HLA class I gene expression on human primary tumours and autologous metastases: demonstration of selective losses of HLA antigens on colorectal, gastric and laryngeal carcinomas

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Separation of leukocytes from blood and bone marrow

1968 • 2,787 citations

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

1986 • 2,102 citations

Microdroplet Assay of Human Serum Cytotoxins

1964 • 2,088 citations

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

Major histocompatibility antigens: The human (HLA-A,-B,-C) and murine (H-2K, H-2D) class I molecules

1981 • 511 citations

The natural history of the major histocompatibility complex

1987 • 468 citations

THE DETAILED DISTRIBUTION OF HLA-A, B, C ANTIGENS IN NORMAL HUMAN ORGANS

1984 • 410 citations

Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

1981 • 374 citations

Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer.

1985 • 358 citations

Striking paucity of HLA-A, B, C and beta 2-microglobulin on human neuroblastoma cell lines.

1983 • 257 citations

The Major Histocompatibility Complex in Man

1981 • 229 citations

Heterogeneity in surface antigen and glycoprotein expression of cell lines derived from different melanoma metastases of the same patient. Implications for the study of tumor antigens.

1981 • 213 citations

Further evidence for derepression of H–2 and Ia-like specificities of foreign haplotypes in mouse tumour cell lines

1976 • 138 citations

Loss of HLA‐A,B,C and de novo expression of HLA‐D in colorectal cancer

1986 • 136 citations

Membrane Molecules Determined by the H-2 Associated Immune Response Region: Isolation and Some Properties

1974 • 134 citations

MHC imbalance and metastatic spread in Lewis lung carcinoma clones

1983 • 131 citations

Heterogeneity in the expression of HLA and tumor-associated antigens by surgically removed and cultured breast carcinoma cells.

1983 • 125 citations

H–2-like specificities of foreign haplotypes appearing on a mouse sarcoma after vaccinia virus infection

1976 • 123 citations

Variation in MHC Antigenic Profiles of Tumor Cells and its Biological Effects

1981 • 120 citations

Tumour immunology: MHC antigens and malignancy

1986 • 119 citations

Defective expression of MHC class I antigens is frequent in B‐cell lymphomas of high‐grade malignancy

1987 • 88 citations

EXPERIMENTAL STRATEGIES AND INTERPRETATIONS IN THE ANALYSIS OF CHANGES IN MHC GENE EXPRESSION DURING TUMOUR PROGRESSION

1986 • 75 citations

Independent regulation of H-2K and H-2D gene expression in murine teratocarcinoma somatic cell hybrids.

1980 • 67 citations

Class I and II HLA antigen distribution in normal mucosa, adenoma and colon carcinoma: relation with malignancy and invasiveness.

1987 • 57 citations

Stimulation of HLA-A,B,C by IFN-alpha. The derivation of Molt 4 variants and the differential expression of HLA-A,B,C subsets.

1985 • 56 citations

The biological consequences of altered MHC expression on tumours

1987 • 55 citations

HETEROGENEITY OF THE EXPRESSION OF CLASS I AND II HLA ANTIGENS IN HUMAN BREAST CARCINOMA

1986 • 47 citations

DIFFERENTIAL EXPRESSION OF HLA CLASS I AND II ANTIGENS IN PRIMARY AND METASTATIC MELANOMAS

1986 • 43 citations

Lack of class I H-2 antigens in cells transformed by radiation leukemia virus is associated with methylation and rearrangement of H-2 DNA.

1986 • 40 citations

REPRESSION OF CLASS I H‐2K,H‐2D ANTIGENS ON GR9 METHYLCHOLANTHRENE‐INDUCED TUMOUR CELL CLONES IS RELATED TO THE LEVEL OF DNA METHYLATION

1986 • 27 citations

ABSENCE OF FOUR H‐2^d ANTIGENIC SPECIFICITIES IN AN H‐2^d SARCOMA

1979 • 26 citations

Ia antigen on peripheral blood mononuclear leukocytes in man. I. Expression, biosynthesis, and function of HLA-DR antigen non-T cells.

1980 • 24 citations

Analysis of a defect in the H-2 genes of SV40 transformed C3H fibroblasts that do not express H-2Kk.

1983 • 19 citations

Expression of extra class I major histocompatibility antigens on T-cell acute lymphoblastic leukemia (ALL) lymphoblasts

1985 • 12 citations

A NOVEL MHC CLASS I MOLECULE AS A TUMOUR‐SPECIFIC ANTIGEN

1986 • 10 citations

Alterations of class I HLA genes in human colon cancers

1988 • 9 citations

LOSS OF POLYMORPHIC RESTRICTION FRAGMENTS OF CLASS I AND CLASS II MHC GENES IN A MALIGNANT MELANOMA

1986 • 9 citations

Clonal analysis of H-2 antigen expression by variants of a chemically induced murine tumor.

1981 • 6 citations

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