Blockade of TGF-β by in vivo gene transfer of a soluble TGF-β type II receptor in the muscle inhibits corneal opacification, edema and angiogenesis

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

1992 • 2,969 citations

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

1993 • 1,941 citations

TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes

1997 • 1,404 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Macrophages and angiogenesis

1994 • 1,123 citations

An Assay for Transforming Growth Factor-β Using Cells Transfected with a Plasminogen Activator Inhibitor-1 Promoter-Luciferase Construct

1994 • 749 citations

Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.

1994 • 702 citations

Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects

1995 • 553 citations

Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only.

1994 • 548 citations

Adenoviruses as Gene-Delivery Vehicles

1996 • 480 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

A model of angiogenesis in the mouse cornea.

1996 • 411 citations

Basic Fibroblast Growth Factor Upregulates the Expression of Vascular Endothelial Growth Factor in Vascular Smooth Muscle Cells

1995 • 389 citations

Markers of mouse macrophage development detected by monoclonal antibodies

1994 • 345 citations

Three patterns of cytokine expression potentially involved in epithelial‐fibroblast interactions of human ocular surface

1995 • 338 citations

Blockade of type β transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat

1999 • 296 citations

Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways.

1991 • 219 citations

Growth factors in skin wound healing.

1995 • 210 citations

EGF, EGF receptor, basic FGF, TGF beta-1, and IL-1 alpha mRNA in human corneal epithelial cells and stromal fibroblasts.

1992 • 194 citations

Immunolocalization of TGF-beta 1, TGF-beta 2, and TGF-beta 3 in the anterior segment of the human eye.

1993 • 188 citations

Regional Suppression of Tumor Growth byIn VivoTransfer of a cDNA Encoding a Secreted Form of the Extracellular Domain of theflt-1Vascular Endothelial Growth Factor Receptor

1998 • 182 citations

Transforming growth factor-beta 1, -beta 2, and -beta 3 secreted by a human glioblastoma cell line. Identification of small and different forms of large latent complexes.

1992 • 181 citations

Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis.

1996 • 161 citations

Release of TGF-ß1 and VEGF in tears following photorefractive keratectomy

1997 • 120 citations

Vascular endothelial growth factor production is stimulated by gangliosides and TGF-β isoforms in human glioma cells in vitro

1996 • 117 citations

Experimental subretinal neovascularization is inhibited by adenovirus-mediated soluble VEGF/flt-1 receptor gene transfection: a role of VEGF and possible treatment for SRN in age-related macular degeneration

2000 • 103 citations

Identification of an inhibitor targeting macrophage production of monocyte chemoattractant protein-1 as TGF-beta 1.

1997 • 101 citations

TGF-beta2 in aqueous humor suppresses S-phase entry in cultured corneal endothelial cells.

1999 • 94 citations

Significance of angiogenesis in tumour progression and metastasis

1995 • 92 citations

TGF-beta induces expression of monocyte chemoattractant JE/monocyte chemoattractant protein 1 via transcriptional factor AP-1 induced by protein kinase in osteoblastic cells.

1995 • 85 citations

Adenovirus-mediated Transfer of a Truncated Transforming Growth Factor-β (TGF-β) Type II Receptor Completely and Specifically Abolishes Diverse Signaling by TGF-β in Vascular Wall Cells in Primary Culture

1996 • 80 citations

Cellular events associated with inflammatory angiogenesis in the mouse cornea.

1991 • 77 citations

Transforming growth factor-beta receptor expression in human cornea.

1997 • 75 citations

Corneal neovascularization induced by xenografts or chemical cautery. Inhibition by cyclosporin A.

1997 • 69 citations

Immunohistochemical localization of transforming growth factor-beta 1, -beta 2, and -beta 3 latency-associated peptide in human cornea.

1994 • 67 citations

Quantitative Analysis of Repeat Adenovirus-Mediated Gene Transfer Into Injured Canine Femoral Arteries

1995 • 60 citations

Eye-derived cytokines and the immunosuppressive intraocular microenvironment: a review

1992 • 59 citations

Adenovirus-Mediated Gene Transfer to the Ocular Surface Epithelium

1998 • 56 citations

Gene expression of monocyte chemoattractant protein-1 in giant cell tumors of bone osteoclastoma: Possible involvement in CD68+ macrophage-like cell migration

1998 • 54 citations

Ectopic expression of DNA encoding IFN-alpha 1 in the cornea protects mice from herpes simplex virus type 1-induced encephalitis.

1999 • 51 citations

Transforming growth factor-?1 expression in cultured corneal fibroblasts in response to injury

2000 • 48 citations

Expression of transforming growth factor-beta in wound healing of vitamin A-deficient rat corneas.

1989 • 43 citations

The macrophage cell surface glycoprotein F4/80 is a highly glycosylated proteoglycan

1996 • 42 citations

Ectopic Expression of DNA Encoding IFN-α1 in the Cornea Protects Mice from Herpes Simplex Virus Type 1-Induced Encephalitis

1999 • 40 citations

Inhibition of corneal inflammation by the topical use of Ras farnesyltransferase inhibitors: selective inhibition of macrophage localization.

1998 • 38 citations

Immunomodulation by mucosal gene transfer using TGF-beta DNA.

1998 • 37 citations

Retinal Functional Change Caused by Adenoviral Vector-Mediated Transfection of LacZ Gene

1998 • 35 citations