EFFECTS OF SYMPATHETIC INNERVATION AND TEMPERATURE ON THE PROPERTIES OF RAT HEART ADRENOCEPTORS

Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-hydroxydopamine

1968 • 862 citations

"Trophic" influences of nerve on muscle.

1968 • 596 citations

Dibenamine blockade in strips of rabbit aorta and its use in differentiating receptors.

1954 • 165 citations

Myocardial alpha adrenergic receptors and their role in the production of a positive inotropic effect by sympathomimetic agents.

1968 • 146 citations

Chemical sympathectomy of the cat with 6-hydroxydopamine.

1969 • 140 citations

Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by ?-and ?-adrenoceptors

1974 • 135 citations

THYROID HORMONE‐DEPENDENT INTERCONVERSION OF MYOCARDIAL α‐ AND β‐ADRENOCEPTORS IN THE RAT

1977 • 129 citations

Effects of thyroid state on adrenoceptor properties

1974 • 115 citations

Frequency-dependence of the positive inotropic effect of methoxamine and naphazoline mediated by ?-adrenoceptors in the isolated rabbit papillary muscle

1975 • 114 citations

Evidence favouring the Existence of a Single Adrenergic Receptor

1968 • 107 citations

Axonal Delivery of Neuroplasmic Components to Muscle Cells

1967 • 87 citations

Interactions between sympathomimetic amines and blocking agents on the rat ventricle strip.

1966 • 87 citations

Temperature‐induced interconversion of alpha‐and beta‐adrenoceptors in the frog heart.

1976 • 83 citations

Pharmacological characteristics of adrenergic receptors.

1970 • 77 citations

EFFECT OF HYPOTHYROID STATUS ON MYOCARDIAL RESPONSES TO SYMPATHOMIMETIC DRUGS

1971 • 68 citations

Temperature modulation of α‐ and β‐adrenoceptors in the isolated frog heart

1970 • 68 citations

The chemical basis for adrenergic blocking activity in compounds related to dibenamine.

1949 • 62 citations

Inhibition of catecholamine uptake in the isolated rat heart by haloalkylamines related to phenoxybenzamine

1972 • 60 citations

A quantitative study of alpha adrenergic receptors in the spleen and aorta of the rabbit.

1972 • 59 citations

Drugs and the Mechanical Properties of Heart Muscle

1968 • 59 citations

Transformation of Adrenergic Receptors in the Myocardium

1973 • 52 citations

Reactions of dibenamine and some congeners with substances of biological interest in relation to the mechanism of adrenergic blockade.

1954 • 46 citations

Frequency dependence of the α-adrenoceptor-mediated positive inotropic effect in guinea pig heart

1976 • 40 citations

ADRENOTROPIC RECEPTORS IN THE FROG.

1965 • 33 citations

Factors influencing noradrenaline uptake by the perfused spleen of the cat

1968 • 33 citations

Effects of a haloalkylamine on responses to and disposition of sympathomimetic amines

1969 • 30 citations

The chemical transformations of dibenamine and dibenzyline and biological activity.

1953 • 29 citations

Modulator theory of adrenergic receptor mechanism: vessels of the dog hindlimb

1970 • 29 citations

Interchange of adenyl and guanyl cyclases as an explanation for transformation of β- to α-adrenergic responses in the rat atrium

1975 • 28 citations

Adrenergic Receptors

1972 • 27 citations

BLOCKADE OF EPINEPHRINE-INDUCED CARDIOACCELERATION IN THE FROG

1950 • 27 citations

DISSOCIATION OF CARDIAC INOTROPIC AND ADENYLATE CYCLASE ACTIVATING ADRENOCEPTORS

1974 • 22 citations

Temperature‐Dependent Sensitivity of Adrenoreceptors in the Toad's Heart

1973 • 21 citations

The role of metabolism in temperature-dependent supersensitivity of guinea-pig atria to sympathomimetic amines

1972 • 19 citations

Temperature dependence of phenoxybenzamine effects and the adrenoceptor transformation hypothesis

1975 • 18 citations

Lowered Chronotropic Sensitivity of Rat and Frog Hearts to Sympathomimetic Amines Following Cold Acclimation

1974 • 14 citations

Studies on the temperature-dependent sensitivity of mouse atria to adrenergic drugs

1975 • 13 citations

Decrease in effectiveness of phenoxybenzamine after chronic denervation and chronic decentralization of the nictitating membrane of the pithed cat.

1968 • 13 citations

Dissociation of alpha adrenergic receptor protection from inhibition of H-phenoxybenlamine binding in vascular tissue.

1973 • 11 citations

Effect of sympathetic denervation on the alpha receptors of the cat nictitating membrane.

1966 • 11 citations

The effects of temperature on responses of the isolated perfused heart of the guinea pig to catecholamines: A separation of the rate and force responses

1972 • 10 citations

PHYSICAL AND PHARMACOLOGICAL PROPERTIES OF A SERIES OF ULTRA‐LONG‐ACTING LOCAL ANESTHETICS AND NEUROMUSCULAR BLOCKING AGENTS†

1972 • 8 citations

Metabolic inhibition and adrenoceptor interconversion.

1975 • 8 citations

Adrenergic Blocking Agents. V. Synthesis of N - Benzyl - N - (1 - phenoxyisopropyl) - β - chloroethylamine Hydrochloride Labeled with C¹⁴

1952 • 7 citations