The Role of Bestatin-Sensitive Aminopeptidase, Angiotensin Converting Enzyme and Thiorphan-Sensitive "Enkephalinase" in the Potency of Enkephalins in the Guinea-Pig Ileum

Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes.

1976 • 706 citations

The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

1980 • 705 citations

Dynorphin1–8 and dynorphin1–9 are ligands for the κ-subtype of opiate receptor

1982 • 448 citations

Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli.

1983 • 374 citations

Structure-Activity Relationships of Enkephalin-Like Peptides

1980 • 276 citations

SQ 14,225 (D-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme.

1978 • 209 citations

Increase in potencies of opioid peptides after peptidase inhibition

1983 • 143 citations

Evidence that dynorphin-(1–13) acts as an agonist on opioid κ-receptors

1982 • 131 citations

Dipeptidyl-aminopeptidase III of rat brain. Selective affinity for enkephalin and angiotensin.

1982 • 110 citations

1 Carboxypeptidase A

1971 • 74 citations

Inhibition of the enzymatic degradation of leu-enkephalin by puromycin

1978 • 45 citations

The effect of puromycin on the biological activity of Leu‐enkephalin

1979 • 38 citations

Degradation of exogenous enkephalin in the guinea-pig ileum: relative importance of aminopeptidase, enkephalinase and angiotensin converting enzyme activity.

1982 • 36 citations

Enkephalin degradation in the guinea-pig ileum: effect of aminopeptidase inhibitors, puromycin and bestatin.

1983 • 31 citations