Syncytium Formation in Cultured Human Lymphoid Tissue: Fusion of Implanted HIV Glycoprotein 120/41-Expressing Cells with Native CD4⁺Cells

Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy

1986 • 1,694 citations

The SCID-hu Mouse: Murine Model for the Analysis of Human Hematolymphoid Differentiation and Function

1988 • 1,394 citations

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

1992 • 1,059 citations

Isolation of T-Cell Tropic HTLV-III-Like Retrovirus from Macaques

1985 • 929 citations

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

1986 • 804 citations

Multifactorial Nature of Human Immunodeficiency Virus Disease: Implications for Therapy

1993 • 803 citations

Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization.

1986 • 740 citations

How B and T cells talk to each other

1994 • 659 citations

Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex

1988 • 621 citations

pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

1987 • 620 citations

Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein

1986 • 593 citations

Vacuolar Myelopathy Pathologically Resembling Subacute Combined Degeneration in Patients with the Acquired Immunodeficiency Syndrome

1985 • 548 citations

Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis

1991 • 548 citations

Quantitation of human immunodeficiency virus type 1 infection kinetics

1993 • 516 citations

AIDS Retrovirus Induced Cytopathology: Giant Cell Formation and Involvement of CD4 antigen

1986 • 516 citations

Pathogenesis of Infection with Human Immunodeficiency Virus

1987 • 496 citations

Lymphoid organs function as major reservoirs for human immunodeficiency virus.

1991 • 489 citations

Lipid-anchored influenza hemagglutinin promotes hemifusion, not complete fusion

1994 • 485 citations

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1.

1991 • 432 citations

Oligomeric structure of the human immunodeficiency virus type 1 envelope glycoprotein.

1990 • 360 citations

The cytopathic effect of hiv is associated with apoptosis

1991 • 358 citations

Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles

1992 • 274 citations

Biological and immunological properties of human immunodeficiency virus type 1 envelope glycoprotein: analysis of proteins with truncations and deletions expressed by recombinant vaccinia viruses

1991 • 231 citations

Multinucleate giant cells

1978 • 209 citations

HTLV-III/LAV viral antigens in lymph nodes of homosexual men with persistent generalized lymphadenopathy and AIDS.

1986 • 191 citations

Differential Effects of nef on HIV Replication: Implications for Viral Pathogenesis in the Host

1989 • 183 citations

Infection of human tonsil histocultures: A model for HIV pathogenesis

1995 • 182 citations

In vivo-like growth of human tumors in vitro.

1986 • 177 citations

Removal of cryptic poxvirus transcription termination signals from the human immunodeficiency virus type 1 envelope gene enhances expression and immunogenicity of a recombinant vaccinia virus

1990 • 172 citations

A major mechanism of human immunodeficiency virus-induced cell killing does not involve cell fusion

1987 • 154 citations

Fusion from without directed by human immunodeficiency virus particles

1994 • 153 citations

Restricted movement of lipid and aqueous dyes through pores formed by influenza hemagglutinin during cell fusion.

1994 • 149 citations

Spectrum of Morphologic Changes of Lymph Nodes from Patients with AIDS or AIDS-Related Complexes

1986 • 141 citations

Membrane flux through the pore formed by a fusogenic viral envelope protein during cell fusion.

1993 • 134 citations

Human immunodeficiency virus type 1 in spinal cords of acquired immunodeficiency syndrome patients with myelopathy: expression and replication in macrophages.

1989 • 128 citations

The lymphoid lesions associated with the acquired immunodeficiency syndrome

1983 • 97 citations

A Bioassay for HIV-1 Based on Env-CD4 Interaction

1990 • 83 citations

Pathology of Suspected Acquired Immune Deficiency Syndrome in Children: A Study of Eight Cases

1984 • 81 citations

Early stages of simian immunodeficiency virus infection in lymph nodes. Evidence for high viral load and successive populations of target cells.

1994 • 79 citations

Immunohistochemical, electron microscopic and in situ hybridization evidence for the involvement of lymphatics in the spread of HIV-1

1988 • 70 citations

Perturbation of host-cell membrane is a primary mechanism of HIV cytopathology

1991 • 61 citations

Cell killing by ultraviolet-inactivated human immunodeficiency virus

1986 • 54 citations

Skin toxicity determined in vitro by three-dimensional, native-state histoculture.

1991 • 54 citations

Lymphadenopathy in a Heterogeneous Population at Risk for the Acquired Immunodeficiency Syndrome (AIDS)— A Morphologic Study

1983 • 48 citations

Human immunodeficiency virus-infected multinucleated histiocytes in oropharyngeal lymphoid tissues from two asymptomatic patients.

1991 • 42 citations

Pathogenesis of tumor invasion. II. Aggregate replication.

1960 • 42 citations

Expression of HIV in lymph node cells of LAS patients. Immunohistology, in situ hybridization, and identification of target cells.

1988 • 38 citations

In situ hybridization of human immunodeficiency virus (HTLV‐III) in cryostat sections of lymph nodes of lymphadenopathy syndrome patients

1987 • 35 citations

Animal models for the study of human immunodeficiency virus infections

1992 • 31 citations

The ultrastructural and immunohistochemical demonstration of viral particles in lymph nodes from human immunodeficiency virus-related and non-human immunodeficiency virus-related lymphadenopathy syndromes

1988 • 29 citations

Development and Functional Anatomy of the Human Tonsilla Palatina

1988 • 23 citations

Lymphadenopathy in HIV (HTLV-III/LAV) infected subjects: the role of virus and follicular dendritic cells.

1988 • 18 citations

The Role of T Cell Motility and Cytoskeletal Reorganization in HIV-Induced Syncytium Formation

1994 • 16 citations

Flow cytometric analysis of tumour-draining lymph nodes in breast cancer patients

1992 • 15 citations

Confocal microscopy of cells implanted into tissue blocks: Cell migration in long-term histocultures

1995 • 10 citations

HIV infection and the brain

1991 • 4 citations