Phenotypic expression of histocompatibility antigens in human primary tumours and metastases

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

1986 • 2,102 citations

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

Recombinant interferon-gamma increases HLA-DR synthesis and expression.

1983 • 577 citations

The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases

1986 • 539 citations

Major histocompatibility antigens: The human (HLA-A,-B,-C) and murine (H-2K, H-2D) class I molecules

1981 • 511 citations

THE DETAILED DISTRIBUTION OF HLA-A, B, C ANTIGENS IN NORMAL HUMAN ORGANS

1984 • 410 citations

Detection of a novel human class II HLA antigen

1983 • 387 citations

Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

1981 • 374 citations

Rejection of transplantable AKR leukaemia cells following MHC DNA-mediated cell transformation

1984 • 359 citations

Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer.

1985 • 358 citations

Tumorigenicity of cells transformed by adenovirus type 12 by evasion of T-cell immunity

1983 • 353 citations

HLA‐DR Antigens: Structure, Separation of Subpopulations, Gene Cloning and Function

1982 • 258 citations

Phenotypic dynamics of tumor progression in human malignant melanoma

1985 • 172 citations

SB-restricted presentation of influenza and herpes simplex virus antigens to human T-Iymphocyte clones

1983 • 167 citations

Histocompatibility Antigens on Murine Tumors

1985 • 164 citations

Differential expression of H–2 gene products in tumour cells is associated with their metastatogenic properties

1980 • 146 citations

Isolation of high-molecular-weight DNA from insects

1990 • 139 citations

HLA class I gene expression on human primary tumours and autologous metastases: demonstration of selective losses of HLA antigens on colorectal, gastric and laryngeal carcinomas

1989 • 127 citations

Tumour immunology: MHC antigens and malignancy

1986 • 119 citations

Recombinant interferon‐γ can induce the expression of HLA‐DR and ‐DC on DR‐negative melanoma cells and enhance the expression of HLA‐ABC and tumor‐associated antigens

1985 • 115 citations

Class II histocompatibility antigen expression in human melanocytes transformed by Harvey murine sarcoma virus (Ha-MSV) and Kirsten MSV retroviruses.

1986 • 81 citations

EXPERIMENTAL STRATEGIES AND INTERPRETATIONS IN THE ANALYSIS OF CHANGES IN MHC GENE EXPRESSION DURING TUMOUR PROGRESSION

1986 • 75 citations

Biological effects of γ‐interferon on human tumor cells: Quantity and affinity of cell membrane receptors for γ‐IFN in relation to growth inhibition and induction of HLA‐DR expression

1985 • 71 citations

Class I and II HLA antigen distribution in normal mucosa, adenoma and colon carcinoma: relation with malignancy and invasiveness.

1987 • 57 citations

Analysis of Major Histocompatibility Antigens and the Mononuclear Cell Infiltrate in Halo Nevi

1985 • 49 citations

HETEROGENEITY OF THE EXPRESSION OF CLASS I AND II HLA ANTIGENS IN HUMAN BREAST CARCINOMA

1986 • 47 citations

DIFFERENTIAL EXPRESSION OF HLA CLASS I AND II ANTIGENS IN PRIMARY AND METASTATIC MELANOMAS

1986 • 43 citations

Expression of HLA-A, -B, and -C and beta 2-microglobulin antigens in human choriocarcinoma cell lines.

1980 • 41 citations

Influence of class I H-2 gene expression on local tumor growth. Description of a model obtained from clones derived from a solid BALB/c tumor.

1986 • 30 citations

Characterization of Monoclonal Antibodies Directed Against HLA Class II Molecules

1986 • 21 citations

Resistance of metastatic tumor variants to tumor-specific cytotoxic T-lymphocytes not due to defects in expression of restricting major histocompatibility complex molecules in murine cells.

1984 • 19 citations

Analysis of a defect in the H-2 genes of SV40 transformed C3H fibroblasts that do not express H-2Kk.

1983 • 19 citations

EXPRESSION AND SUSCEPTIBILITY TO MODULATION BY INTERFERONS OF HLA CLASS I AND II ANTIGENS ON MELANOMA CELLS. IMMUNOHISTOCHEMICAL ANALYSIS AND CLINICAL RELEVANCE

1986 • 17 citations

The Biological Implications of the Abnormal Expression of Histocompatibility Antigens on Murine and Human Tumors

1987 • 13 citations