The mechanisms controlling ribosomal protein L1 pre-mRNA splicing are maintained in evolution and rely on conserved intron sequences

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for site-directed mutagenesis using the polymerase chain reaction

1989 • 607 citations

Regulation by HIV Rev depends upon recognition of splice sites

1989 • 517 citations

Ras C-terminal processing enzymes—New drug targets?

1991 • 461 citations

Albumin Phylogeny for Clawed Frogs (Xenopus)

1977 • 372 citations

Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns.

1990 • 169 citations

The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice.

1989 • 164 citations

Dependence of DNA helix flexibility on base composition

1983 • 158 citations

Control of retroviral RNA splicing through maintenance of suboptimal processing signals.

1990 • 141 citations

Autogenous regulation of splicing of the transcript of a yeast ribosomal protein gene.

1986 • 111 citations

Nucleotide sequence of the L1 ribosomal protein gene of Xenopus laevis: remarkable sequence homology among introns.

1985 • 94 citations

Xenopus laevis ribosomal protein genes: isolation of recombinant cDNA clones and study of the genomic organization

1981 • 91 citations

Expression of two Xenopus laevis ribosomal protein genes in injected frog oocytes

1984 • 83 citations

The segment inversion site of herpes simplex virus type 1 adopts a novel DNA structure.

1987 • 81 citations

The accumulation of mature RNA for the Xenopus laevis ribosomal protein L1 is controlled at the level of splicing and turnover of the precursor RNA.

1987 • 78 citations

Control of Retroviral RNA Splicing through Maintenance of Suboptimal Processing Signals

1990 • 75 citations

The Regulated Production of μ_m and μ_s mRNA Is Dependent on the Relative Efficiencies of μ_s Poly(A) Site Usage and the Cμ4-to-M1 Splice

1989 • 57 citations

Characterization of histone genes isolated fromXenopus laevisandXenopus tropicalisgenomic libraries

1982 • 42 citations

Identification of the sequences responsible for the splicing phenotype of the regulatory intron of the L1 ribosomal protein gene of Xenopus laevis.

1992 • 28 citations

Expression of the gene for ribosomal protein L1 in Xenopus embryos: alteration of gene dosage by microinjection.

1988 • 27 citations

Identification of the Sequences Responsible for the Splicing Phenotype of the Regulatory Intron of the L1 Ribosomal Protein Gene of Xenopus laevis

1992 • 13 citations

Inefficient in vitro splicing of the regulatory intron of the L1 ribosomal protein gene of X.laevis depends on suboptimal splice site sequences

1992 • 11 citations