Real time monitoring of BMP Smads transcriptional activity during mouse development

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

Manipulating the Mouse Embryo: A Laboratory Manual

2002 • 2,187 citations

NEW EMBO MEMBERS REVIEW: Transcriptional control by the TGF-beta/Smad signaling system

2000 • 1,935 citations

HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

1995 • 1,380 citations

A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.

1995 • 1,118 citations

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.

1995 • 1,021 citations

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

1996 • 959 citations

Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter

2002 • 849 citations

Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

2000 • 823 citations

Genetic Analysis of the Mammalian Transforming Growth Factor-β Superfamily

2002 • 770 citations

Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse

1991 • 646 citations

Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

2001 • 632 citations

Endoglin promotes endothelial cell proliferation and TGF-β/ALK1 signal transduction

2004 • 622 citations

Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A)

1990 • 616 citations

BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

2007 • 514 citations

Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects

1999 • 436 citations

BMP4 is essential for lens induction in the mouse embryo

1998 • 435 citations

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development

1995 • 424 citations

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo

2005 • 417 citations

The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb

2000 • 391 citations

Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation

2001 • 383 citations

Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.

2000 • 364 citations

Involvement of bone morphogenetic protein-4 and bone morphogenetic protein-7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons

1996 • 359 citations

Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development

1999 • 330 citations

Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.

1995 • 326 citations

Bone Morphogenetic Proteins Are Required In Vivo for the Generation of Sympathetic Neurons

1999 • 297 citations

Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3

2002 • 282 citations

Arterial Endothelium-Specific Activin Receptor-Like Kinase 1 Expression Suggests Its Role in Arterialization and Vascular Remodeling

2003 • 273 citations

Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA

2003 • 249 citations

BMP7 Null Mutation in Mice: Developmental Defects in Skeleton, Kidney, and Eye

1997 • 230 citations

Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps

2006 • 229 citations

Bmp6 and Bmp7 Are Required for Cushion Formation and Septation in the Developing Mouse Heart

2001 • 217 citations

Controlling cell fate by bone morphogenetic protein receptors

2003 • 205 citations

BMP signaling is required for septation of the outflow tract of the mammalian heart

2002 • 205 citations

Generation of the primary hair follicle pattern

2006 • 205 citations

Cardiac outflow tract defects in mice lacking ALK2 in neural crest cells

2004 • 184 citations

Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice

2004 • 178 citations

Requirement of Nuclear Factor-κB in Angiotensin II– and Isoproterenol-Induced Cardiac Hypertrophy In Vivo

2005 • 175 citations

Bone Morphogenetic Protein Signaling Is Essential for Terminal Differentiation of the Intestinal Secretory Cell Lineage

2007 • 166 citations

In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis

2004 • 162 citations

Development of Bone Morphogenetic Protein Receptors in the Nervous System and Possible Roles in Regulating trkC Expression

1998 • 162 citations

SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast

2002 • 158 citations

Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo

2006 • 150 citations

Morpho-Regulation of Ectodermal Organs

2004 • 133 citations

BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction

2007 • 124 citations

Expression of ALK-1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development

1997 • 121 citations

BMP‐7 functions as a novel hormone to facilitate liver regeneration

2006 • 120 citations

Expression and misexpression of members of the FGF and TGFβ families of growth factors in the developing mouse pancreas

2003 • 118 citations

Immunohistochemical expression of smads 1-6 in the 15-day gestation mouse embryo: signaling by BMPs and TGF-?s

2001 • 90 citations

Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins

2004 • 88 citations

BMP signaling regulates murine enteric nervous system precursor migration, neurite fasciculation, and patterning via altered Ncam1 polysialic acid addition

2006 • 79 citations

SOX9 specifies the pyloric sphincter epithelium through mesenchymal-epithelial signals

2004 • 74 citations

Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation

2003 • 68 citations

Evaluation of Tet-on system to avoid transgene down-regulation in ex vivo gene transfer to the CNS

2002 • 61 citations

Astrocytoma cell interaction with elastin substrates: Implications for astrocytoma invasive potential

1999 • 42 citations

Sox9 and Nkx2.5 determine the pyloric sphincter epithelium under the control of BMP signaling

2005 • 40 citations

Temporal and spatial regulation of bone morphogenetic protein signaling in late lung development

2007 • 37 citations

Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues

2000 • 35 citations

Bmps: multifunctional regulators of mammalian embryonic development.

1996 • 28 citations