Are L-tyrosine and L-dopa hormone-like bioregulators?

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Molecular Biology of the Cell

1990 • 951 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

1989 • 861 citations

A molecular basis for bidirectional communication between the immune and neuroendocrine systems.

1989 • 842 citations

Supramolecular Chemistry: Receptors, Catalysts, and Carriers

1985 • 778 citations

BIOCHEMISTRY OF MELANIN FORMATION

1950 • 623 citations

Positive autoregulation of the myogenic determination gene MyoD1

1989 • 492 citations

Mammalian tyrosinase—The critical regulatory control point in melanocyte pigmentation

1987 • 439 citations

The Identification of Contact Allergens by Human Assay III. The Maximization Test: A Procedure for Screening and Rating Contact Sensitizers

1989 • 406 citations

The coat colours of mice. A model for mammalian gene action and interaction.

1979 • 401 citations

Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein

1988 • 365 citations

Dermatology in General Medicine

1988 • 338 citations

Functional analysis of alternatively spliced tyrosinase gene transcripts.

1988 • 275 citations

Autocrine Stimulation of Intracellular PDGF Receptors in v- sis -Transformed Cells

1988 • 267 citations

Pigmentation; its genesis and biologic control

1972 • 262 citations

Cloning and expression of cDNA encoding mouse tyrosinase

1986 • 241 citations

Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA.

1989 • 186 citations

Multiple transcripts of the mouse tyrosinase gene are generated by alternative splicing.

1988 • 184 citations

REGULATORY PROTEINS IN YEAST

1987 • 173 citations

Regulation of macrophage functions by L-arginine.

1989 • 173 citations

The biosynthesis of mammalian melanin.

1982 • 168 citations

Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, l-tyrosine and l-dopa

1988 • 160 citations

Mechanism of induction of cytochrome P-450 by phenobarbital.

1981 • 159 citations

Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression

1988 • 156 citations

Substrate-induced synthesis of the hydroxylating enzyme system of liver microsomes.

1965 • 152 citations

3,4-Dihydroxy-l-phenylalanine as the Tyrosinase Cofactor

1967 • 134 citations

Induction of swimming in lamprey by L-DOPA and amino acids

1980 • 133 citations

Specific Identification of an Authentic Clone for Mammalian Tyrosinase

1989 • 106 citations

Catecholamine synthesis: Physiological coupling to precursor supply

1986 • 100 citations

Selective Induction of Two Different Molecular Species of Cytochrome P-450 by Phenobarbital and 3-Methylcholanthrene

1981 • 95 citations

Occurrence and function of amines in endocrine cells producing polypeptide hormones.

1973 • 93 citations

Serotonin and morphogenesis : I. Sites of serotonin uptake and -binding protein immunoreactivity in the midgestation mouse embryo

1988 • 89 citations

Tyrosinases of murine melanocytes with mutations at the albino locus.

1988 • 88 citations

L‐Tyrosine, L‐DOPA, and Tyrosinase as Positive Regulators of the Subcellular Apparatus of Melanogenesis in Bomirski Ab Amelanotic Melanoma Cells

1989 • 85 citations

Regulation of ribonucleotide reductase in mammalian cells by chemotherapeutic agents

1981 • 80 citations

The natural history of a family of transplantable melanomas in hamsters

1988 • 78 citations

Behavior, Hormones, and Hydra

1968 • 77 citations

Locally formed dopamine inhibits Na+-K+-ATPase activity in rat renal cortical tubule cells

1988 • 76 citations

Mammalian Metallothionein Is Functional in Yeast

1986 • 76 citations

Regulation of Melanogenesis in Melanocytes

1988 • 73 citations

Pigment Cell Biology: An Historical Review

1989 • 72 citations

Production of interleukin 1 activity by cultured human melanoma cells.

