Low-Dose-Rate Radiation Attenuates the Response of the Tumor Suppressor TP53

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest

1994 • 1,475 citations

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.

1995 • 865 citations

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

1994 • 620 citations

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1995 • 546 citations

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1996 • 544 citations

p53 in growth control and neoplasia

1996 • 488 citations

Regulation of the Sequence-specific DNA Binding Function of p53 by Protein Kinase C and Protein Phosphatases

1995 • 199 citations

Aspects of the adaptive response to very low doses of radiation and other agents

1996 • 170 citations

Fission-spectrum neutrons at reduced dose rates enhance neoplastic transformation

1982 • 159 citations

p53-dependent Induction of WAF1 by Heat Treatment in Human Glioblastoma Cells

1996 • 94 citations

Thyroid Nodularity and Chromosome Aberrations Among Women in Areas of High Background Radiation in China

1990 • 88 citations

Cancer Mortality Survey in a Spa Area (Misasa, Japan) with a High Radon Background

1992 • 84 citations

p53-Dependent Signal Transduction Induced by Stress.

1997 • 70 citations

Contribution of Protein Kinase C to p53-dependent WAF1 Induction Pathway after Heat Treatment in Human Glioblastoma Cell Lines

1998 • 37 citations

Radiation paradigm and its shift.

1994 • 12 citations

Radioadaptive response: An implication for the biological consequences of low dose-rate exposure to radiations

1996 • 11 citations