Magnetic Resonance Spectroscopy in Affective Disorders

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

ATP and Brain Function

1989 • 812 citations

A review of chemical issues in ¹H NMR spectroscopy: N‐acetyl‐l‐aspartate, creatine and choline

1991 • 656 citations

Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation.

1991 • 592 citations

Cerebral intracellular pH by ³¹ P nuclear magnetic resonance spectroscopy

1985 • 516 citations

Alterations in Brain High-Energy Phosphate and Membrane Phospholipid Metabolism in First-Episode, Drug-Naive Schizophrenics

1991 • 481 citations

N -Acetylaspartate in neuropsychiatric disorders

1995 • 422 citations

Effect of Photic Stimulation on Human Visual Cortex Lactate and Phosphates Using¹H and³¹P Magnetic Resonance Spectroscopy

1992 • 406 citations

Resolution enhancement of protein PMR spectra using the difference between a broadened and a normal spectrum

1973 • 349 citations

[Clinical applications of magnetic resonance spectroscopy].

1988 • 239 citations

Alterations in brain phosphorous metabolism in bipolar disorder detected by in vivo 31P and 7Li magnetic resonance spectroscopy

1993 • 227 citations

Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy

1994 • 219 citations

Patterns of maternal transmission in bipolar affective disorder.

1995 • 216 citations

NMR Studies of Intracellular Metal Ions in Intact Cells and Tissues

1984 • 214 citations

An In Vivo Study of the Prefrontal Cortex of Schizophrenic Patients at Different Stages of Illness via Phosphorus Magnetic Resonance Spectroscopy

1995 • 203 citations

Brain phosphorous metabolism in depressive disorders detected by phosphorus-31 magnetic resonance spectroscopy

1992 • 200 citations

Altered platelet protein kinase C activity in bipolar affective disorder, manic episode

1993 • 197 citations

Human brain fluoxetine concentrations

1993 • 197 citations

Human cerebral osmolytes during chronic hyponatremia. A proton magnetic resonance spectroscopy study.

1995 • 195 citations

Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1T

1994 • 191 citations

P‐31 Nuclear Magnetic Resonance Analysis of Brain: The Perchloric Acid Extract Spectrum

1982 • 164 citations

31P Nuclear Magnetic Resonance Studies of Phosphoglyceride Metabolism in Developing and Degenerating Brain

1987 • 158 citations

Abnormal frontal lobe phosphorous metabolism in bipolar disorder

1995 • 155 citations

What might be the impact on neurology of the analysis of brain metabolism by in vivo magnetic resonance spectroscopy?

1994 • 148 citations

Proton magnetic resonance spectroscopy of the brain in schizophrenic and affective patients

1992 • 148 citations

Brain choline in depression: In vivo detection of potential pharmacodynamic effects of antidepressant therapy using hydrogen localized spectroscopy

1994 • 142 citations

Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study.

1995 • 133 citations

Phosphorus-31 magnetic resonance spectroscopy and ventricular enlargement in bipolar disorder

1994 • 124 citations

Decreased temporal lobe phosphomonoesters in bipolar disorder

1995 • 119 citations

Proton magnetic resonance spectroscopy investigation of hyperventilation in subjects with panic disorder and comparison subjects

1995 • 114 citations

Lateralized abnormality of high energy phosphate metabolism in the frontal lobes of patients with bipolar disorder detected by phase-encoded³¹P-MRS

1995 • 114 citations

Study of chronic schizophrenics using ³¹P magnetic resonance chemical shift imaging

1992 • 107 citations

Phosphorylethanolamine ‐ the major constituent of the phosphomonoester peak observed by ³¹P‐NMR on developing dog brain

1984 • 103 citations

Initial Observations on Effect of Vigabatrin on In Vivo ¹H Spectroscopic Measurements of γ‐Aminobutyric Acid, Glutamate, and Glutamine in Human Brain

1995 • 100 citations

Choline-containing compounds detected by proton magnetic resonance spectroscopy in the basal ganglia in bipolar disorder.

