Leukemia inhibitory factor and interleukin‐11 promote maturation of murine and human megakaryocytes in vitro

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1989 • 3,477 citations

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.

1990 • 649 citations

Human interleukin 6 is a direct promoter of maturation of megakaryocytes in vitro.

1989 • 430 citations

Interleukin-6 is a potent thrombopoietic factor in vivo in mice

1989 • 422 citations

Purification of a factor inducing differentiation of mouse myeloid leukemic M1 cells from conditioned medium of mouse fibroblast L929 cells.

1984 • 318 citations

Regulation of megakaryocytopoiesis

1989 • 305 citations

Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S

1983 • 285 citations

In vivo effects of recombinant human interleukin-6 in primates: stimulated production of platelets

1990 • 280 citations

Molecular cloning and expression of hybridoma growth factor in Escherichia coli.

1987 • 238 citations

Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture.

1991 • 234 citations

Effects of injected leukemia inhibitory factor on hematopoietic and other tissues in mice

1990 • 226 citations

Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin‐11

1991 • 156 citations

Stimulation of thrombopoiesis in mice by human recombinant interleukin 6.

1990 • 151 citations

Effects of recombinant interleukin 11 on human megakaryocyte progenitor cells.

1991 • 151 citations

Effect of interleukin 6 on in vitro human megakaryocytopoiesis: its interaction with other cytokines.

1989 • 140 citations

The leukemia inhibitory factor (LIF)

1991 • 127 citations

Interleukin-6 and its receptor are expressed by human megakaryocytes: in vitro effects on proliferation and endoreplication

1991 • 123 citations

Synergistic interactions between interleukin-11 and interleukin-4 in support of proliferation of primitive hematopoietic progenitors of mice

1991 • 118 citations

Leukemia inhibitory factor can potentiate murine megakaryocyte production in vitro

1991 • 117 citations

Effects of human interleukin-6 on megakaryocyte development and thrombocytopoiesis in primates

1991 • 109 citations

Recombinant human interleukin 6 is a potent inducer of the acute phase response and elevates the blood platelets in nonhuman primates.

1991 • 92 citations

Interleukin 6 is a differentiation factor for human megakaryocytes in vitro

1990 • 73 citations

Quantitation of megakaryocytopoiesis in liquid culture by enzymatic determination of acetylcholinesterase

1985 • 46 citations

Effect of fibrinogen concentration on the velocity of platelet aggregation

1991 • 40 citations

Interleukin 3 promotes maturation of murine megakaryocytes in vitro.

1986 • 32 citations

Megakaryocytic maturation in murine long-term bone marrow culture: role of interleukin-6

1991 • 28 citations

Immunomagnetic bead isolation of megakaryocytes from guinea‐pig bone marrow: effect of recombinant interleukin‐6 on size, ploidy and cytoplasmic fragmentation

1991 • 25 citations

Multiple levels of regulation of megakaryocytopoiesis.

1989 • 24 citations

Two new extracellular serine proteases from Streptomyces fradiae

1991 • 23 citations

Megakaryocytic maturation in murine long-term bone marrow culture: role of interleukin-6

1991 • 18 citations

Interleukin 6 and tumor necrosis factor fully activate liver-specific gene expression of the alpha chain of C4b-binding protein.

1991 • 4 citations