Simultaneous monitoring of light-induced changes in protein side-group protonation, chromophore isomerization, and backbone motion of bacteriorhodopsin by time-resolved Fourier-transform infrared spectroscopy.

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1990 • 2,969 citations

[69] Isolation of the cell membrane of Halobacterium halobium and its fractionation into red and purple membrane

1974 • 1,690 citations

Functions of a New Photoreceptor Membrane

1973 • 1,078 citations

Bacteriorhodopsin: a light-driven proton pump in Halobacterium Halobium

1975 • 994 citations

Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212

1988 • 497 citations

Role of aspartate-96 in proton translocation by bacteriorhodopsin.

1989 • 348 citations

Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin.

1989 • 318 citations

Light-driven protonation changes of internal aspartic acids of bacteriorhodopsin: an investigation of static and time-resolved infrared difference spectroscopy using [4-13C]aspartic acid labeled purple membrane

1985 • 294 citations

Aspartic acids 96 and 85 play a central role in the function of bacteriorhodopsin as a proton pump.

1989 • 259 citations

Chromophore structure in bacteriorhodopsin's N intermediate: implications for the proton-pumping mechanism

1988 • 242 citations

Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement.

1989 • 203 citations

A defective proton pump, point-mutated bacteriorhodopsin Asp96----Asn is fully reactivated by azide.

1989 • 185 citations

Evidence for light-induced 13-cis , 14-s-cis isomerization in bacteriorhodopsin obtained by FTIR difference spectroscopy using isotopically labelled retinals

1986 • 179 citations

Hydration effects on the photocycle of bacteriorhodopsin in thin layers of purple membrane

1977 • 177 citations

Pathways of the rise and decay of the M photointermediate(s) of bacteriorhodopsin

1990 • 139 citations

On the protein (tyrosine)-chromophore (protonated Schiff base) coupling in bacteriorhodopsin.

1984 • 138 citations

Millisecond Fourier-transform infrared difference spectra of bacteriorhodopsin's M412 photoproduct.

1987 • 123 citations

Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine‐185 protonates and deprotonantes during the photocycle

1988 • 104 citations

Flash spectroscopy of purple membrane

1987 • 86 citations

Independent photocycles of the spectrally distinct forms of bacteriorhodopsin

1988 • 72 citations

Branching reactions in the photocycle of bacteriorhodopsin

1978 • 49 citations

Fourier transform infrared evidence for proline structural changes during the bacteriorhodopsin photocycle.

1989 • 48 citations

KINETIC MODEL OF BACTERIORHODOPSIN PHOTOCYCLE: PATHWAY FROM M STATE TO bR

1989 • 41 citations

VIBRATIONAL SPECTRA OF RHODOPSIN AND BACTERIORHODOPSIN

1989 • 34 citations