Enhanced Effectiveness of Copper Ion Buffering by CUP1 Metallothionein Compared with CRS5 Metallothionein in Saccharomyces cerevisiae

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Methods in Yeast Genetics: A Laboratory Course Manual

1990 • 1,922 citations

METALLOTHIONEIN

1986 • 1,606 citations

Methods in Yeast Genetics — A Laboratory Course Manual

1991 • 1,257 citations

Biochemistry of metallothionein

1988 • 1,222 citations

Determination of sulfhydryl groups with 2,2′- or 4,4′-dithiodipyridine

1967 • 978 citations

[12] High-efficiency transformation of yeast by electroporation

1991 • 798 citations

[69] Overview of metallothionein

1991 • 793 citations

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium.

1994 • 624 citations

MT-III, a brain-specific member of the metallothionein gene family.

1992 • 558 citations

Induction of a New Metallothionein Isoform (MT-IV) Occurs during Differentiation of Stratified Squamous Epithelia

1994 • 556 citations

Metallothioneins: Proteins in search of function

1985 • 445 citations

Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse.

1993 • 381 citations

Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein

1988 • 365 citations

Tandem gene amplification mediates copper resistance in yeast.

1982 • 354 citations

ACE1 regulates expression of the Saccharomyces cerevisiae metallothionein gene.

1988 • 321 citations

Distinct metal-binding configurations in metallothionein.

1985 • 313 citations

Copper metallothionein of yeast, structure of the gene, and regulation of expression.

1984 • 283 citations

Primary structure and transcription of an amplified genetic locus: the CUP1 locus of yeast.

1984 • 279 citations

Yeast metallothionein. Sequence and metal-binding properties.

1985 • 265 citations

Function and Autoregulation of Yeast Copperthionein

1985 • 216 citations

Molecular Biology of Metallothionein Gene Expression

1987 • 214 citations

Metallothionein and other cadmium-binding proteins: recent developments

1990 • 205 citations

CRS5 encodes a metallothionein-like protein in Saccharomyces cerevisiae.

1994 • 173 citations

Yeast metallothionein function in metal ion detoxification.

1986 • 158 citations

Yeast lacking superoxide dismutase. Isolation of genetic suppressors.

1992 • 148 citations

[25] Vectors for expression of cloned genes in yeast: Regulation, overproduction, and underproduction

1991 • 143 citations

The CUP2 gene product regulates the expression of the CUP1 gene, coding for yeast metallothionein.

1989 • 134 citations

Tandemly duplicated upstream control sequences mediate copper-induced transcription of the Saccharomyces cerevisiae copper-metallothionein gene.

1986 • 117 citations

The CUP2 Gene Product, Regulator of Yeast Metallothionein Expression, Is a Copper-Activated DNA-Binding Protein

1989 • 112 citations

A cysteine-rich nuclear protein activates yeast metallothionein gene transcription.

1989 • 98 citations

The CUP2 gene product, regulator of yeast metallothionein expression, is a copper-activated DNA-binding protein.

1989 • 85 citations

Candida glabrata Metallothioneins

1989 • 81 citations

X-ray absorption studies of yeast copper metallothionein.

1988 • 78 citations

Metallothionein in Biology and Medicine

1991 • 72 citations

Memories of metallothionein

1994 • 64 citations

Selective and tandem amplification of a member of the metallothionein gene family in Candida glabrata.

1990 • 59 citations

Roles of metallothionein and related proteins in metal metabolism and toxicity: problems and perspectives.

1986 • 55 citations

Copper- and silver-substituted yeast metallothioneins: Sequential proton NMR assignments reflecting conformational heterogeneity at the C terminus

1993 • 52 citations

Disruption analysis of metallothionein-encoding genes in Candida glabrata

1992 • 30 citations

Luminescence emission from Neurospora copper metallothionein. Time-resolved studies

1989 • 18 citations

Analysis of copper‐induced metallothionein expression using autonomously replicating plasmids in Candida glabrata

1995 • 15 citations