1989 • 71 citations

Pathogenetic problems in phenylketonuria

1957 • 67 citations

A ventrally localized inhibitor of melanization in Xenopus laevis skin

1988 • 66 citations

Sequence homology between Lac and Gal repressors and three sugar-binding periplasmic proteins

1983 • 65 citations

On the hyperglycaemic effect of DOPA and dopamine

1967 • 58 citations

Anticarcinogenic Action of Protease Inhibitors

1987 • 57 citations

GROWTH HORMONE (GH) RESPONSES TO ARGININE AND L‐DOPA ALONE AND AFTER GHRH PRETREATMENT

1988 • 54 citations

Control of Melanoblast Differentiation in Amphibia by α‐Melanocyte Stimulating Hormone, a Serum Melanization Factor, and a Melanization Inhibiting Factor

1989 • 51 citations

UVR induction of TGFα: a possible autocrine mechanism for the epidermal melanocytic response and for promotion of epidermal carcinogenesis

1988 • 49 citations

Tyrosine: Effects on catecholamine release

1988 • 49 citations

MSH inhibits growth in a line of amelanotic hamster melanoma cells and induces increases in cyclic AMP levels and tyrosinase activity without inducing melanogenesis

1989 • 47 citations

Levels of tyrosinase and its mRNA in coat‐color mutants of C57Bl/10J congenic mice: Effects of genic substitution at the agouti, brown, albino, dilute, and pink‐eyed dilution loci

1989 • 47 citations

L-Tyrosine stimulates induction of tyrosinase activity by MSH and reduces cooperative interactions between MSH receptors in hamster melanoma cells

1989 • 45 citations

On the Mechanism of Action and Evolution of Receptors Associated with Feeding and Digestion

1974 • 45 citations

pH-dependent interconversion of two forms of tyrosinase in human skin

1988 • 41 citations

Histochemical Studies on the Metabolism of L‐DOPA and Some Related Substances in the Exocrine Pancreas

1969 • 40 citations

Inhibition of Melanization in Human Melanoma Cells by a Serotonin Uptake Inhibitor

1987 • 39 citations

Autoregulation of the yeast copper metallothionein gene depends on metal binding.

1988 • 38 citations

Biochemical characterization of three hamster melanoma variants—II. Glycolysis and oxygen consumption

1984 • 36 citations

Phosphorylated isomers of L-dopa stimulate MSH binding capacity and responsiveness to MSH in cultured melanoma cells

1987 • 36 citations

The effect of carbidopa on plasma and muscle levels of <scp>L</scp>‐dopa, dopamine, and their metabolites following <scp>L</scp>‐dopa administration to rats

1988 • 36 citations

Dopaquinone addition products in cultured human melanoma cells

1987 • 33 citations

Does melanin do more than protect from light?

1987 • 30 citations

L-tyrosine induces synthesis of melanogenesis related proteins

1989 • 30 citations

Metabolic characterization of three hamster melanoma variants.

1985 • 29 citations

Glutathionedopa in malignant melanoma

1977 • 28 citations

Melanosomal Antigenic Expression on the Cell Surface and Intracellular Subunits Within Melanogenic Compartments of Pigment Cells: Analysis by Antimelanosome-Associated Monoclonal Antibody

1986 • 25 citations

Levodopa Administration and Multiple Primary Cutaneous Melanomas

1980 • 24 citations

L-DOPA INDUCED PLASMA GLUCAGON RELEASE

1974 • 24 citations

Enhancement Of Pheomelanogenesis By L-Dopa In The Mouse Melanocyte Cell Line, Tm10, In Vitro

1987 • 24 citations

The role of NADP-dependent dehydrogenases in hydroxylation of tyrosine in hamster melanoma.

1983 • 20 citations

MSH binding in bomirski amelanotic hamster melanoma cells is stimulated by L-tyrosine

1987 • 20 citations

Protein-bound dopa and 5-S-cysteinyldopa in non-melanogenic tissues

1983 • 19 citations

Receptor-level interrelationships of amino acids and the adequate amino acid type hormones in Tetrahymena: A receptor evolution model

1986 • 19 citations

Evidence for the Involvement of Central Opioidergic Systems in L-Tyrosine Methyl Ester-Induced Analgesia in the Rat

1988 • 16 citations

Development of Immune Complexes In the Skin

1989 • 16 citations

In vitro uptake of L-dopa and catecholamines into the epidermal Langerhans cell.

