Transforming Growth Factor-β Differentially Inhibits MyD88-dependent, but Not TRAM- and TRIF-dependent, Lipopolysaccharide-induced TLR4 Signaling

Smad-dependent and Smad-independent pathways in TGF-β family signalling

2003 • 5,052 citations

The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction

2002 • 4,069 citations

Toll-like receptors in innate immunity

2004 • 3,233 citations

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

1992 • 2,969 citations

Role of Transforming Growth Factor β in Human Disease

2000 • 2,405 citations

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

1993 • 1,941 citations

Inferences, questions and possibilities in Toll-like receptor signalling

2004 • 1,458 citations

HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line

1992 • 1,258 citations

Cutting Edge: Repurification of Lipopolysaccharide Eliminates Signaling Through Both Human and Murine Toll-Like Receptor 2

2000 • 1,173 citations

New insights into TGF-β–Smad signalling

2004 • 1,169 citations

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

2004 • 987 citations

Epoxomicin, a potent and selective proteasome inhibitor, exhibitsin vivoantiinflammatory activity

1999 • 914 citations

Toll-Like Receptor-4 Is Expressed by Macrophages in Murine and Human Lipid-Rich Atherosclerotic Plaques and Upregulated by Oxidized LDL

2001 • 659 citations

Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes

1999 • 610 citations

Elevated TGF-β1 Secretion and Down-Modulation of NKG2D Underlies Impaired NK Cytotoxicity in Cancer Patients

2004 • 518 citations

Inhibition of Transforming Growth Factor-β Signaling Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Mice

2001 • 474 citations

Disruption of TGF-β signaling in T cells accelerates atherosclerosis

2003 • 426 citations

Regulatory functions of ubiquitination in the immune system

2002 • 392 citations

SIGNALING PATHWAYS THAT ESTABLISH THE DORSAL-VENTRAL PATTERN OF THE DROSOPHILA EMBRYO

1995 • 348 citations

Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system

2004 • 300 citations

Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88

2004 • 294 citations

Ubiquitin Ligases and the Immune Response

2004 • 277 citations

Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88

2004 • 246 citations

Regulation of NK cell functions by TGF-beta 1.

1995 • 241 citations

Immune dysregulation in TGF-beta 1-deficient mice.

1994 • 231 citations

TLR Signaling: An Emerging Bridge from Innate Immunity to Atherogenesis

2004 • 211 citations

TGF-β: the missing link in CD4+CD25+ regulatory T cell-mediated immunosuppression

2003 • 207 citations

Identification of Distinct Signaling Pathways Leading to the Phosphorylation of Interferon Regulatory Factor 3

2001 • 193 citations

Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins

2004 • 152 citations

Infections in patients with cancer undergoing chemotherapy: aetiology, prevention, and treatment

2003 • 151 citations

Specific abrogation of transforming growth factor-β signaling in T cells alters atherosclerotic lesion size and composition in mice

2003 • 146 citations

Circulating TNF‐α, TGF‐β, and IL‐10 in Tuberculosis Patients and Healthy Contacts

2001 • 105 citations

Aberrant Toll Receptor Expression and Endotoxin Hypersensitivity in Mice Lacking a Functional TGF-β1 Signaling Pathway

2004 • 103 citations

Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis

2003 • 99 citations

TB, or not TB: that is the question – does TLR signaling hold the answer?

2004 • 63 citations

Redirection of B cell responsiveness by transforming growth factor β receptor

2003 • 51 citations

sog and dpp exert opposing maternal functions to modify Toll signaling and pattern the dorsoventral axis of the Drosophila embryo

2000 • 45 citations