1996 • 99 citations

31Phosphorus magnetic resonance spectroscopy of the frontal and parietal lobes in chronic schizophrenia

1994 • 96 citations

Measurement of brain phosphoinositide metabolism in bipolar patients using in vivo 31P-MRS

1991 • 95 citations

¹H and ³¹P NMR measurement of cerebral lactate, high‐energy phosphate levels, and pH in humans during voluntary hyperventilation: associated EEG, capnographic, and doppler findings

1989 • 94 citations

Accumulation of fluoxetine and norfluoxetine in human brain during therapeutic administration

1992 • 88 citations

In vivo measurement of lithium in humans by nuclear magnetic resonance spectroscopy

1988 • 86 citations

Na+/H+ exchange is the major mechanism of pH regulation in cultured sympathetic neurons: Measurements in single cell bodies and neurites using a fluorescent pH indicator

1987 • 82 citations

A method for volume-localized lactate editing using zero-quantum coherence created in a stimulated-echo pulse sequence

1988 • 79 citations

Correlations of phosphomonoesters measured by phosphorus-31 magnetic resonance spectroscopy in the frontal lobes and negative symptoms in schizophrenia

1994 • 75 citations

In Vivo Assessment of Free Magnesium Concentration in Human Brain by31P MRS. A New Calibration Curve Based on a Mathematical Algorithm

1996 • 75 citations

Nuclear magnetic resonance spectroscopic analysis of myo-inositol phosphates including inositol 1,3,4,5-tetrakisphosphate.

1986 • 73 citations

Choline in the treatment of rapid-cycling bipolar disorder: Clinical and neurochemical findings in lithium-treated patients

1996 • 73 citations

Lateralized abnormality of high-energy phosphate and bilateral reduction of phosphomonoester measured by phosphorus-31 magnetic resonance spectroscopy of the frontal lobes in schizophrenia

1995 • 69 citations

Magnetic resonance spectroscopy in psychiatry: potential, pitfalls, and promise [published erratum appears in Am J Psychiatry 1992 Mar;149(3):431]

1991 • 67 citations

Assessment of absolute metabolite concentrations in human tissue by³¹P MRS invivo. Part I: Cerebrum, cerebellum, cerebral gray and white matter

1994 • 66 citations

In Vivo NMR spectroscopy of lithium‐7 in humans

1990 • 61 citations

Applications of magnetic resonance spectroscopy to the investigation of neuropsychiatric disorders.

1992 • 61 citations

Brain lithium concentration by 7Li- and 1H-magnetic resonance spectroscopy in bipolar disorder

1992 • 60 citations

31P-NMR study of brain phospholipid structures in vivo

1991 • 58 citations

Measurement of tissue lithium concentration by lithium magnetic resonance spectroscopy in patients with bipolar disorder

1991 • 57 citations

24-Hour lithium concentration in human brain studied by Li-7 magnetic resonance spectroscopy

1994 • 57 citations

Variability of brain lithium levels during maintenance treatment: A magnetic resonance spectroscopy study

1995 • 57 citations

Mapping creatine kinase reaction rates in human brain and heart with 4 tesla saturation transfer 31P NMR

1992 • 57 citations

Proton magnetic resonance spectroscopy of basal ganglia in chronic schizophrenia

1996 • 56 citations

Cerebral Lactate Elevation by Electroshock: A 1H Magnetic Resonance Studya

1987 • 55 citations

Brain lithium concentrations measured with lithium-7 magnetic resonance spectroscopy in patients with affective disorders: Relationship to erythrocyte and serum concentrations

1993 • 46 citations

Frontal lobe phosphorus metabolism and neuropsychological function in aging and in alzheimer's disease

1995 • 46 citations

Lithium side effects in relation to brain lithium concentration measured by lithium-7 magnetic resonance spectroscopy

1996 • 46 citations

The human brain resonance of choline-containing compounds is similar in patients receiving lithium treatment and controls: An in vivo proton magnetic resonance spectroscopy study

1992 • 46 citations

Proton magnetic resonance spectroscopy of the basal ganglia in patients with schizophrenia: a preliminary report

1996 • 45 citations

Creatinine and creatine in CSF: indices of brain energy metabolism in depression

1988 • 45 citations

Relationship of lithium concentrations in the brain measured by lithium-7 magnetic resonance spectroscopy to treatment response in mania.

