Specific Tryptophan UV-Absorbance Changes Are Probes of the Transition of Rhodopsin to Its Active State

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1990 • 2,969 citations

The probable arrangement of the helices in G protein-coupled receptors.

1993 • 977 citations

From Femtoseconds to Biology: Mechanism of Bacteriorhodopsin's Light-Driven Proton Pump

1991 • 532 citations

THE MOLAR EXTINCTION OF RHODOPSIN

1953 • 444 citations

Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function.

1992 • 439 citations

Structure and Function in Rhodopsin

1995 • 375 citations

Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin.

1992 • 307 citations

A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin.

1994 • 226 citations

Excited-state polarizabilities and dipole moments of diphenylpolyenes and retinal

1983 • 119 citations

Stark effect spectroscopy of tryptophan

1995 • 107 citations

Kinetic interaction between aromatic residues and the retinal chromophore of bacteriorhodopsin during the photocycle

1979 • 103 citations

Near-ultraviolet electronic transitions of the tryptophan chromophore: linear dichroism, fluorescence anisotropy, and magnetic circular dichroism spectra of some indole derivatives

1989 • 94 citations

Resolution of La and Lb bands in methyl indoles by two-photon spectroscopy

1987 • 79 citations

Light-stable rhodopsin. II. An opsin mutant (TRP-265—-Phe) and a retinal analog with a nonisomerizable 11-cis configuration form a photostable chromophore.

1992 • 77 citations

Structural comparison of metarhodopsin II, metarhodopsin III, and opsin based on kinetic analysis of Fourier transform infrared difference spectra

1992 • 49 citations

Photoactivation of rhodopsin involves alterations in cysteine side chains: detection of an S-H band in the Meta I-->Meta II FTIR difference spectrum

1994 • 46 citations

Movement of the retinylidene Schiff base counterion in rhodopsin by one helix turn reverses the pH dependence of the metarhodopsin I to metarhodopsin II transition.

1993 • 43 citations

Environments of the four tryptophans in the extracellular domain of human tissue factor: comparison of results from absorption and fluorescence difference spectra of tryptophan replacement mutants with the crystal structure of the wild-type protein

1995 • 23 citations

Ground and excited state dipole moments of all-t r a n s-retinal and all-t r a n s-retinylidene-n-butylamine in solution

1977 • 15 citations

Fourier transform infrared spectroscopy indicates a major conformational rearrangement in the activation of rhodopsin

1995 • 14 citations