout with different fractions of aVibrio anguillarumbacterin

1996 • 37 citations

Effects of dietary supplementation of commercial human probiotic and antibiotic on the growth rate and content of intestinal microflora in ornamental fishes

2007 • 36 citations

Effects of Probiotic Bacteria as Dietary Supplements on Growth and Disease Resistance in Young Channel Catfish,Ictalurus punctatus(Rafinesque)

2007 • 35 citations

Diet and Human Immune Function

2004 • 34 citations

Majority of TcRβ+ T-lymphocytes located in thymus and midgut of the bony fish, Dicentrarchus labrax (L.)

2007 • 34 citations

Influence of high-M alginate on the growth and survival of Atlantic cod (Gadus morhua L.) and spotted wolffish (Anarhichas minor Olafsen) fry

2005 • 30 citations

Non-specific Immune Response of Rainbow Trout (Oncorhynchus Mykiss) by Dietary Heat-inactivated Potential Probiotics

2008 • 30 citations

Probiotics as alternative to antimicrobials: limitations and potential.

2006 • 29 citations

Effect of Commercial Aquaculture Probiotic and Fish Gut Antagonistic Bacterial Flora on the Growth and Disease Resistance of Ornamental Fishes Carassius auratus and Xiphophorus helleri.

2008 • 28 citations

Probiotics in aquaculture

2003 • 22 citations

Partial purification of extracellular substance of Vibrio anguillarum toxigenic for rainbow trout and mouse.

1985 • 21 citations

Horizontal gene transfer in the gut: Is it a risk?

2009 • 20 citations

Uptake and transport of ferritin in the epithelium of carp () and the possible immunological implications

1985 • 19 citations

Immunomodulation and anticancer potentials of yogurt probiotic

2008 • 12 citations

Diet and Human Immune Function

2004 • 9 citations

Probiotics and Immunomodulation

2010 • 7 citations

Deleted Work

1955 • 0 citations