Regional Variations of Insulin-Like Growth Factor I (IGF-I), IGF-II, and Receptor Type 1 in Benign Prostatic Hyperplasia Tissue and Their Correlation with Intraprostatic Androgens¹

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*

1995 • 4,419 citations

Insulin-Like Growth Factors I and II. Peptide, Messenger Ribonucleic Acid and Gene Structures, Serum, and Tissue Concentrations*

1989 • 1,796 citations

The Endocrinology and Developmental Biology of the Prostate*

1987 • 1,047 citations

Origin and evolution of benign prostatic enlargement.

1978 • 530 citations

Insulin-Like Growth Factors (IGFs), IGF Receptors, and IGF-Binding Proteins in Primary Cultures of Prostate Epithelial Cells*

1991 • 361 citations

Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate

1994 • 323 citations

Regulation of prostatic growth and function by peptide growth factors

1996 • 313 citations

Light Microscopic Stereological Analysis of the Normal Human Prostate and of Benign Prostatic Hyperplasia

1979 • 306 citations

The Prostate and Prostatic Urethra: A Morphologic Synthesis

1972 • 282 citations

Structure, Evolution, Expression and Regulation of Insulin-Like Growth Factors I and II

1991 • 247 citations

Role of peptide growth factors in the prostate: A review

1993 • 165 citations

Protein and messenger ribonucleic acid (mRNA) for the type 1 insulin-like growth factor (IGF) receptor is decreased and IGF-II mRNA is increased in human prostate carcinoma compared to benign prostate epithelium.

1996 • 162 citations

Insulin-like growth factor-II overexpression in MCF-7 cells induces phenotypic changes associated with malignant progression.

1992 • 120 citations

Androgen induction of steroid 5 alpha-reductase may be mediated via insulin-like growth factor-I.

1993 • 119 citations

Effects of long-term treatment withSerenoa repens (Permixon®) on the concentrations and regional distribution of androgens and epidermal growth factor in benign prostatic hyperplasia

1998 • 111 citations

Insulin-like growth factor axis abnormalities in prostatic stromal cells from patients with benign prostatic hyperplasia.

1994 • 103 citations

Expression and Regulation of Steroid 5α-Reductase 2 in Prostate Disease

1994 • 91 citations

Hormonal Signaling in Prostatic Hyperplasia and Neoplasia*

1999 • 88 citations

The influence of finasteride on the volume of the peripheral and periurethral zones of the prostate in men with benign prostatic hyperplasia

1993 • 81 citations

Development of Valid Methods to Measure Insulin-Like Growth Factors-I and -II in Bone Cell-Conditioned Medium*

1990 • 79 citations

The induction of new ductal growth in adult prostatic epithelium in response to an embryonic prostatic inductor

1986 • 69 citations

Sex Hormone-Binding Globulin Mediates Prostate Androgen Receptor Action via a Novel Signaling Pathway

1998 • 68 citations

The Role of Insulin‐Like Growth Factors in Prostate Biology

1996 • 60 citations

Benign prostatic hyperplasia and normal prostate aging: differences in types I and II 5 alpha-reductase and steroid hormone receptor messenger ribonucleic acid (mRNA) levels, but not in insulin-like growth factor mRNA levels.

1993 • 59 citations

Immunohistochemical localization of steroid 5 alpha-reductase 2 in the human male fetal reproductive tract and adult prostate.

1996 • 52 citations

Decreased Expression of Wilms’ Tumor Gene WT-1 and Elevated Expression of Insulin Growth Factor-II (IGF-II) and Type 1 IGF Receptor Genes in Prostatic Stromal Cells from Patients with Benign Prostatic Hyperplasia¹

1997 • 50 citations

Secretion of insulin-like growth factors and their binding proteins by human normal and hyperplastic prostatic cells in primary culture.

1996 • 50 citations

Insulin‐Like Growth Factor Receptors

1991 • 48 citations

5 alpha-Androstan-3 alpha,17 beta-diol is a hormone: stimulation of cAMP accumulation in human and dog prostate.

1995 • 47 citations

Insulin-Like Growth Factor-I and -II in Human Benign Prostatic Hyperplasia: Relationship with Binding Proteins 2 and 3 and Androgens

1998 • 41 citations

Insulin-like growth factor-I (IGF-I) and its binding protein IGFBP-4 in human prostatic hyperplastic tissue: gene expression and its cellular localization.

1994 • 40 citations

The Insulin-Like Growth Factor Type I Receptor Stimulates Growth and Suppresses Apoptosis in Prostatic Stromal Cells

1998 • 37 citations

Simultaneous determination of 5α reduced metabolites of testosterone in human plasma

1981 • 32 citations

Androgen Concentrations and Their Receptors in the Periurethral Region Are Higher Than Those of the Subcapsular Zone in Benign Prostatic Hyperplasia (BPH)

1998 • 31 citations

Prostatic involution in men taking finasteride is associated with elevated levels of insulin-like growth factor-binding proteins (IGFBPs)-2, -4, and -5

2000 • 30 citations

Prevalent Decrease of the EGF Content in the Periurethral Zone of BPH Tissue Induced by Treatment With Finasteride or Flutamide

1997 • 24 citations

5 Dihydrotestosterone metabolism

1986 • 23 citations

Insulin‐like growth factor II and androgen receptor expression in the prostate

2000 • 22 citations

Regional distribution of epidermal growth factor, testosterone and dihydrotestosterone in benign prostatic hyperplasia tissue

1995 • 19 citations

VENOUS DRAINAGE AND FUNCTIONAL CONTROL OF THE CANINE PROSTATE GLAND

1977 • 17 citations

Endometrial transcripts of human insulin-like growth factors arise by differential promoter usage

1997 • 16 citations

Sex steroid concentrations in plasma from the canine deferential vein

1983 • 9 citations

The radiographic demonstration of the dynamic transfer of radio-opaque material from the differential vein to the prostate in the dog.

1978 • 6 citations

Deleted Work

1955 • 0 citations