1978 • 15 citations

Formation of glutathionedopa in albino rats after DOPA injection

1981 • 15 citations

THE EFFECT OF A PHENYLALANINE‐TYROSINE LOW DIET ON THE GROWTH AND MORPHOLOGY OF TRANSPLANTABLE MALIGNANT MELANOMAS OF THE SYRIAN GOLDEN HAMSTER (MESOCRICETUS AURATUS)

1973 • 14 citations

SENSITIVITY OF MOUSE SKH:HR‐2 TO ULTRAVIOLET LIGHT: MOUSE PIGMENTATION MODEL

1986 • 13 citations

A possible role for melanin precursors in regulating both pigmentation and proliferation of melanocytes.

1988 • 13 citations

The effects of intravenous L-dopa on plasma renin activity, renal function, and blood pressure in man

1988 • 13 citations

L-Serine Potentiates the Mitogenic Effects of Growth Factors on Cultured Human Keratinocytes

1987 • 13 citations

Induction of the Synthesis of Melanin and Pteridine in Cells Isolated from the Axolotl Embryo

1984 • 13 citations

5-S-cysteinyldopa, dopa, and dopamine in the kidney and some other tissues

1980 • 12 citations

Phosphorylated Mixed Isomers of <scp>l</scp>‐Dopa Increase Melanin Content in Skins of Skh‐2 Pigmented Hairless Mice

1987 • 12 citations

Hormone evolution studies: Multiplication promoting and imprinting (“memory”) effects of various amino acids on Tetrahymena

1987 • 11 citations

Levodopa and dopamine analogs: dihydroxy and trihydroxybenzylamines as novel quinol antitumor agents in experimental leukemia in vivo.

1981 • 11 citations

Differentiation and melanin production in hyaline and pigmented strains of Microdochium bolleyi

1984 • 10 citations

Cardiovascular effects of L-tyrosine: influence of blockade of tyrosine metabolism

1989 • 10 citations

Intracellular distribution of dopa and 5-S-cysteinyldopa in pigment cells with minimal pigment formation

1979 • 10 citations

Tyrosine and the synthesis of melanin in embryonic cells fromAmbystoma mexicanum

1978 • 9 citations

Reducing Agents Structurally Related to Catechols as Inhibitors of DNA Synthesis in Mammalian Cells

1987 • 8 citations

Inhibition of Transformation by Levodopa-Carbidopa in Lymphocytes Derived From Patients With Melanoma

1987 • 8 citations

Presynaptic Binding of Amino Acids: Characterization of the Binding and Dissociation Properties of Taurine, Gaba, Glutamate, Tyrosine and Norleucine

1983 • 7 citations

Melanophore Differentiation in the Periodic Albino Mutant of Xenopus laevis

1987 • 7 citations

Effect of l- and d-tyrosine on in vitro transport and phosphorylation of thiamine in rats

1980 • 7 citations

Dissimilar effects of L and D amino acids on the growth of Tetrahymena

1987 • 7 citations

Pretreatment Effects on the Uptake/Retention Kinetics of L-Dopa in Harding-Passey Melanoma

1986 • 7 citations

Effects of L-dopa, GPA 1734 and other agents on basement membrane biosynthesis.

1978 • 7 citations

Pigmented Hyperplasia of Epidermis Following Feeding of l -Dopa to Elderly Rats

1977 • 6 citations

Photoaffinity labelling of a tyrosine chemoreceptor in Pseudomonas aeruginosa

1979 • 6 citations

Levodopa administration and multiple primary cutaneous melanomas

1980 • 6 citations

Melanogenesis of human melanoma cells cultured in a tyrosine depleted medium

1984 • 5 citations

Calcium-Dependent Release of Tyrosine in Brain Elicited by Stimulation of Neuropeptide Receptors

1987 • 5 citations

Untitled

1979 • 3 citations

[Phenotypic correction of the immune response by L-tyrosine in mice reacting oppositely to sheep erythrocytes].

1988 • 1 citations

[Phenotypic correction of the immune response by L-tyrosine in mice reacting oppositely to sheep erythrocytes].

1988 • 1 citations