Early virologic response to treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C

Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection

2002 • 6,505 citations

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

2001 • 6,133 citations

Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C

1998 • 3,550 citations

Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis

1981 • 3,549 citations

Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection

2000 • 3,295 citations

Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus

1998 • 2,374 citations

Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy

1998 • 2,112 citations

Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa

1989 • 1,658 citations

Adherence to combination therapy enhances sustained response in genotype-1–infected patients with chronic hepatitis C

2002 • 998 citations

Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay

1993 • 703 citations

Natural history of chronic hepatitis B virus infection in taiwan: Studies of hepatitis B virus DNA in serum

1985 • 418 citations

Dose-dependent acute clearance of hepatitis C genotype 1 virus with interferon alfa

1997 • 337 citations

Impact of Interferon Alfa-2b and Ribavirin on Progression of Liver Fibrosis in Patients With Chronic Hepatitis C

2000 • 294 citations

Viral kinetics in patients with chronic hepatitis C treated with standard or peginterferon α2a

2001 • 276 citations

Differences in Viral Dynamics between Genotypes 1 and 2 of Hepatitis C Virus

2000 • 230 citations

Effect of interferon alfa on the dynamics of hepatitis C virus turnoverin vivo

1996 • 230 citations

Effectiveness of interferon alfa on incidence of hepatocellular carcinoma and decompensation in cirrhosis type C

1997 • 202 citations

Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: definition of optimal conditions for specimen collection and clinical application in interferon-treated patients.

1994 • 193 citations

Monitoring of viral levels during therapy of hepatitis C

2002 • 175 citations

Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: Definition of optimal conditions for specimen collection and clinical application in interferon-treated patients

1994 • 150 citations

Peginterferon alfa-2A (40 KD) (PEGASYS) in combination with ribavirin (RBV): efficacy and safety results from a phase III, randomized, double-blind, multicentre study examining effect of duration of treatment and RBV dose

2002 • 143 citations

Liver derived pro-inflammatory cytokines may be important in producing intracranial hypertension in acute liver failure

2002 • 109 citations

First phase viral kinetic parameters as predictors of treatment response and their influence on the second phase viral decline

2002 • 80 citations

Estimation of early hepatitis C viral clearance in patients receiving daily interferon and ribavirin therapy using a mathematical model

2001 • 79 citations

Correlation of serum HCV RNA and alanine aminotransferase levels in chronic hepatitis C patients during treatment with ribavirin

1994 • 51 citations

Prospective Multicenter Clinical Evaluation of AMPLICOR and COBAS AMPLICOR Hepatitis C Virus Tests

2001 • 49 citations

Treatment of Chronic Hepatitis C in Patients Who Failed Interferon Monotherapy: Effects of Higher Doses of Interferon and Ribavirin Combination Therapy

2000 • 44 citations

Treatment of chronic hepatitis C in patients who failed interferon monotherapy: effects of higher doses of interferon and ribavirin combination therapy

2000 • 36 citations

Decline of hepatitis C virus load in serum during the first 24 h after administration of interferon-beta as a predictor of the efficacy of therapy

2001 • 28 citations

A comparison of reverse transcription–polymerase chain reaction and branched‐chain DNA assays for hepatitis C virus RNA in patients receiving interferon treatment

1999 • 16 citations

HALT-C trial

2002 • 8 citations