Inflammatory bowel disease: the role of environmental factors

Gut flora in health and disease

2003 • 3,233 citations

Inflammatory bowel disease: Etiology and pathogenesis

1998 • 2,095 citations

Mucosal flora in inflammatory bowel disease

2002 • 1,344 citations

Effects of cigarette smoke on the immune system

2002 • 1,164 citations

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats.

1994 • 1,128 citations

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

1995 • 965 citations

The germless theory of allergic disease: revisiting the hygiene hypothesis

2001 • 794 citations

Appendectomy and Protection against Ulcerative Colitis

2001 • 471 citations

Stress and Exacerbation in Ulcerative Colitis: A Prospective Study of Patients Enrolled in Remission

2000 • 426 citations

Pre-illness dietary factors in inflammatory bowel disease.

1997 • 335 citations

Possible role of mycobacteria in inflammatory bowel disease

1984 • 332 citations

Geographic variation of inflammatory bowel disease within the United States

1991 • 292 citations

Rapid development of colitis in NSAID-treated IL-10–deficient mice

2002 • 272 citations

Clustering of increased small intestinal permeability in families with Crohn's disease

1997 • 264 citations

Evidence of persistent measles virus infection in Crohn's disease

1993 • 251 citations

Appendectomy is followed by increased risk of Crohn's disease

2003 • 229 citations

Comparison of enteral nutrition and drug treatment in active Crohn's disease

1991 • 229 citations

IV. Modulation of intestinal inflammation by stress: basic mechanisms and clinical relevance

2001 • 222 citations

Intestinal permeability in patients with Crohn's disease and their first degree relatives.

1992 • 197 citations

Smoking and inflammatory bowel disease

2000 • 164 citations

Role of Appendicitis and Appendectomy in the Pathogenesis of Ulcerative Colitis: A Critical Review

2002 • 163 citations

Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing

2003 • 160 citations

Meta-analysis of the role of oral contraceptive agents in inflammatory bowel disease.

1995 • 147 citations

Mechanisms of initiation and perpetuation of gut inflammation by stress

2002 • 133 citations

Crohn's disease after in-utero measles virus exposure

1996 • 127 citations

Inflammatory Bowel Disease and Smoking—A Review

1998 • 104 citations

CD45RO expression on circulating CD19+ B cells in Crohn's disease correlates with intestinal permeability

1995 • 103 citations

Integrated evolutionary, immunological, and neuroendocrine framework for the pathogenesis of chronic disabling inflammatory diseases

2003 • 88 citations

Controlled trial of antituberculous chemotherapy in Crohn's disease: a five year follow up study

1998 • 84 citations

Gut mucosal response to food antigens in Crohn's disease

2002 • 61 citations

Geographic and Temporal Variations of Sugar and Margarine Consumption in Relation to Crohn’s Disease

1988 • 54 citations

Measles virus serology in Crohn's disease.

1997 • 44 citations

Detection of persistent measles virus infection in Crohn's disease: current status of experimental work

2001 • 41 citations

Prevention is the best defense: probiotic prophylaxis of pouchitis

2003 • 26 citations

Is an Increased Intestinal Permeability a Valid Predictor of Relapse in Crohn Disease?

2001 • 20 citations

Is an Increased Intestinal Permeability a Valid Predictor of Relapse in Crohn Disease?

2001 • 19 citations

On smoking, rats, and inflammatory bowel disease

1999 • 8 citations