Delayed phytohemagglutinin-stimulated production of adenosine triphosphate by aged human lymphocytes: Possible relation to mitochondrial dysfunction

Adenosine Triphosphate Conservation in Metabolic Regulation

1967 • 878 citations

Assay of picomole amounts of ATP, ADP, and AMP using the luciferase enzyme system

1975 • 408 citations

Impaired Lymphocyte Function in Aged Humans

1974 • 350 citations

Continuous protein synthesis is required to maintain the probability of entry into S phase

1977 • 308 citations

Immune function in aged mice

1977 • 143 citations

Deoxyribonucleoside‐Triphosphate Pools and DNA Synthesis in Synchronized Hamster Cells

1973 • 136 citations

Lipid oxidation by heart mitochondria from young adult and senescent rats

1978 • 117 citations

Cytokinetic analysis of the impaired proliferative response of peripheral lymphocytes from aged humans to phytohemagglutinin.

1979 • 112 citations

Modification of mitochondrial respiration by aging and dietary restriction

1980 • 106 citations

Age-Related Decline in Response to Phytohemagglutinin and Pokeweed Mitogen by Spleen Cells from Hamsters and a Long-Lived Mouse Strain

1973 • 87 citations

Effects of luciferin concentration of the quantitative assay of ATP using crude luciferase preparations

1976 • 85 citations

Oxidative Phosphorylation in Mitochondria from Aged Rats

1959 • 85 citations

Age-dependent Changes in the Oxidative Metabolism in Rat Brain

1977 • 76 citations

Regulation of ATP Pools, rRNA and DNA Synthesis in 3T3 Cells in Response to Serum or Hypoxanthine

1977 • 61 citations

Effect of Aging on the Metabolism of Pyruvate and 3‐Hydroxybutyrate in Nonsynaptic and Synaptic Mitochondria from Rat Brain

1980 • 56 citations

The Increasing Adenine Nucleotide Concentration and the Maturation of Rat Liver Mitochondria during Neonatal Development

1979 • 55 citations

The pool size of deoxyguanosine 5′-triphosphate and deoxycytidine 5′-triphosphate in phytohemagglutinin-stimulated and non-stimulated human lymphocytes

1975 • 52 citations

Quantitation of Mitochondrial Dna and Protein in the Liver of Fischer 344 Rats During Aging

1978 • 47 citations

Rapid changes in initiation-limited rates of protein synthesis in rat thymic lymphocytes correlate with energy charge

1977 • 36 citations

Anti-B Lymphocytotoxins in Renal-Allograft Rejection

1976 • 36 citations

Age-Related Variation in Lymphocyte Subpopulations

1977 • 31 citations

Thymidine kinetics in human lymphocyte transformation: determination of optimal labelling conditions.

1971 • 29 citations

T-cell division and aging

1979 • 19 citations

Effects of withdrawal of a serum stimulus on the protein-synthesizing machinery of cultured fibroblasts

1975 • 16 citations

Effects of age on energy status and redox state of lympocytes during blastogenesis

1981 • 11 citations

Lymphocyte activation

2003 • 3 citations