Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the v-abl oncogene.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

The embryonic cell lineage of the nematode Caenorhabditis elegans

1983 • 4,070 citations

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

1977 • 3,432 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

Determination of the base composition of deoxyribonucleic acid from its buoyant density in CsCl

1962 • 1,597 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

The lin-12 locus specifies cell fates in caenorhabditis elegans

1983 • 598 citations

The Caenorhabditis elegans male: Postembryonic development of nongonadal structures

1980 • 588 citations

THE DNA OF CAENORHABDITIS ELEGANS

1974 • 583 citations

Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

1982 • 540 citations

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity

1984 • 539 citations

Mutations that lead to reiterations in the cell lineages of C. elegans

1981 • 530 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

A bacteriophage lambda vector for cloning large DNA fragments made with several restriction enzymes

1980 • 379 citations

Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).

1981 • 363 citations

Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites

1984 • 345 citations

ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

1983 • 345 citations

Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product

1980 • 324 citations

Functional homology of mammalian and yeast RAS genes

1985 • 324 citations

Primary structure of the α-subunit of transducin and its relationship to ras proteins

1985 • 291 citations

Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies Between Transducin, ras , and Elongation Factors

1985 • 276 citations

Abnormal cell lineages in mutants of the nematode Caenorhabditis elegans

1981 • 270 citations

DNA sequences homologous to vertebrate oncogenes are conserved in Drosophila melanogaster.

1981 • 269 citations

Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activity.

1983 • 253 citations

Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability

1984 • 228 citations

The mouse c-abl locus: Molecular cloning and characterization

1984 • 223 citations

A systematic DNA sequencing strategy

1982 • 213 citations

Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence.

1985 • 202 citations

The Drosophila EGF receptor gene homolog: Conservation of both hormone binding and kinase domains

1985 • 202 citations

The drosophila ras oncogenes: Structure and nucleotide sequence

1984 • 175 citations

GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence.

1985 • 169 citations

Isolation of the proto-oncogene c-myb from D. melanogaster

1985 • 157 citations

THE GENETIC CONTROL OF CELL LINEAGE DURING NEMATODE DEVELOPMENT

1984 • 130 citations

Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence.

1983 • 124 citations

Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity

1984 • 119 citations

Nucleotide sequences of the drosophila src and abl homologs: conservation and variability in the src family oncogenes

1983 • 114 citations

Homology between phosphotyrosine acceptor site of human c-abl and viral oncogene products

1983 • 86 citations

Localization of tyrosine kinase-coding region in v-abl oncogene by the expression of v-abl-encoded proteins in bacteria.

1985 • 70 citations

Expression of the src and abl cellular oncogenes during development of Drosophila melanogaster.

1984 • 46 citations

Cellular RNA Homologous to the Abelson Murine Leukemia Virus Transforming Gene: Expression and Relationship to the Viral Sequence

1983 • 42 citations

Site-directed point mutation in the src gene oF rous sarcoma virus results in an inactive src gene product

1983 • 34 citations

Expression of the src and abl Cellular Oncogenes During Development of Drosophila melanogaster

1984 • 5 citations