Probiotics: an overview of beneficial effects.

Hay fever, hygiene, and household size.

1989 • 4,910 citations

Probiotics in man and animals

1989 • 4,002 citations

Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial

2001 • 2,461 citations

Functional food science and gastrointestinal physiology and function

1998 • 1,434 citations

Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing

2001 • 1,248 citations

The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction.

1997 • 1,088 citations

Probiotics: effects on immunity

2001 • 1,019 citations

Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus

1994 • 998 citations

Probiotics in the management of atopic eczema

2000 • 995 citations

Probiotics: A novel approach in the management of food allergy☆☆☆★★★

1997 • 937 citations

Enhancement of the Circulating Antibody Secreting Cell Response in Human Diarrhea by a Human Lactobacillus Strain

1992 • 718 citations

Saccharomyces boulardii in maintenance treatment of Crohn's disease.

2000 • 698 citations

Lactobacillus GG Administered in Oral Rehydration Solution to Children with Acute Diarrhea: A Multicenter European Trial

2000 • 681 citations

Effect of long term consumption of probiotic milk on infections in children attending day care centres: double blind, randomised

2001 • 635 citations

Prevention of antibiotic-associated diarrhea by Saccharomyces boulardii: A prospective study

1989 • 581 citations

Emerging Role of Lactobacilli in the Control and Maintenance of the Vaginal Bacterial Microflora

1990 • 554 citations

Probiotics: how should they be defined?

1999 • 535 citations

A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome

2001 • 496 citations

Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders.

1974 • 483 citations

Non-pathogenic bacteria elicit a differential cytokine response by intestinal epithelial cell/leucocyte co-cultures

2000 • 460 citations

Oral probiotics can resolve urogenital infections

2001 • 452 citations

Interleukin‐10 generation in atopic children following oral Lactobacillus rhamnosus GG

2000 • 432 citations

Is Lactobacillus GG Helpful in Children With Crohn’s Disease? Results of a Preliminary, Open-Label Study

2000 • 431 citations

Modulation of a specific humoral immune response and changes in intestinal flora mediated through fermented milk intake

1994 • 430 citations

Quality assurance criteria for probiotic bacteria

2001 • 427 citations

The Health Effects of Cultured Milk Products with Viable and Non-viable Bacteria

1998 • 425 citations

Crohn's Disease and Escherichia coli

1997 • 405 citations

The effect of consumption of milk fermented by Lactobacillus casei strain Shirota on the intestinal microflora and immune parameters in humans

1998 • 396 citations

Preventive Effect of a Lactobacillus casei Preparation on the Recurrence of Superficial Bladder Cancer in a Double-Blind Trial

1995 • 371 citations

Clinical uses of probiotics for stabilizing the gut mucosal barrier: successful strains and future challenges

1996 • 348 citations

Diet and cancer prevention

2001 • 339 citations

The Role of Intestinal Gas in Functional Abdominal Pain

1975 • 324 citations

Bacteriotherapy with Lactobacillus reuteri in rotavirus gastroenteritis

1997 • 323 citations

Health benefits of probiotics

1998 • 321 citations

Ingestion of Yogurt Containing Lactobacillus acidophilus as Prophylaxis for Candidal Vaginitis

1992 • 300 citations

Probiotics in human disease

2001 • 295 citations

Viable versus inactivated lactobacillus strain GG in acute rotavirus diarrhoea.

1995 • 288 citations

Importance of intestinal colonisation in the maturation of humoral immunity in early infancy: a prospective follow up study of healthy infants aged 0-6 months

2000 • 279 citations

Regulatory T cells and inflammatory bowel disease

1999 • 270 citations

Probiotic agents to protect the urogenital tract against infection

2001 • 266 citations

The role of probiotic bacteria in cancer prevention

2000 • 263 citations

Molecular and cellular aspects of the secretory immunoglobulin system*

1995 • 261 citations

Review of probiotics available to modify gastrointestinal flora

1999 • 252 citations

Favourable effect of an acidified milk (LC-1) on Helicobacter pylori gastritis in man

