Differences in vascular effects and removal of endothelin‐1 in human lung, brain, and skeletal muscle,

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1990 • 2,432 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Polar secretion of endothelin-1 by cultured endothelial cells.

1992 • 650 citations

The Body Cell Mass and Its Supporting Environment

1963 • 630 citations

Immunoreactive endothelin in human plasma: Marked elevations in patients in cardiogenic shock

1989 • 330 citations

Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs

1988 • 279 citations

Endothelin is a positive inotropic agent in human and rat heart in, vitro

1989 • 235 citations

Positive chronotropic effects of endothelin, a novel endothelium-derived vasoconstrictor peptide

1988 • 203 citations

Endothelin acts in feline and canine cerebral arteries from the adventitial side.

1989 • 138 citations

Elevated plasma levels of endothelin in patients with sepsis syndrome.

1991 • 137 citations

Tissue specific distribution, clearance and vascular effects of endothelin in the pig

1989 • 110 citations

Effects of endothelin on regional blood flows in squirrel monkeys.

1989 • 95 citations

Tone-dependent responses to endothelin in the isolated perfused fetal sheep pulmonary circulation in situ

1991 • 88 citations

Characterization of Contractile Responses to Endothelin in Human Cerebral Arteries: Implications for Cerebral Vasospasm

1990 • 80 citations

Long-lasting vasoconstriction and efficient regional extraction of endothelin-1 in human splanchnic and renal tissues

1991 • 76 citations

Regional effects and clearance of endothelin‐1 across pulmonary and splanchnic circulation

1992 • 76 citations

Characteristics of endothelin A and B binding sites and their vascular effects in pig peripheral tissues

1991 • 37 citations

Potent vasoconstrictor effects and clearance of endothelin in the human forearm

1991 • 35 citations

Regional extraction of endothelins and conversion of big endothelin to endothelin‐1 in the pig

1991 • 31 citations

Occurrence and effects of endothelin in guinea‐pig cardiopulmonary tissue

1990 • 21 citations

CIRCULATION IN SKELETAL MUSCLE

1962 • 18 citations

Phosporamidon inhibits the vasoconstrictor effects evoked by big endothelin-1 but not the elevation of plasma endothelin-1 in vivo

1991 • 15 citations