Enduring Effects of Chronic Ethanol in the CNS: Basis for Alcoholism

Drug Abuse: Hedonic Homeostatic Dysregulation

1997 • 2,472 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol.

1986 • 852 citations

Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats

1992 • 525 citations

Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro

1990 • 507 citations

Ethanol Self-Administration Restores Withdrawal-Associated Deficiencies in Accumbal Dopamine and 5-Hydroxytryptamine Release in Dependent Rats

1996 • 455 citations

Ethanol Directly Excites Dopaminergic Ventral Tegmental Area Reward Neurons

1999 • 390 citations

Electrophysiological Characterization of GABAergic Neurons in the Ventral Tegmental Area

1998 • 387 citations

Behavioral Neurobiology of Alcohol Addiction: Recent Advances and Challenges

2002 • 323 citations

Profound decrement of mesolimbic dopaminergic neuronal activity during ethanol withdrawal syndrome in rats: electrophysiological and biochemical evidence.

1993 • 308 citations

Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats

1999 • 265 citations

Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system

1995 • 222 citations

Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure.

2002 • 188 citations

Dopamine, addiction and reward

1992 • 179 citations

Neurophysiology of Dopaminergic Systems: Current Status and Clinical Perspectives

1987 • 165 citations

Long-Lasting Potentiation of GABAergic Synapses in Dopamine Neurons after a SingleIn VivoEthanol Exposure

2002 • 164 citations

The Effects of Ethanol on Dopaminergic Neurons of the Ventral Tegmental Area Studied with Intracellular Recording in Brain Slices

1998 • 143 citations

Mesolimbic dopaminergic reduction outlasts ethanol withdrawal syndrome: Evidence of protracted abstinence

1996 • 131 citations

Increased ethanol excitation of dopaminergic neurons of the ventral tegmental area after chronic ethanol treatment.

2002 • 114 citations

Effects of Concurrent Access to Multiple Ethanol Concentrations and Repeated Deprivations on Alcohol Intake of Alcohol-Preferring Rats

2001 • 113 citations

Discharge Profiles of Ventral Tegmental Area GABA Neurons during Movement, Anesthesia, and the Sleep–Wake Cycle

2001 • 106 citations

Characterization of a pentylenetetrazol-like interoceptive stimulus produced by ethanol withdrawal.

1988 • 103 citations

Adaptive responses of gamma-aminobutyric acid neurons in the ventral tegmental area to chronic ethanol.

1999 • 102 citations

Astroglial in vivo response to cocaine in mouse dentate gyrus: a quantitative and qualitative analysis by confocal microscopy

2002 • 101 citations

Increased Ethanol Excitation of Dopaminergic Neurons of the Ventral Tegmental Area After Chronic Ethanol Treatment

2002 • 100 citations

Persistent reduction of GABAA receptor-mediated inhibition in rat hippocampus after chronic intermittent ethanol treatment

1996 • 98 citations

Alteration in the Sensitivity of GABA_A Receptors to Allosteric Modulatory Drugs in Rat Hippocampus After Chronic Intermittent Ethanol Treatment

1998 • 90 citations

Drug Dependence as a Disorder of Neural Plasticity: Focus on Dopamine and Glutamate

2001 • 86 citations

Acute withdrawal after repeated ethanol treatment reduces the number of spontaneously active dopaminergic neurons in the ventral tegmental area

1993 • 73 citations

Dopaminergic Neurons in the Ventral Tegmental Area of C57BL/6J and DBA/2J Mice Differ in Sensitivity to Ethanol Excitation

2000 • 69 citations

Responses of ventral tegmental area GABA neurons to brain stimulation reward

2001 • 68 citations

Alterations in mesolimbic dopamine function during the abstinence period following chronic ethanol consumption

2001 • 64 citations

Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability

1998 • 57 citations

Enhancement of amphetamine- and cocaine-induced locomotor activity after chronic ethanol administration.

1997 • 56 citations

Effects of chronic alcohol ingestion on the mesostriatal dopamine system in the rat

2001 • 55 citations

LACK OF TOLERANCE TO ETHANOL-INDUCED STIMULATION OF MESOLIMBIC DOPAMINE SYSTEM

1992 • 54 citations

Marked decrease of A10 dopamine neuronal firing during ethanol withdrawal syndrome in rats

1992 • 53 citations

Prolonged Changes in Neurochemistry of Dopamine Neurones After Chronic Ethanol Consumption

2000 • 44 citations

Chronic Alcoholics without Wernicke‐Korsakoff Syndrome or Cirrhosis Do Not Lose Serotonergic Neurons in the Dorsal Raphe Nucleus

1996 • 32 citations

Ethanol‐Induced Suppression of Hippocampal Long‐Term Potentiation Is Blocked by Lesions of the Septohippocampal Nucleus

1993 • 30 citations

Studies on long-term potentiation of the population spike component of hippocampal field potential by the tetanic stimulation of the perforant path in rats: effects of a dopamine agonist, SKF-38393

1992 • 27 citations

Ethanol withdrawal does not induce a reduction in the number of spontaneously active dopaminergic neurons in the mesolimbic system

1995 • 26 citations

Prolonged effects of chronic ethanol treatment on responses to repeated nicotine administration: interactions with environmental cues

1999 • 19 citations

Memory-forming Chemical Reactions

2001 • 18 citations

Ethanol acts via the ventral tegmental area to influence hippocampal physiology

1994 • 18 citations

Microelectrophoretic application of SCH-23390 into the lateral septal nucleus blocks ethanol-induced suppression of LTP, in vivo, in the adult rodent hippocampus

1996 • 11 citations

Ethanol Suppression of Hippocampal Plasticity

1999 • 1 citations