Regulation of cyclin-dependent kinase 5 catalytic activity by phosphorylation

CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors

1997 • 2,201 citations

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1995 • 1,407 citations

Crystal structure of cyclin-dependent kinase 2

1993 • 946 citations

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1994 • 915 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation.

1996 • 592 citations

Structural basis of cyclin-dependent kinase activation by phosphorylation

1996 • 585 citations

A brain-specific activator of cyclin-dependent kinase 5

1994 • 575 citations

A Structural Basis for Substrate Specificities of Protein Ser/Thr Kinases: Primary Sequence Preference of Casein Kinases I and II, NIMA, Phosphorylase Kinase, Calmodulin-Dependent Kinase II, CDK5, and Erk1

1996 • 555 citations

An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator

1995 • 342 citations

Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase.

1994 • 299 citations

Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments.

1993 • 289 citations

Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression.

1992 • 275 citations

Activation of human cyclin-dependent kinases in vitro.

1992 • 242 citations

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization.

1993 • 207 citations

NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1

1995 • 177 citations

Statistical analysis of protein kinase specificity determinants

1998 • 137 citations

Analysis of the expression, distribution and function of cyclin dependent kinase 5 (cdk5) in developing cerebellar macroneurons

1997 • 131 citations

Identification of Functional Domains in the Neuronal Cdk5 Activator Protein

1997 • 115 citations

Regulation of Cyclin D-Dependent Kinase 4 (cdk4) by cdk4-activating kinase

1994 • 96 citations

Interaction of Cyclin-dependent Kinase 5 (Cdk5) and Neuronal Cdk5 Activator in Bovine Brain

1996 • 94 citations

Phosphorylation of human high molecular weight neurofilament protein (hNF-H) by neuronal cyclin-dependent kinase 5 (cdk5)

1997 • 68 citations

CDK‐5‐Mediated Neurofilament Phosphorylation in SHSY5Y Human Neuroblastoma Cells

1999 • 63 citations

Phosphorylation of synthetic fragments of inhibitor‐2 of protein phosphatase‐1 by casein kinase‐1 and ‐2

1994 • 55 citations

P13suc1 associates with a cdc2-like kinase in a multimeric cytoskeletal complex in squid axoplasm

1995 • 34 citations

Bovine neurofilament-enriched preparations contain kinase activity similar to casein kinase I — Neurofilament phosphorylation by casein kinase I (CKI)

1993 • 31 citations