2001 • 217 citations

Effects of probiotic administration upon the composition and enzymatic activity of human fecal microbiota in patients with irritable bowel syndrome or functional diarrhea

2001 • 190 citations

Effects of a Fermented Milk Drink ContainingLactobacillus caseiStrain Shirota on the Immune System in Healthy Human Subjects

2000 • 188 citations

Down‐Regulation of Anti‐CD3 Antibody‐Induced IL‐4 Production by Bovine Caseins Hydrolysed with Lactobacillus GG‐Derived Enzymes

1996 • 180 citations

Attachment of Lactobacillus casei strain GG to human colon carcinoma cell line Caco-2: comparison with other dairy strains

1991 • 154 citations

Flow Cytometric Assessment of Viability of Lactic Acid Bacteria

2001 • 154 citations

Global progress in the control of diarrheal diseases

1990 • 150 citations

Influence of three-day antimicrobial therapy and lactobacillus vaginal suppositories on recurrence of urinary tract infections.

1992 • 139 citations

Adhesion of fourBifidobacteriumstrains to human intestinal mucus from subjects in different age groups

1999 • 134 citations

Handbook of Probiotics

1999 • 122 citations

Microbial colonization influences composition and T‐cell receptor Vβ repertoire of intraepithelial lymphocytes in rat intestine

1996 • 119 citations

Chemical, physical and enzymatic pre-treatments of probiotic lactobacilli alter their adhesion to human intestinal mucus glycoproteins

2000 • 117 citations

Probiotics: towards demonstrating efficacy

1999 • 114 citations

Determination of Complement-Mediated Killing of Bacteria by Viability Staining and Bioluminescence

1998 • 112 citations

Resected Human Colonic Tissue: New Model for Characterizing Adhesion of Lactic Acid Bacteria

2002 • 98 citations

Prophylactic Efficacy of Lactobacilli on Traveler’s Diarrhea

1989 • 98 citations

Effect of lactic acid producing bacteria on the human intestinal microflora during ampicillin treatment

1991 • 92 citations

Diet during Rotavirus Enteritis Affects Jejunal Permeability to Macromolecules in Suckling Rats

1993 • 89 citations

Effects of Lactobacillus GG Yogurt on Human Intestinal Microecology in Japanese Subjects

1996 • 85 citations

A randomized clinical trial of the effect of yoghurt on the human salivary microflora

2001 • 74 citations

Cytokine‐Induced Alteration of the Epithelial Barrier to Food Antigens in Disease

2000 • 68 citations

Recovery ofLactobacillusStrain GG (ATCC 53103) from Saliva of Healthy Volunteers after Consumption of Yoghurt Prepared with the Bacterium

1994 • 67 citations

Suppression of T-cell activation by Lactobacillus rhamnosus GG-degraded bovine casein

2001 • 67 citations

Probiotic supplementation to enhance natural immunity in the elderly: effects of a newly characterized immunostimulatory strain Lactobacillus rhamnosus HN001 (DR20™) on leucocyte phagocytosis

2001 • 55 citations

The effect of unabsorbed sucrose and mannitol on the small intestinal flow rate and mean transit time.

1968 • 53 citations

The Effect of Digestive Enzymes on the Adhesion of Probiotic Bacteria In Vitro

2001 • 49 citations

Horseradish peroxidase transport across rabbit jejunum and Peyer's patches in vitro

1983 • 46 citations

Disease-Dependent Adhesion of Lactic Acid Bacteria to the Human Intestinal Mucosa

2003 • 46 citations

Protective effect of intranasally inoculatedLactobacillus fermentumagainstStreptococcus pneumoniaechallenge on the mouse respiratory tract

2001 • 43 citations

Probiotics and gut inflammation

1999 • 36 citations

Adriamycin-induced antitumor response in lethally irradiated mice

1979 • 26 citations

Disaccharidase Activities of the Atrophic Gastric Mucosa with Intestinal Metaplasia

1968 • 26 citations

Pathogenesis of gut virus infection

1990 • 22 citations

Microflora of Patients with Stool Abnormality

1984 • 16 citations

Introduction

2001 • 8 citations