1994 • 44 citations

Nuclear magnetic resonance spectroscopy: A review of neuropsychiatric applications

1995 • 44 citations

Lithium levels in monkey and human brain after chronic, therapeutic, oral dosage

1976 • 43 citations

Changes in the 31P-NMR spectra of cats receiving lithium chloride systemically

1986 • 42 citations

Effect of photic stimulation on energy metabolism in the human brain measured by 31P-MR spectroscopy

1996 • 42 citations

Deletion of leukocyte mitochondrial DNA in bipolar disorder

1996 • 42 citations

Chemical assessment of phospholipid and phosphoenergetic metabolites in regenerating rat liver measured by in vivo and in vitro 31P-NMR

1992 • 42 citations

Measurement of human brain lithium in vivo by MR spectroscopy.

1993 • 40 citations

Fluoxetine and trifluoperazine in human brain: A 19F-nuclear magnetic resonance spectroscopy study

1992 • 40 citations

Investigation of broad resonances in ³¹P NMR spectra of the human brain in vivo

1994 • 40 citations

Mitochondrial encephalomyopathy

1994 • 39 citations

In vivo 7Li nuclear magnetic resonance study of lithium pharmacokinetics and chemical shift imaging in psychiatric patients

1993 • 37 citations

Basal ganglia phosphorous metabolism in chronic schizophrenia

1995 • 34 citations

Chronic lithium does not alter human myo-inositol or phosphomonoester concentrations as measured by 1H and 31P MRS

1996 • 34 citations

Nmr Spectroscopy in Psychiatric Brain Disorders

1995 • 33 citations

In vivo⁷Li NMR imaging and localized spectroscopy of rat brain

1992 • 32 citations

High-energy phosphate metabolism in the frontal lobes of patients with panic disorder detected by phase-encoded 31P-MRS

1996 • 32 citations

Quantitative ³¹P MRS of the normal adult human brain. Assessment of interindividual differences and ageing effects

1993 • 31 citations

Chronic Li+ attenuates agonist- and phorbol ester-mediated Na+/H+ antiporter activity in HL-60 cells

1990 • 31 citations

Localized magnetic resonance spectroscopy measurement of brain lactate during intravenous lactate infusion in healthy volunteers

1992 • 29 citations

Relaxation and imaging of lithium in vivo

1986 • 28 citations

In vivo ¹H spectroscopy of the human brain following electroconvulsive therapy

1990 • 27 citations

In vivo³¹P NMR spectroscopy of agonist‐stimulated phosphatidylinositol metabolism in cat brain

1987 • 27 citations

In Vivo Magnetic Resonance Spectroscopy: Applications in Psychiatry

1995 • 26 citations

Proton mrs of the basal ganglia in bipolar disorder

1994 • 26 citations

Brain fluoxetine measurements using fluorine magnetic resonance spectroscopy in patients with social phobia

1995 • 25 citations

Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study

1995 • 24 citations

Chronic regulation of the Na/H antiporter.

1993 • 24 citations

The neuropathologic basis of major affective disorders: neuroanatomic insights

1994 • 24 citations

Competition between Li⁺ and Mg²⁺ for ATP in human erythrocytes A ³¹P NMR and optical spectroscopy study

1989 • 22 citations

Relationship of Lithium Concentrations

1994 • 21 citations

Proton mrs of the basal ganglia in major depression

1994 • 20 citations

Localized proton and phosphorus magnetic resonance spectroscopy following electroconvulsive therapy

1993 • 20 citations

1H NMR Studies of Human Brain Metabolism and Physiology

1994 • 20 citations

Relaxation times and concentrations of ⁷Li in the brain of patients receiving Lithium therapy

1993 • 19 citations

Phosphorus-31 magnetic resonance spectroscopic observations in 4 cases with anorexia nervosa

1997 • 18 citations

Alterations in membrane molecular dynamics in erythrocytes of patients with affective illness

1993 • 11 citations