Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1998 • 5,063 citations

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

2000 • 3,559 citations

Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1

2004 • 3,278 citations

Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

2003 • 2,691 citations

Oxidative stress in Parkinson's disease

2003 • 2,001 citations

MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE

1989 • 1,717 citations

Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice

2004 • 959 citations

The PINK1/Parkin pathway regulates mitochondrial morphology

2008 • 845 citations

Mitochondrial permeability transition and oxidative stress

2001 • 842 citations

Parkinson's Disease Brain Mitochondrial Complex I Has Oxidatively Damaged Subunits and Is Functionally Impaired and Misassembled

2006 • 703 citations

Origin and functional consequences of the complex I defect in Parkinson's disease

1996 • 629 citations

Inflammation as a causative factor in the aetiology of Parkinson's disease

2007 • 606 citations

PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1

2007 • 584 citations

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

2008 • 524 citations

Mitochondria, Oxidative Damage, and Inflammation in Parkinson's Disease

2003 • 512 citations

Impaired dopamine release and synaptic plasticity in the striatum of PINK1 -deficient mice

2007 • 508 citations

Superoxide sensitivity of the Escherichia coli aconitase.

1991 • 499 citations

DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase

2007 • 467 citations

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1

2007 • 467 citations

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism

2005 • 442 citations

Low platelet mitochondrial complex I and complex II/III activity in early untreated parkinson's disease

1995 • 430 citations

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

2005 • 363 citations

PINK1 protein in normal human brain and Parkinson's disease

2006 • 328 citations

Parkinson's disease: A case‐control study of occupational and environmental risk factors

1990 • 292 citations

Structural and Functional Diversity of the Microbial Kinome

2007 • 268 citations

Electron transfer complexes I and IV of platelets are abnormal in Parkinson's disease but normal in Parkinson-plus syndromes

1993 • 221 citations

Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6

2006 • 204 citations

Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease

1992 • 192 citations

Distribution of PINK1 and LRRK2 in rat and mouse brain

2006 • 182 citations

Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

2007 • 174 citations

C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1

2006 • 141 citations

Mitochondria and Dopamine

2004 • 116 citations

Endometrial Pinopodes and Uterine Receptivity

2003 • 108 citations

Inhibition of brain mitochondrial respiration by dopamine and its metabolites: implications for Parkinson's disease and catecholamine‐associated diseases

2004 • 95 citations

Testing the vicious cycle theory of mitochondrial ROS production: effects of H2O2 and cumene hydroperoxide treatment on heart mitochondria

2006 • 53 citations