Antigen-induced biphasic diacylglycerol formation in RBL-2H3 cells: The late sustained phase due to phosphatidylcholine hydrolysis is dependent on protein kinase C

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

The regulation and cellular functions of phosphatidylcholine hydrolysis

1990 • 862 citations

RECEPTORS AND PHOSPHOINOSITIDE-GENERATED SECOND MESSENGERS

1985 • 722 citations

IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

1981 • 586 citations

Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils

1989 • 429 citations

Differential Down-regulation of Protein Kinase C Isozymes

1989 • 219 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

Regulation of phospholipid metabolism in differentiating cells from rat brain cerebral hemispheres in culture. Patterns of acetylcholine phosphocholine, and choline phosphoglycerides labeling from (methyl-14C)choline.

1976 • 164 citations

Phosphatidylethanol Biosynthesis in Ethanol-exposed NG108-15 Neuroblastoma X Glioma Hybrid Cells

1989 • 151 citations

Muscarinic Receptor Activation of Phosphatidylcholine Hydrolysis

1989 • 146 citations

Phorbol diesters stimulate the accumulation of phosphatidate, phosphatidylethanol, and diacylglycerol in three cell types. Evidence for the indirect formation of phosphatidylcholine-derived diacylglycerol by a phospholipase D pathway and direct formation of diacylglycerol by a phospholipase C pathway.

1990 • 113 citations

An indirect pathway of receptor-mediated 1,2-diacylglycerol formation in mast cells. I. IgE receptor-mediated activation of phospholipase D.

1990 • 109 citations

Elevated cytosolic Ca2+ activates phospholipase D in human platelets

1991 • 90 citations

The kinetics of phosphoinositide hydrolysis in rat basophilic leukemia (RBL-2H3) cells varies with the type of IgE receptor cross-linking agent used.

1987 • 79 citations

Mechanism of arachidonic acid liberation in platelet-activating factor-stimulated human polymorphonuclear neutrophils.

1989 • 66 citations

Stimulation of phosphatidylcholine breakdown and diacylglycerol production by growth factors in Swiss-3T3 cells

1989 • 56 citations

Phosphatidylcholine is a quantitatively more important source of increased 1,2-diacylglycerol than is phosphatidylinositol in mast cells.

1990 • 44 citations

Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells

1990 • 36 citations

Bradykinin-induced translocation of protein kinases C in neuroblastoma NCB-20 cell: Dependence on 1,2-diacylglycerol content and free calcium

1989 • 31 citations

Antigen-induced phospholipase D activation in rat mast cells is independent of protein kinase C

1991 • 24 citations

Polyphosphoinositide turnover in rat mast cells stimulated by antigen: Rapid and preferential breakdown of phosphatidylinositol 4-phosphate (DPI)

1984 • 23 citations

Differential down-regulation of protein kinase C selectively affects IgE-dependent exocytosis and inositol trisphosphate formation

1990 • 21 citations