Coordinate viral induction of tumor necrosis factor alpha and interferon beta in human B cells and monocytes.

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.

1986 • 1,079 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Tumour necrosis factors α and β inhibit virus replication and synergize with interferons

1986 • 726 citations

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

1986 • 577 citations

Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor.

1988 • 561 citations

Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor

1986 • 528 citations

Production of High-Titered Interferon in Cultures of Human Diploid Cells

1972 • 471 citations

Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon.

1983 • 458 citations

Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.

1986 • 396 citations

Antiviral effects of recombinant tumour necrosis factor in vitro

1986 • 392 citations

Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.

1986 • 280 citations

Additive effects of interleukin 1 and tumour necrosis factor-alpha on the accumulation of the three granulocyte and macrophage colony-stimulating factor mRNAs in human endothelial cells.

1987 • 238 citations

Activation of the human beta-interferon gene requires an interferon-inducible factor.

1986 • 237 citations

Interferon-β gene regulation: Tandemly repeated sequences of a synthetic 6 bp oligomer function as a virus-inducible enhancer

1987 • 233 citations

2-Aminopurine Selectively Inhibits the Induction of β-Interferon, c- fos , and c- myc Gene Expression

1988 • 233 citations

B cell growth modulating and differentiating activity of recombinant human 26-kd protein (BSF-2, HuIFN-beta 2, HPGF).

1987 • 220 citations

Tumor Necrosis Factors: Gene Structure and Biological Activities

1986 • 215 citations

Differential expression of human interferon genes

1984 • 184 citations

The activation of protein kinase C by biologically active lipid moieties of lipopolysaccharide.

1984 • 180 citations

Tumor necrosis factor induction by Sendai virus.

1986 • 177 citations

Production of tumor necrosis factor/cachectin by human B cell lines and tonsillar B cells.

1988 • 173 citations

Defective interfering particles with covalently linked [±]RNA induce interferon

1977 • 169 citations

Functional equivalents of interferon-mediated signals needed for induction of an mRNA can be generated by double-stranded RNA and growth factors.

1987 • 141 citations

Interferon Induction by Viruses. XVI. 2-Aminopurine Blocks Selectively and Reversibly an Early Stage in Interferon Induction

1988 • 80 citations

Characteristics of Human Lymphoblastoid (Namalva) Interferon

1978 • 80 citations

Synergistic interactions of interleukin 1, interferon-beta, and tumor necrosis factor in terminally differentiating a mouse myeloid leukemic cell line (M1). Evidence that interferon-beta is an autocrine differentiating factor.

1988 • 79 citations

Activation of the Human β-Interferon Gene Requires an Interferon-Inducible Factor

1986 • 78 citations

Tumor necrosis factor and IFN induce a common set of proteins.

1988 • 43 citations

Sendai virus induces high levels of tumor necrosis factor mRNA in human peripheral blood leukocytes

1986 • 36 citations