Cytokinetic analysis of the impaired proliferative response of peripheral lymphocytes from aged humans to phytohemagglutinin.

Do Cells Cycle?

1973 • 885 citations

The relationship between in vitro cellular aging and in vivo human age.

1976 • 559 citations

Impaired Lymphocyte Function in Aged Humans

1974 • 350 citations

Lymphocyte Phytohemagglutinin Responsiveness, Immunoglobulins and Autoantibodies in Aging Humans

1973 • 286 citations

The division cycle and RNA-synthesis in diploid human cells at different passage levels in vitro

1966 • 271 citations

The utilization of bromodeoxyuridine incorporation into DNA for the analysis of cellular kinetics

1976 • 216 citations

Mitogenic Effect of Phytohaemagglutinin at Different Ages

1967 • 204 citations

Impaired Delayed Hypersensitivity in an Aging Population

1968 • 183 citations

Changes in the G0 state of WI-38 fibroblasts at different times after confluence*1

1974 • 173 citations

Immunological studies of Aging. III. Cytokinetic basis for the impaired response of lymphocytes from aged humans to plant lectins.

1977 • 146 citations

Characterization of the cell cycle of cultured human diploid cells: Effects of aging and hydrocortisone

1977 • 137 citations

Cells regulate theri proliferation through alterations in transition probability

1977 • 128 citations

Aging: Noncycling Cells an Explanation

1972 • 114 citations

Decline in Phytohemagglutinin Responsiveness of Spleen Cells from Aging Mice

1973 • 109 citations

The effect of age on regeneration of rat liver.

1950 • 108 citations

Decline in Mixed Lymphocyte Reactivity of Spleen Cells from Aged Mice of a Long-Lived Strain

1973 • 99 citations

Effect of age on cell-mediated immunity in long-lived mice.

1975 • 93 citations

Evidence derived from sister chromatid exchanges of restricted rejoining of chromatid subunits

1975 • 91 citations

Rosette-forming T cells in human peripheral blood at different ages

1974 • 78 citations

AGE-RELATED VARIATION IN PROPORTION OF CIRCULATING T CELLS

1974 • 77 citations

Phytomitogen responses of peripheral blood lymphocytes in young and older subjects.

1974 • 72 citations

The duodenal progenitor population. I. Age related increase in the duration of the cryptal progenitor cycle

1965 • 69 citations

Effect of Age upon Primary Alloantigen Recognition by Mouse Spleen Cells

1971 • 68 citations

Chapter 25 Bromodeoxyuridine Differential Chromatid Staining Technique: A New Approach to Examining Sister Chromatid Exchange and Cell Replication Kinetics

1978 • 67 citations

Age-dependent regulation of mammalian DNA synthesis and cell proliferation In vivo

1972 • 67 citations

Immune function in aged mice

1977 • 66 citations

Change of Cell-Mediated Cytotoxicity with Aging

1975 • 59 citations

Lymphocyte responses to phytohaemagglutinin: age-related effects.

1976 • 56 citations

Functions of the lymphocytes.

1969 • 55 citations

Kidney cell proliferation after unilateral nephrectomy as related to age.

1967 • 51 citations

Effects of prolonged quiescence on nuclei and chromatin of WI‐38 fibroblasts

1976 • 49 citations

In vitro response of lymphocytes to phytohemagglutinin (PHA) as studied with antiserum to PHA

1972 • 48 citations

Age-related changes, including synergy and suppression, in the mixed lymphocyte reaction in long-lived mice

1975 • 44 citations

Age-related refractoriness of PHA-induced lymphocyte transformation. II. 125I-PHA binding to spleen cells from young and old mice

1975 • 43 citations

DECREASED LYMPHOID CELL MULTIPLICATION IN THE POST-THYMECTOMY STATE

1969 • 39 citations

BISACK ANALYSIS OF THE PHYTOHAEMAGGLUTININ‐INDUCED PROLIFERATION OF HUMAN PERIPHERAL LYMPHOCYTES

1979 • 35 citations

Aging and the Generation Cycle of Intestinal Epithelial Cells in the Mouse

1961 • 34 citations

Age and the cell cycle of the mouse esophageal epithelium

1971 • 33 citations

Age-related refractoriness of pha-induced lymphocyte transformation I. Comparable sensitivity of spleen cells from young and old mice to culture conditions

1975 • 32 citations

Age-Related Variation in Lymphocyte Subpopulations

1977 • 31 citations

AGING AND VARIABILITY

1966 • 29 citations

A multiple-parameter comparison of immunocompetence and tumor resistance in aged BALB/c mice

1977 • 28 citations

Kidney cell proliferation after unilateral nephrectomy as related to age

1967 • 22 citations

Cellular Content and Cellular Proliferation Changes in the Tissues and Organs of the Aging Mammal

1971 • 16 citations

Immune Response in Aged and Young Subjects, following Administration of Large Doses of Tuberculin

1975 • 9 citations

Ageing and Cell-Mediated Immunity

1975 • 8 citations

[Blast transformation and mitotic activity of cultivated peripheral blood lymphocytes from persons of different ages].

1974 • 2 citations

[Reactivity of lymphocytes in the aged].

1971 • 2 citations