Nerve growth factor (NGF) expression in rat microglia is induced by adenosine A2a-receptors

Microglia: a sensor for pathological events in the CNS

1996 • 4,309 citations

Nomenclature and classification of purinoceptors.

1994 • 1,569 citations

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1995 • 1,290 citations

The origin and nature of ramified and amoeboid microglia: A historical review and current concepts

1993 • 682 citations

Neuroprotective role of adenosine in cerebral ischaemia

1992 • 450 citations

Brain macrophages: evaluation of microglia and their functions

1992 • 443 citations

An Enzyme‐Linked Immunoassay for Nerve Growth Factor (NGF): A Tool for Studying Regulatory Mechanisms Involved in NGF Production in Brain and in Peripheral Tissues

1987 • 377 citations

Bone marrow derived elements and resident microglia in brain inflammation

1993 • 352 citations

Expression of nerve growth factor and nerve growth factor receptor tyrosine kinase Trk in activated CD4-positive T-cell clones.

1993 • 315 citations

Adenosine and Brain Ischemia

1995 • 298 citations

Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis

1995 • 265 citations

Current View on the Mononuclear Phagocyte System

1982 • 248 citations

Cyclooxygenase-2 expression in rat microglia is induced by adenosine A2a-receptors

1996 • 222 citations

Lipopolysaccharide-free conditions in primary astrocyte cultures allow growth and isolation of microglial cells

1989 • 217 citations

Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain

1990 • 194 citations

Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease

1990 • 174 citations

Both adenosine A1- and A2-receptors are required to stimulate microglial proliferation.

1996 • 140 citations

Adenosine A_2b Receptors Mediate an Increase in Interleukin (IL)‐6 mRNA and IL‐6 Protein Synthesis in Human Astroglioma Cells

1996 • 115 citations

Adenosine and its nucleotides stimulate proliferation of chick astrocytes and human astrocytoma cells

1992 • 114 citations

Brain macrophages: neurotoxic or neurotrophic effector cells?

1994 • 113 citations

Stimulation of reactive astrogliosis in vivo by extracellular adenosine diphosphate or an adenosine A₂ receptor agonist

1994 • 113 citations

Cellular immune response in multiple sclerosis plaques.

1990 • 112 citations

Comparison of prostanoid forming capacity of neuronal and astroglial cells in primary cultures

1985 • 109 citations

BOTH ADENOSINE A1- AND A2-RECEPTORS ARE REQUIRED TO STIMULATE MICROGLIAL PROLIFERATION**This is one of eight original papers on the subject “microglia”. Dr Peter Gebicke-Haerter (Dept. Psychiatry, University of Freiburg, Germany) acted as organiser and executive editor in the refereeing of these articles.

1996 • 109 citations

Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex

1996 • 102 citations

Further thoughts on directional cell movement during morphogenesis

1985 • 79 citations

Indications for P2-purinoceptor subtypes in guinea pig smooth muscle

1988 • 54 citations

Adenosine A2B receptor signalling is altered by stimulation of bradykinin or interleukin receptors in astroglioma cells

1994 • 29 citations