Developmental and Regional Studies of the Metabolism of Inositol 1,4,5‐Trisphosphate in Rat Brain

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Histochemistry of Hepatic Phosphatases at a Physiologic pH: With Special Reference to the Demonstration of Bile Canaliculi

1957 • 1,831 citations

The inositol tris/tetrakisphosphate pathway—demonstration of Ins(l,4,5)P3 3-kinase activity in animal tissues

1986 • 702 citations

Characterization of inositol trisphosphate receptor binding in brain. Regulation by pH and calcium.

1987 • 551 citations

The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane

1982 • 541 citations

Competitive, reversible, and potent antagonism of inositol 1,4,5-trisphosphate-activated calcium release by heparin.

1988 • 427 citations

Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors.

1986 • 399 citations

Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.

1983 • 394 citations

Receptor Activation and Inositol Lipid Hydrolysis in Neural Tissues

1987 • 341 citations

Metabolism of the inositol phosphates produced upon receptor activation

1989 • 305 citations

Inositol trisphosphate receptor localization in brain: variable stoichiometry with protein kinase C

1987 • 249 citations

Protein determination by Lowry's method in the presence of sulfhydryl reagents

1972 • 244 citations

Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate.

1985 • 233 citations

A simple, sensitive, and specific radioreceptor assay for inositol 1,4,5-trisphosphate in biological tissues

1989 • 164 citations

The effect of external calcium and pH on inositol trisphosphate-mediated calcium release from cerebellum microsomal fractions

1989 • 139 citations

Separation of multiple isomers of inositol phosphates formed in GH3 cells

1987 • 138 citations

Characterization of D-myo-inositol 1,4,5-trisphosphate phosphatase in rat liver plasma membranes.

1984 • 131 citations

Inositol 1,4,5-trisphosphate receptor binding: autoradiographic localization in rat brain

1989 • 125 citations

Purification and characterization of two types of soluble inositol phosphate 5-phosphomonoesterases from rat brain.

1987 • 102 citations

Isolation and separation of inositol phosphates from hydrolysates of rat tissues

1965 • 95 citations

Inositol bis-, tris-, and tetrakis(phosphate)s: analysis in tissues by HPLC.

1986 • 93 citations

Catalytic properties of inositol trisphosphate kinase: activation by Ca ²⁺ and calmodulin

1987 • 84 citations

Calcium-calmodulin stimulates inositol 1,4,5-trisphosphate kinase activity from insulin-secreting RINm5F cells.

1987 • 83 citations

Enhanced Coupling of Neonatal Muscarinic Receptors in Rat Brain to Phosphoinositide Turnover

1987 • 79 citations

How do inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate regulate intracellular Ca2+?

1989 • 74 citations

Purification of D-myo-inositol 1,4,5-trisphosphate 3-kinase from rat brain.

1988 • 67 citations

Phospholipase C I and II brain isozymes: immunohistochemical localization in neuronal systems in rat brain.

1988 • 66 citations

Turkey erythrocytes possess a membrane-associated inositol 1,4,5-trisphosphate 3-kinase that is activated by Ca2+ in the presence of calmodulin

1987 • 62 citations

Characterization of D-myo-inositol 1,4,5-trisphosphate phosphatase in rat brain

1986 • 61 citations

Partial purification and some properties of rat brain inositol 1,4,5-trisphosphate 3-kinase

1988 • 54 citations

Purification and characterization of inositol 1,4,5-trisphosphate 3-kinase from pig aortic smooth muscle

1988 • 48 citations

5′-Nucleotidase in postnatal ontogeny of rat cerebellum: a marker for migrating nerve cells?

1988 • 48 citations

Characterization of inositol 1,4,5-trisphosphate-stimulated calcium release from rat cerebellar microsomal fractions. Comparison with [3H]inositol 1,4,5-trisphosphate binding.

1988 • 41 citations

Degradation of inositol 1,3,4,5-tetrakisphosphates by porcine brain cytosol yields inositol 1,3,4-trisphosphate and inositol 1,4,5-trisphosphate

1988 • 36 citations

Postnatal ontogeny of agonist and depolarization-induced phosphoinositide hydrolysis in rat cerebral cortex.

1987 • 31 citations

The dephosphorylation pathway of <scp>d</scp>-myo-inositol 1,3,4,5-tetrakisphosphate in rat brain

1987 • 30 citations

Calcium modulates the generation of inositol 1,3,4-trisphosphate in human platelets by the activation of inositol 1,4,5-trisphosphate 3-kinase

1988 • 21 citations