Treatment strategies for patients with recurrent brain tumors

Dose, time and fractionation: A clinical hypothesis

1969 • 615 citations

Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas

1991 • 485 citations

Thermally Enhanced Radioresponse of Cultured Chinese Hamster Cells: Inhibition of Repair of Sublethal Damage and Enhancement of Lethal Damage

1974 • 375 citations

Chemotherapy for malignant gliomas

1988 • 343 citations

Reoperation for Recurrent Glioblastoma and Anaplastic Astrocytoma

1987 • 250 citations

Use of thallium-201 SPECT to quantitate malignancy grade of gliomas

1989 • 224 citations

Thallium-201 brain tumor imaging: a comparative study with pathologic correlation.

1987 • 223 citations

PET of malignant cerebral tumors after interstitial brachytherapy

1988 • 216 citations

Reoperation in the treatment of recurrent intracranial malignant gliomas

1987 • 209 citations

Brachytherapy of recurrent malignant brain tumors with removable high-activity iodine-125 sources

1984 • 204 citations

Immunobiology of primary intracranial tumors

1977 • 191 citations

A commentary on the biology and growth kinetics of low-grade and high-grade gliomas

1984 • 159 citations

Positron Emission Tomography in the Detection of Malignant Degeneration of Low-Grade Gliomas

1989 • 136 citations

Effect of Age and Reoperation on Survival in the Combined Modality Treatment of Malignant Astrocytoma

1982 • 102 citations

Interstitial microwave hyperthermia for brain tumors

1983 • 102 citations

Chemotherapy of Primary Brain Tumors

1985 • 99 citations

Immunobiology of primary intracranial tumors

1985 • 83 citations

Thallium-201 tumor/cardiac ratio estimation of residual astrocytoma

1988 • 75 citations

High-dose multi-agent chemotherapy followed by bone marrow ‘rescue’ for malignant astrocytomas of childhood and adolescence

1990 • 72 citations

Interstitial chemotherapy for brain tumors: review

1991 • 72 citations

Procarbazine chemotherapy in the treatment of recurrent malignant astrocytomas after radiation and nitrosourea failure

1990 • 72 citations

Polyamine Depletion Influences Drug-Induced Chromosomal Damage

1982 • 67 citations

Hyperthermia and Low Dose-Rate Irradiation

1978 • 65 citations

The role of energy in hyperthermia‐induced mammalian cell inactivation: A study of the effects of glucose starvation and an uncoupler of oxidative phosphorylation

1981 • 61 citations

Interstitial irradiation and hyperthermia for the treatment of recurrent malignant brain tumors

1991 • 61 citations

Treatment of patients with recurrent primary brain tumors with AZQ

1984 • 56 citations

Interstitial Irradiation and Hyperthermia for the Treatment of Recurrent Malignant Brain Tumors

1991 • 54 citations

Treatment of Recurrent Gliomas with 1,3-Bis(2-Chloroethyl)-1-Nitrosourea and A-Difluoromethylornithine

1989 • 41 citations

Phase I-II study of eflornithine and mitoguazone combined in the treatment of recurrent primary brain tumors.

1987 • 39 citations

Localized 31P magnetic resonance spectroscopy of large pediatric brain tumors

1990 • 27 citations

Phase II trial of Serratia marcescens extract in recurrent malignant astrocytoma.

1990 • 24 citations

Iridium-192 Brachytherapy in Combination with Interstitial Microwave-Induced Hyperthermia for Malignant Glioma

1987 • 21 citations

Differential response to 1,3‐bis (2‐chloroethyl)‐1‐nitrosourea in drug‐resistant and ‐sensitive 9L rat brain tumor cells pretreated with α‐difluoromethylornithine and 6‐thioguanine

1989 • 21 citations

Intravenous BCNU and AZQ in patients with recurrent malignant gliomas

1989 • 20 citations

In Vivo Magnetic Resonance Imaging and ³¹P Spectroscopy of Large Human Brain Tumours at 1.5 Tesla

1988 • 20 citations

Phase 11 study of aziridinylbenzoquinone (AZQ: NSC-182986) in the treatment of malignant gliomas recurrent after radiation

1985 • 14 citations

Application of invasive microwave hyperthermia for the treatment of gliomas

1988 • 9 citations