Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target

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MDMX: a novel p53-binding protein with some functional properties of MDM2.

1996 • 624 citations

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1998 • 583 citations

The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity

1990 • 569 citations

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities

2000 • 515 citations

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

2001 • 505 citations

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities

2000 • 398 citations

DOUBLE MINUTES AND HOMOGENEOUSLY STAINING REGIONS: Gene Amplification in Mammalian Cells

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MDM2 interacts with MDMX through their RING finger domains

1999 • 319 citations

Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene.

1996 • 267 citations

Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification.

1999 • 246 citations

Pten signaling in gliomas

2002 • 189 citations

Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and nonrandom chromosomal gains and losses.

1994 • 180 citations

Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.

1996 • 175 citations

Isolation and Identification of the Human Homolog of a New p53-Binding Protein, Mdmx

1997 • 151 citations

A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer

1997 • 147 citations

Pten signaling in gliomas

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Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA.

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Oncogene amplification in human gliomas: a molecular cytogenetic analysis.

1994 • 84 citations

Comparative genomic hybridization in glioma

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Nonrandom Chromosomal Imbalances in Esophageal Squamous Cell Carcinoma Cell Lines: Possible Involvement of the ATF3 and CENPF Genes in the 1q32 Amplicon

2000 • 73 citations

Frequent In activation of CDKN2A and Rare Mutation of TP53 in PCNSL

1998 • 72 citations

A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome 1q32.1.

1994 • 71 citations

GAC1, a new member of the leucine-rich repeat superfamily on chromosome band 1q32.1, is amplified and overexpressed in malignant gliomas

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Structure and Organization of Amplified DNA on Double Minutes Containing the mdm2 Oncogene

1993 • 64 citations

Cenp-F gene amplification and overexpression in head and neck squamous cell carcinomas

2001 • 63 citations

Genetic aberrations in oligodendroglial tumours: an analysis using comparative genomic hybridization (CGH)

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A chromosomal region 7p11.2 transcript map: Its development and application to the study of EGFR amplicons in glioblastoma

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Isolation of the cDNA and Chromosomal Localization of the Gene ( TAX1 ) Encoding the Human Axonal Glycoprotein TAG-1

1993 • 30 citations

The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas.

2001 • 25 citations

Locations of the ets Subfamily Membersnet, elk1,andsap1(ELK3, ELK1, and ELK4) on Three Homologous Regions of the Mouse and Human Genomes

1995 • 23 citations

The Complexity of the 7p12 Amplicon in Human Astrocytic Gliomas: Detailed Mapping of 246 Tumors

2000 • 22 citations