Immune surveillance of mouse brain perivascular spaces by blood‐borne macrophages

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

Microglia-specific localisation of a novel calcium binding protein, Iba1

1998 • 1,337 citations

T‐lymphocyte entry into the central nervous system

1991 • 1,168 citations

Turnover of resident microglia in the normal adult mouse brain

1992 • 679 citations

Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new view

1992 • 653 citations

Bone Marrow-derived Elements in the Central Nervous System: An Immunohistochemical and Ultrastructural Survey of Rat Chimeras

1992 • 395 citations

Unique monocyte subset in patients with AIDS dementia

1997 • 371 citations

Bone marrow derived elements and resident microglia in brain inflammation

1993 • 352 citations

Kinetics of Central Nervous System Microglial and Macrophage Engraftment: Analysis Using a Transgenic Bone Marrow Transplantation Model

1997 • 336 citations

Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations

1999 • 313 citations

Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury

1989 • 289 citations

Identity of ED2‐positive perivascular cells in rat brain

1989 • 281 citations

Immune Surveillance in the Injured Nervous System: T-Lymphocytes Invade the Axotomized Mouse Facial Motor Nucleus and Aggregate around Sites of Neuronal Degeneration

1998 • 276 citations

Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

1997 • 230 citations

Anatomical relationships of the pia mater to cerebral blood vessels in man

1986 • 222 citations

Mast Cells Migrate from Blood to Brain

2000 • 214 citations

The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis

1995 • 213 citations

Distribution of extracellular tracers in perivascular spaces of the rat brain

1991 • 208 citations

Directional and compartmentalised drainage of interstitial fluid and cerebrospinal fluid from the rat brain

1992 • 195 citations

Male Donor-derived Cells in the Brains of Female Sex-mismatched Bone Marrow Transplant Recipients

1993 • 184 citations

Perivascular cells act as scavengers in the cerebral perivascular spaces and remain distinct from pericytes, microglia and macrophages

1993 • 174 citations

Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation

1994 • 166 citations

Heterogeneity of microglial and perivascular cell populations: Insights gained from the facial nucleus paradigm

1993 • 162 citations

Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: A light, confocal, and electron microscopical study using a phagocytosis-dependent labeling technique

1997 • 153 citations

Ultrastructural Location of Major Histocompatibility Complex (MHC) Class II Positive Perivascular Cells in Histologically Normal Human Brain

1992 • 148 citations

Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation1This work was supported by National Institute of Health Grant (RO1 NS33070-03) and The Brain Tumor Society.1

1999 • 135 citations

Turnover of Rat Brain Perivascular Cells

2001 • 128 citations

Determination of the origin and nature of brain macrophages and microglial cells in mouse central nervous system, using non‐radioactive in situ hybridization and immunoperoxidase techniques

1992 • 122 citations

Immunology of the Nervous System

1998 • 121 citations

Axonal Damage Induced by Invading T Cells in Organotypic Central Nervous System Tissue in vitro: Involvement of Microglial Cells

2000 • 89 citations

Ultrastructural studies of perivascular cuffing cells in multiple sclerosis brain.

1975 • 85 citations

Old dyes for new scopes: the phagocytosis-dependent long-term fluorescence labelling of microglial cells in vivo

1994 • 81 citations

Migration of Exogenous Immature Hematopoietic Cells into Adult Mouse Brain Parenchyma under GFP-Expressing Bone Marrow Chimera

1999 • 75 citations

Presence of B7–2 (CD86) and lack of B7–1 (CD(80) on myelin phagocytosing MHC-II-positive rat microglia is associated with nondestructive immunity in vivo

2001 • 65 citations

Reactive astrocytes upregulate fas (CD95) and fas ligand (CD95L) expression but do not undergo programmed cell death during the course of anterograde degeneration

2000 • 58 citations

Involvement of Non‐Neuronal Cells in Entorhinal‐Hippocampal Reorganization Following Lesions

2000 • 57 citations

An attempt to differentiate further between microglia and fluorescent granular perithelial (FGP) cells by their capacity to incorporate exogenous protein

1985 • 46 citations

Long-lasting perivascular accumulation of major histocompatibility complex class II-positive lipophages in the spinal cord of stroke patients: possible relevance for the immune privilege of the brain

1997 • 42 citations

ED2-positive perivascular cells act as neuronophages during delayed neuronal loss in the facial nucleus of the rat

1996 • 39 citations

Identification of phagocytic glial cells after lesion-induced anterograde degeneration using double-fluorescence labeling: combination of axonal tracing and lectin or immunostaining

1997 • 35 citations

Introduction

1998 • 25 citations

Presence of B‐7.2 (CD86) and lack of B7‐1 (CD80) on myelin‐phagocytosing MHC‐II positive rat microglia are associated with nondestructive immunity in vivo

2001 • 10 citations

ED2‐positive perivascular cells act as neuronophages during delayed neuronal loss in the facial nucleus of the rat

1996 • 4 citations