Covalent modification of actin by 4‐hydroxy‐trans‐2‐nonenal (HNE): LC‐ESI‐MS/MS evidence for Cys374 Michael adduction

The Regulation of Rabbit Skeletal Muscle Contraction

1971 • 4,491 citations

NAMD2: Greater Scalability for Parallel Molecular Dynamics

1999 • 2,396 citations

Free radical-mediated oxidation of free amino acids and amino acid residues in proteins

2003 • 1,787 citations

Contributions of mass spectrometry to peptide and protein structure

1988 • 992 citations

The Crystal Structure of Uncomplexed Actin in the ADP State

2001 • 522 citations

Protein oxidation in the brain in Alzheimer's disease

2001 • 495 citations

Identification of a factor in conventional muscle actin preparations which inhibits actin filament self-association

1980 • 473 citations

Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomics

2004 • 439 citations

VEGA: a versatile program to convert, handle and visualize molecular structure on Windows-based PCs

2002 • 429 citations

The actin cytoskeleton response to oxidants: from small heat shock protein phosphorylation to changes in the redox state of actin itself

2001 • 387 citations

Detailed peptide characterization using PEPTIDEMASS – a World‐Wide‐Web‐accessible tool

1997 • 341 citations

Crystal Structure of Monomeric Actin in the ATP State

2003 • 228 citations

Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease

2003 • 224 citations

Reversible S-glutathionylation of Cys374 regulates actin filament formation by inducing structural changes in the actin molecule

2002 • 195 citations

Mass spectrometry for detection of 4‐hydroxy‐trans‐2‐nonenal (HNE) adducts with peptides and proteins

2004 • 174 citations

Cation−π versus Anion−π Interactions: Energetic, Charge Transfer, and Aromatic Aspects

2004 • 172 citations

Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin

2003 • 151 citations

Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts

2004 • 149 citations

Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart

1999 • 143 citations

Covalent adduction of nucleophilic amino acids by 4-hydroxynonenal and 4-oxononenal

2003 • 140 citations

Protein Carbonyl Formation in the Diaphragm

2004 • 109 citations

Hydroxynonenal inactivates cathepsin B by forming Michael adducts with active site residues

2002 • 105 citations

Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor alpha in a human colonic cell line

2000 • 99 citations

Structural connectivity in actin: effect of C-terminal modifications on the properties of actin

1994 • 96 citations

S-NO-actin: S-nitrosylation kinetics and the effect on isolated vascular smooth muscle.

2000 • 89 citations

Determination of the Sites of 4-Hydroxy-2-nonenal Adduction to Protein by Electrospray Tandem Mass Spectrometry

1996 • 85 citations

Study of protein modification by 4-hydroxy-2-nonenal and other short chain aldehydes analyzed by electrospray ionization tandem mass spectrometry

2003 • 84 citations

Actin is oxidized during myocardial ischemia

2001 • 76 citations

Detoxification of cytotoxic α,β‐unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle

2002 • 73 citations

OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability

2001 • 65 citations

Thetert-Butyl Hydroperoxide-Induced Oxidation of Actin Cys-374 Is Coupled with Structural Changes in Distant Regions of the Protein

1999 • 63 citations

Chemical modification of actin. Acceleration of polymerization and reduction of network formation by reaction with N-ethylmaleimide, (iodoacetamido)tetramethylrhodamine, or 7-chloro-4-nitro-2,1,3-benzoxadiazole

1982 • 32 citations

Mass spectral determination of skeletal/cardiac actin isoform ratios in cardiac muscle

2003 • 26 citations

Improved Synthesis of Various Isotope Labeled 4-Hydroxyalkenals and Peroxidation Intermediates

1995 • 24 citations

Inhibition of Cardiac Myocyte Contraction by 4-Hydroxy-<I>Trans<I>-2-Nonenal

2004 • 20 citations

Relocation of Cys374 of Actin Induced by Labeling with Fluorescent Dyes

2001 • 7 citations