Transferrin receptor 1 mRNA is downregulated in placenta of hepcidin transgenic embryos

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O ₂ -Regulated Prolyl Hydroxylation

2001 • 5,255 citations

A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload

2001 • 1,673 citations

Balancing Acts

2004 • 1,663 citations

Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter

2000 • 1,624 citations

Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation

2003 • 1,516 citations

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

2002 • 1,414 citations

A Novel Duodenal Iron-Regulated Transporter, IREG1, Implicated in the Basolateral Transfer of Iron to the Circulation

2000 • 1,413 citations

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

2003 • 1,392 citations

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress.

1996 • 1,311 citations

A Novel Mammalian Iron-regulated Protein Involved in Intracellular Iron Metabolism

2000 • 1,259 citations

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 ( USF2 ) knockout mice

2001 • 1,212 citations

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

2002 • 1,167 citations

Severe iron deficiency anemia in transgenic mice expressing liver hepcidin

2002 • 888 citations

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

2002 • 872 citations

Desferrioxamine induces erythropoietin gene expression and hypoxia- inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction

1993 • 740 citations

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

2004 • 390 citations

Identification of a Hypoxia Response Element in the Transferrin Receptor Gene

1999 • 359 citations

Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats

2002 • 340 citations

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

2003 • 312 citations

Effect of hepcidin on intestinal iron absorption in mice

2004 • 226 citations

Effect of iron deficiency on placental transfer of iron and expression of iron transport proteins in vivo and in vitro

2001 • 159 citations

Identification and Localization of Divalent Metal Transporter-1 (DMT-1) in Term Human Placenta

2000 • 113 citations

Effect of iron deficiency on placental transfer of iron and expression of iron transport proteins in vivo and in vitro

2001 • 110 citations

H ferritin knockout mice: a model of hyperferritinemia in the absence of iron overload

2001 • 87 citations

Increased Placental Iron Regulatory Protein-1 Expression in Diabetic Pregnancies Complicated by Fetal Iron Deficiency

1999 • 40 citations

Molecular and Cellular Iron Transport

2002 • 35 citations

The role of the placenta in iron transfer from mother to fetus and the relationship between iron status and fetal outcome.

2003 • 31 citations

Role of Ets-1 in transcriptional regulation of transferrin receptor and erythroid differentiation

2002 • 28 citations