Presynaptic ?2A-adrenoceptors inhibit the release of endogenous dopamine in rabbit caudate nucleus slices

Verteilung Von Noradrenalin Und Dopamin (3-Hydroxytyramin) Im Gehirn Des Menschen Und Ihr Verhalten Bei Erkrankungen Des Extrapyramidalen Systems

1960 • 1,863 citations

Modulation of neurotransmitter release by presynaptic autoreceptors

1989 • 935 citations

The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory

1972 • 812 citations

Evidence for a central noradrenaline receptor stimulation by clonidine

1970 • 550 citations

Dopamine ?Autoreceptors?: Pharmacological characterization by microiontophoretic single cell recording studies

1977 • 544 citations

Subtypes of α ₁ ‐ and α ₂ ‐adrenergic receptors

1992 • 358 citations

Presynaptic α-autoreceptors

2005 • 355 citations

Presynaptic alpha-autoreceptors.

1987 • 350 citations

Comparison of the effects of clonidine on pre-and postsynaptic adrenoceptors in the rabbit pulmonary artery

1974 • 316 citations

Effect of dopamine receptor agonists and antagonists on release of dopamine in the rabbit caudate nucleus in vitro

1978 • 242 citations

Isolation of rat genomic clones encoding subtypes of the alpha 2-adrenergic receptor. Identification of a unique receptor subtype

1991 • 220 citations

Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: A possible role for the locus coeruleus in the progression of Parkinson's disease

1991 • 211 citations

Pharmacological evidence for a stimulation of dopamine neurons by noradrenaline neurons in the brain

1976 • 179 citations

Effects of the selective adenosine A2 receptor agonist CGS 21680 on in vitro electrophysiology, cAMP formation and dopamine release in rat hippocampus and striatum.

1990 • 167 citations

Cloning of two mouse genes encoding alpha 2-adrenergic receptor subtypes and identification of a single amino acid in the mouse alpha 2-C10 homolog responsible for an interspecies variation in antagonist binding.

1992 • 160 citations

Partial agonist action of clonidine on prejunctional and postjunctional ?-adrenoceptors

1978 • 130 citations

Clonidine modulates dopamine cell firing in rat ventral tegmental area

1989 • 126 citations

Identification and characterization of alpha 2D-adrenergic receptors in bovine pineal gland.

1991 • 126 citations

Transmitter release from brain slices elicited by single pulses: a powerful method to study presynaptic mechanisms

1988 • 124 citations

Further functional in vitro comparison of pre- and postsynaptic dopamine receptors in the rabbit caudate nucleus

1983 • 121 citations

Presynaptic regulation of dopamine release in corpus striatum monitored in vitro in real time by fast cyclic voltammetry

1990 • 110 citations

Differences between the α₂‐adrenoceptor in rat submaxillary gland and the α_2A‐ and α_2B‐adrenoceptor subtypes

1989 • 103 citations

Application of fast cyclic voltammetry to measurement of electrically evoked dopamine overflow from brain slices in vitro

1990 • 98 citations

Presynaptic ?2-autoreceptors in brain cortex: ?2D in the rat and ?2A in the rabbit

1993 • 94 citations

Suppression of nigrostriatal and mesolimbic dopamine release following noradrenaline depletion by DSP-4: A microdialysis study

1992 • 84 citations

Noradrenaline, dopamine and serotonin levels and metabolism in the human hypothalamus: observations in Parkinson's disease and normal subjects

1994 • 80 citations

?Real time? measurement of endogenous dopamine release during short trains of pulses in slices of rat neostriatum and nucleus accumbens : role of autoinhibition

1991 • 77 citations

Fast cyclic voltammetry: Measuring transmitter release in ‘real time’

1990 • 72 citations

Analysis of Dose—Response Relationships

1976 • 71 citations

Presynaptic mediation by α2-, β1- and β2-adrenoceptors of endogenous noradrenaline and dopamine release from slices of rat hypothalamus

1983 • 70 citations

5-HT2 antagonists and minaprine block the 5-HT-induced inhibition of dopamine release from rat brain striatal slices

1988 • 67 citations

Transmitter release patterns of noradrenergic, dopaminergic and cholinergic axons in rabbit brain slices during short pulse trains, and the operation of presynaptic autoreceptors

1988 • 66 citations

Pharmacological characterization of presynaptic α₂‐autoreceptors in rat submaxillary gland and heart atrium

1992 • 65 citations

Presynaptic noradrenergic α-receptros and modulation of 3H-noradrenaline release from rat brain synaptosomes

1979 • 63 citations

Noradrengic mechanisms in Parkion's disease

1993 • 63 citations

Clonidine regularizes substantia nigra dopamine cell firing

1988 • 60 citations

Effect of prostaglandins D2, E2 and F2α on catecholamine release from slices of rat and rabbit brain

1981 • 59 citations

Are the prejunctional α2-adrenoceptors of the rat vas deferens and submandibular gland of the α2A-orα2D-subtype?

1992 • 53 citations

Lack of involvement of α2-adrenoceptors in the regulation of striatal dopaminergic transmission

1983 • 52 citations

Release-inhibiting ?2-adrenoceptors at serotonergic axons in rat and rabbit brain cortex: evidence for pharmacological identity with ?2-autoreceptors

1994 • 49 citations

?2 and ?-adrenoceptor agonists modulate [3H]dopamine release from rat nucleus accumbens slices: Implications for research into depression

1984 • 43 citations

Presynaptic regulation of electrically evoked dopamine overflow in nucleus accumbens: a pharmacological study using fast cyclic voltammetry in vitro

1991 • 41 citations

Alpha 2-adrenergic receptors of the alpha 2c subtype mediate inhibition of norepinephrine release in human kidney cortex.

1994 • 38 citations

Receptor reserve at the alpha-2 adrenergic receptor in the rat cerebral cortex.

1987 • 35 citations

Modulation of dopaminergic transmission by alpha-noradrenergic agonists and antagonists: Evidence for antidopaminergic properties of some alpha antagonists

1982 • 30 citations

Characterization of prejunctional alpha-2 adrenergic receptors involved in modulation of adrenergic transmitter release in the isolated perfused rat kidney.

1992 • 22 citations

Lack of interaction between ?2 and dopamine D2-receptors in mediating their inhibitory effects on [3H]dopamine release from rat nucleus accumbens slices

1993 • 21 citations

Characterization of sensory neurotransmission and its inhibition via ?2B-adrenoceptors and via non-?2-receptors in rabbit iris

1993 • 20 citations

Alpha-2 adrenoceptors modulate [3H]dopamine release from rabbit retina.

1984 • 17 citations

Presynaptic regulation of the electrically evoked release of endogenous dopamine from the isolated neurointermediate lobe or isolated neural lobe of the rat pituitary gland in vitro

1988 • 15 citations

Presynaptic alpha-2 adrenoceptor activation and coupling of the receptor-presynaptic effector system in the perfused rat heart: affinity and efficacy of phenethylamines and imidazoline derivatives.

1986 • 12 citations

Effect of chronic antidepressant treatment on noradrenergic modulation of [3H]dopamine release from rat nucleus accumbens and striatal slices

1987 • 9 citations

Estimation of agonist dissociation constants at central presynaptic alpha-2 autoreceptors in the absence of autoinhibition.

1991 • 7 citations